Effect of total saponins of Ginseng leaves on immunity in aged rats

Zhang Kejian; Liu Gengtao

doi:10.1007/BF02934191

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Effect of total saponins of Ginseng leaves on immunity in aged rats

Updated：2021-08-27

- Effect of total saponins of Ginseng leaves on immunity in aged rats
- Chinese Journal of Integrative Medicine Vol. 5, Issue 1, Pages: 50-53(1999)
- Affiliations：
  
  1. Beijing Hospital, National Center for Clinical Laboratories,Beijing
  2. Institute of Materia Medica, Chinese Academy of Medical Sciences,Beijing
- Author bio：
- Funds：
- DOI：10.1007/BF02934191
  CLC：
- Published：1999，
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Kejian, Z., Gengtao, L. Effect of total saponins of Ginseng leaves on immunity in aged rats., CJIM 5, 50–53 (1999). https://doi.org/10.1007/BF02934191

Zhang Kejian, Liu Gengtao. Effect of total saponins of Ginseng leaves on immunity in aged rats. [J]. Chinese Journal of Integrative Medicine 5(1):50-53(1999)
Kejian, Z., Gengtao, L. Effect of total saponins of Ginseng leaves on immunity in aged rats., CJIM 5, 50–53 (1999). https://doi.org/10.1007/BF02934191 DOI：

Zhang Kejian, Liu Gengtao. Effect of total saponins of Ginseng leaves on immunity in aged rats. [J]. Chinese Journal of Integrative Medicine 5(1):50-53(1999) DOI： 10.1007/BF02934191.

摘要

Objective: To explore the effect of total saponins of Ginseng leaves(GS) on the functions of neutrophil and lymphocyte in the aged rats of 20 months.Methods: Three groups of aged rats were injected intraperiton-eally with doses of 12.5 mg/kg

25 kg/mg and 50 mg/kg of GS once daily for 3 days

the declined immunity of spleen lymphocytes (proliferation of spleen lymphocyte

phagocytosis)

superoxide anion and nitric oxide formation were studied and were compared with those of young rats (2 months).Results: The declined immunity of spleen lymphocytes were improved dose-dependently after GS injected.Conclusion: The results indicate that GS may enhance neutrophil and lymphocyte mediated non-specific and specific defense function in aged rats.

Abstract

25 kg/mg and 50 mg/kg of GS once daily for 3 days

the declined immunity of spleen lymphocytes (proliferation of spleen lymphocyte

phagocytosis)

关键词

ginseng saponinsaged ratsneutrophilslymphocytes

Keywords

ginseng saponinsaged ratsneutrophilslymphocytes

references

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Related Institution

Pharmacy College, Jinan University

State Key Laboratory of New-Tech for Chinese Medicine Pharmaceutical Process

Department of Clinical Laboratory, Chinese People’s Liberation Army General Hospital

Deparment of Laboratory Medicine, Wenzhou Medical College

Department of Clinical Laboratory Medicine, Chinese People’s Liberation Army General Hospital and Postgraduate Medical School

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