Clinical and experimental study on treatment of chronic hepatitis B with Yanggan Aoping Mixture

Yu Rongqing; Bi Jianjun; Wang Qianshan; Xue Xuekun; Pan Xuefei; Wu Chundong; Chang Jie; Huang Guojian

doi:10.1007/BF02934183

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Clinical and experimental study on treatment of chronic hepatitis B with Yanggan Aoping Mixture

Updated：2021-08-27

- Clinical and experimental study on treatment of chronic hepatitis B with Yanggan Aoping Mixture
- Chinese Journal of Integrative Medicine Vol. 5, Issue 1, Pages: 20-24(1999)
- Affiliations：
  
  Jiangsu Provincial Hospital of Traditional Chinese Medicine,Nanjing
- Author bio：
- Funds：
- DOI：10.1007/BF02934183
  CLC：
- Published：1999，
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Rongqing, Y., Jianjun, B., Qianshan, W. et al. Clinical and experimental study on treatment of chronic hepatitis B with Yanggan Aoping Mixture., CJIM 5, 20–24 (1999). https://doi.org/10.1007/BF02934183

Yu Rongqing, Bi Jianjun, Wang Qianshan, et al. Clinical and experimental study on treatment of chronic hepatitis B with Yanggan Aoping Mixture. [J]. Chinese Journal of Integrative Medicine 5(1):20-24(1999)
Rongqing, Y., Jianjun, B., Qianshan, W. et al. Clinical and experimental study on treatment of chronic hepatitis B with Yanggan Aoping Mixture., CJIM 5, 20–24 (1999). https://doi.org/10.1007/BF02934183 DOI：

Yu Rongqing, Bi Jianjun, Wang Qianshan, et al. Clinical and experimental study on treatment of chronic hepatitis B with Yanggan Aoping Mixture. [J]. Chinese Journal of Integrative Medicine 5(1):20-24(1999) DOI： 10.1007/BF02934183.

摘要

Objective: To assess the efficacy of Yanggan Aoping Mixture (

YGAPM) in treating hepatitis B.Methods: Patients suffered from chronic hepatitis B were treated with YGAPM. Observe their short- and long-term efficacy and the change of serum hepatitis B virus marker. In experiment

the effects of YGAPM in treating rat’s liver injury as well as HBV-infected tree shrew and duck HBV-infected ducks were observed.Results: In 79 cases of chronic persistent hepatitis

the markedly effective rate was 60.76%

and further raised to 70.00% in follow-up study in 40 cases. In 73 cases of chronic active hepatitis

the markedly effective rate was 60.27%

and further raised to 62.50% in 32 follow-up cases. In the treatment group

85 of the 119 cases (71.43%) with HBeAg-positive were converted to negative. Whereas in the control group

only 40 of 89 HBeAg-positive cases (44. 94%) were converted to negative

P < 0. 01. Results of experimental study showed that negative conversion rate of tree shrew infected with HBV marker was raised

while the duck HBV DNA in infected duck blood was inhibited. Those compared with the control group separately

the difference was markedly significant.Conclusion: YGAPM is an effective drug in treating chronic hepatitis B

and it could effectively convert the marker to negative.

Abstract

Objective: To assess the efficacy of Yanggan Aoping Mixture (

the effects of YGAPM in treating rat’s liver injury as well as HBV-infected tree shrew and duck HBV-infected ducks were observed.Results: In 79 cases of chronic persistent hepatitis

the markedly effective rate was 60.76%

and further raised to 70.00% in follow-up study in 40 cases. In 73 cases of chronic active hepatitis

the markedly effective rate was 60.27%

and further raised to 62.50% in 32 follow-up cases. In the treatment group

85 of the 119 cases (71.43%) with HBeAg-positive were converted to negative. Whereas in the control group

only 40 of 89 HBeAg-positive cases (44. 94%) were converted to negative

P < 0. 01. Results of experimental study showed that negative conversion rate of tree shrew infected with HBV marker was raised

while the duck HBV DNA in infected duck blood was inhibited. Those compared with the control group separately

the difference was markedly significant.Conclusion: YGAPM is an effective drug in treating chronic hepatitis B

and it could effectively convert the marker to negative.

关键词

chronic hepatitis BYanggan Aoping Mixturehepatitis B virus infected tree shrewduck hepatitis B virus infected duck

Keywords

chronic hepatitis BYanggan Aoping Mixturehepatitis B virus infected tree shrewduck hepatitis B virus infected duck

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Related Institution

Carolinas Medical Center

The Seventh People’s Hospital of Hangzhou City

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Department of Hepatopathy, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

Department of Hepatopathy, Zhejiang Hospital of Integrated Traditional and Western Medicine

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