Treatment of Liver fibrosis of hepatitis B by interferon-α1 and traditional medicine preparationΔ

Cheng Mingliang; Wu Yayun; Huang Kefu; Luo Tianyong; Ding Yisheng; Lu Yinying; Liu Rencai; Wu Jun

doi:10.1007/BF02934181

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Treatment of Liver fibrosis of hepatitis B by interferon-α1 and traditional medicine preparationΔ

Updated：2021-08-27

- Treatment of Liver fibrosis of hepatitis B by interferon-α1 and traditional medicine preparationΔ
- Chinese Journal of Integrative Medicine Vol. 5, Issue 1, Pages: 16-19(1999)
- Affiliations：
  
  Department of Infectious Disease, Affiliated Hospital of Guiyang Medical College,Guiyang
- Author bio：
- Funds：
  
  Δ;Supported by the ”8.5” key project of scientific commission of Guizhou province (1993 No. 2037) and the ”9. 5” brainstormed project of scientific commission of Guizhou province. (1996 No. 1028)
- DOI：10.1007/BF02934181
  CLC：
- Published：1999，
Scan for full text
Mingliang, C., Yayun, W., Kefu, H. et al. Treatment of Liver fibrosis of hepatitis B by interferon-α1 and traditional medicine preparationΔ, ., CJIM 5, 16–19 (1999). https://doi.org/10.1007/BF02934181

Cheng Mingliang, Wu Yayun, Huang Kefu, et al. Treatment of Liver fibrosis of hepatitis B by interferon-α1 and traditional medicine preparationΔ. [J]. Chinese Journal of Integrative Medicine 5(1):16-19(1999)
Mingliang, C., Yayun, W., Kefu, H. et al. Treatment of Liver fibrosis of hepatitis B by interferon-α1 and traditional medicine preparationΔ, ., CJIM 5, 16–19 (1999). https://doi.org/10.1007/BF02934181 DOI：

Cheng Mingliang, Wu Yayun, Huang Kefu, et al. Treatment of Liver fibrosis of hepatitis B by interferon-α1 and traditional medicine preparationΔ. [J]. Chinese Journal of Integrative Medicine 5(1):16-19(1999) DOI： 10.1007/BF02934181.

摘要

Objective: To find the effective method of curing liver fibrosis of hepatitis B.Methods: Using interferon-α1 (IFN-α1) and traditional Chinese medicine (TCM) preparation to treat the patients with liver fibrosis of hepatitis B and observe the changes of indexes including levels of laminin

precollagen type III

hyaluronic acid

liver puncture

ultrasonography and fibergastroscopy before and after treatment.Results: After 3 months treatment

the indexes were lower than those before treatment. There was a significant difference (P < 0.01). Liver biopsy

ultrasonography and fiber-gastroscopy proved that the liver fibrosis was improved. After 6 months the indexes of the hepatofibrosis

blood albumin and globulin levels showed that the differences between the IFN-effective group and the IFN-ineffective group was significant (P < 0.001).Conclusion: Beneficial effect might be obtained by using IFN-cq to suppress the replication of hepatitis B virus and TCM preparation to treat liver fibrosis.

Abstract

precollagen type III

hyaluronic acid

liver puncture

ultrasonography and fibergastroscopy before and after treatment.Results: After 3 months treatment

the indexes were lower than those before treatment. There was a significant difference (P < 0.01). Liver biopsy

ultrasonography and fiber-gastroscopy proved that the liver fibrosis was improved. After 6 months the indexes of the hepatofibrosis

关键词

hepatitis BhepatofibrosisinterferonChinese medical preparationliver biopsylaminin

Keywords

hepatitis BhepatofibrosisinterferonChinese medical preparationliver biopsylaminin

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General Hospital of Tianjin Medical University

Nankai Hospital

The First Hospital Affiliated to Medical College of Zhejiang University

The First Affiliated Hospital, College of Medical Sciences, Zhejiang University

Department of Infectious Diseases, Affiliated Hospital, Guiyang Medical College

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