A Clinical study of garlicin in treating acute cerebral infarction

Zaixiang Shi; Jiuliang Zhang; Jiansheng Mao; Tiezhong Zhang; Haicong Li; Jinxing Du; Li Huang; Qifu Cao; Bohai Zi; Yiting Shi; Aihua Liu; Qing Wei

doi:10.1007/BF02934149

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A Clinical study of garlicin in treating acute cerebral infarction

Updated：2021-08-27

- A Clinical study of garlicin in treating acute cerebral infarction
- Chinese Journal of Integrative Medicine Vol. 4, Issue 2, Pages: 89-94(1998)
- Affiliations：
  
  1. The China-Japan Friendship Hospital,Beijing
  2. Tenngzhou Central People’s Hospital, Shangdong
  3. The Xuanwu Hospital,Beijing
  4. TCM Hospital of Shunyi County,Beijing
- Author bio：
- Funds：
  
  Supported by the fund from National Natural Science Foundation of China
- DOI：10.1007/BF02934149
  CLC：
- Published：1998，
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Shi, Z., Zhang, J., Mao, J. et al. A Clinical study of garlicin in treating acute cerebral infarction., CJIM 4, 89–94 (1998). https://doi.org/10.1007/BF02934149

Zaixiang Shi, Jiuliang Zhang, Jiansheng Mao, et al. A Clinical study of garlicin in treating acute cerebral infarction. [J]. Chinese Journal of Integrative Medicine 4(2):89-94(1998)
Shi, Z., Zhang, J., Mao, J. et al. A Clinical study of garlicin in treating acute cerebral infarction., CJIM 4, 89–94 (1998). https://doi.org/10.1007/BF02934149 DOI：

Zaixiang Shi, Jiuliang Zhang, Jiansheng Mao, et al. A Clinical study of garlicin in treating acute cerebral infarction. [J]. Chinese Journal of Integrative Medicine 4(2):89-94(1998) DOI： 10.1007/BF02934149.

摘要

Objective: To evaluate the effect of garlicin in treating acute cerebral infarction.Methods: One hundred and one patients of acute cerebral infarction diagnosed by CT were treated with garlicin (garlicin group) and compared with another group of 53 patients treated with ligustrazine (control group). The neurologic deficiency score and neurologic function score were used for evaluation of effect.Results: The effective rates of garlicin and ligustrazine were 89. 36% and 84. 85% respectively. The improvement scores of neurologic function were 18.46±10.69 and 11.94 ± 6.79 respectively. The difference between the two groups was significant. Before treatment the serum level of MDA in the garlicin group was 6.015 ±1.26 nmol/ml

and it decreased to 4. 87 ± 1.16 nmol/ml after treatment

the change being more significant than that of the control group (from 6.02 ±0.73 nmol/ml to 6.47 ±1.04 nmol/ml). The rheological parameters and cerebral blood flow were also improved after garlicin treatment.Conclusion: Garlicin could increase the perfusion flow of brain

improve the microcirculation

and scavenge free radicals so as to relieve the ischemia and reperfusion injury of the brain.

Abstract

and it decreased to 4. 87 ± 1.16 nmol/ml after treatment

improve the microcirculation

and scavenge free radicals so as to relieve the ischemia and reperfusion injury of the brain.

关键词

garlicinacute cerebral infarctionLigustrazinemalonyldialdehydehemorheology

Keywords

garlicinacute cerebral infarctionLigustrazinemalonyldialdehydehemorheology

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Department of Integrative Cardiology, China-Japan Friendship Hospital

Department of Cardiology, China-Japan Friendship Hospital

Department of Endocrinology, the People’s Hospital Affiliated to Fujian Traditional Chinese Medicine University

Department of Tumor and Hematology, Dongzhimen Hospital of Beijing University of Chinese Medicine

. for Research on the Theory of Qi-Blood of Integrated Medicine, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing

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