Clinical and Experimental study on treatment of fatty liver of Phlegm-Dampness Stagnation type by Zhiganle capsule

Zhao Wenxia; Duan Rongzhang; Miao Mingsan; Ji Aiying; Jiang Shihong; Chen Tianzhao; Zhang Zhaolan

doi:10.1007/BF02934184

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Clinical and Experimental study on treatment of fatty liver of Phlegm-Dampness Stagnation type by Zhiganle capsule

Updated：2021-08-27

- Clinical and Experimental study on treatment of fatty liver of Phlegm-Dampness Stagnation type by Zhiganle capsule
- Chinese Journal of Integrative Medicine Vol. 5, Issue 1, Pages: 25-28(1999)
- Affiliations：
  
  The First Affiliated Hospital of He’nan College of TCM, He’nan College of Traditional Chinese Medicine,Zhengzhou
- Author bio：
- Funds：
- DOI：10.1007/BF02934184
  CLC：
- Published：1999，
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Wenxia, Z., Rongzhang, D., Mingsan, M. et al. Clinical and Experimental study on treatment of fatty liver of Phlegm-Dampness Stagnation type by Zhiganle capsule., CJIM 5, 25–28 (1999). https://doi.org/10.1007/BF02934184

Zhao Wenxia, Duan Rongzhang, Miao Mingsan, et al. Clinical and Experimental study on treatment of fatty liver of Phlegm-Dampness Stagnation type by Zhiganle capsule. [J]. Chinese Journal of Integrative Medicine 5(1):25-28(1999)
Wenxia, Z., Rongzhang, D., Mingsan, M. et al. Clinical and Experimental study on treatment of fatty liver of Phlegm-Dampness Stagnation type by Zhiganle capsule., CJIM 5, 25–28 (1999). https://doi.org/10.1007/BF02934184 DOI：

Zhao Wenxia, Duan Rongzhang, Miao Mingsan, et al. Clinical and Experimental study on treatment of fatty liver of Phlegm-Dampness Stagnation type by Zhiganle capsule. [J]. Chinese Journal of Integrative Medicine 5(1):25-28(1999) DOI： 10.1007/BF02934184.

摘要

Objective: To explore the mechanism of Zhiganle capsule (

ZGLC) in treating fatty liver of Phlegm-Dampness Stagnation type. Methods: One hundred and forty-six patients were treated with ZGLC

the effects were observed and compared with those treated with Dongbao Gantai(DBGT

) tablets as control. The effect of ZGLC on ethionine induced hyperlipemia model rats was also observed. Results: The effect of ZGLC was obviously better than those of DBGT in relieving or removing symptoms

normalizing the ultrasonic abnormal findings

lowering the serum levels of lipid and enzyme and improving hemorrheologic functions. Experimental study showed that ZGLC could reduce the blood lipids

inhibit the lipid deposition in liver. As compared with the model group

level of triglyceride in the ZGLC treatment group were much lowered (P < 0.01) and the effect was better than those in the control group. Conclusions: ZGLC has the effect of reducing blood triglyceride level

inhibiting lipid deposition in liver and improving hemorrheologic function.

Abstract

Objective: To explore the mechanism of Zhiganle capsule (

ZGLC) in treating fatty liver of Phlegm-Dampness Stagnation type. Methods: One hundred and forty-six patients were treated with ZGLC

the effects were observed and compared with those treated with Dongbao Gantai(DBGT

normalizing the ultrasonic abnormal findings

lowering the serum levels of lipid and enzyme and improving hemorrheologic functions. Experimental study showed that ZGLC could reduce the blood lipids

inhibit the lipid deposition in liver. As compared with the model group

inhibiting lipid deposition in liver and improving hemorrheologic function.

关键词

Zhiganle capsulePhlegm-Dampness Stagnationanimal model of fatty liver

Keywords

Zhiganle capsulePhlegm-Dampness Stagnationanimal model of fatty liver

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