On glucocorticoid receptors of peripheral leucocytes in patients with Yang-Deficiency

Jia-Qing Zhang; Zhi-Ming Liu; Qing-Ling Huang; Ya Yuan

doi:10.1007/BF02934207

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On glucocorticoid receptors of peripheral leucocytes in patients with Yang-Deficiency

Updated：2021-08-27

- On glucocorticoid receptors of peripheral leucocytes in patients with Yang-Deficiency
- Chinese Journal of Integrative Medicine Vol. 2, Issue 1, Pages: 9-11(1996)
- Affiliations：
  
  Changhai Hospital, Second Military Medical College,Shanghai
- Author bio：
- Funds：
- DOI：10.1007/BF02934207
  CLC：
- Published：1996，
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Zhang, JQ., Liu, ZM., Huang, QL. et al. On glucocorticoid receptors of peripheral leucocytes in patients with Yang-Deficiency., CJIM 2, 9–11 (1996). https://doi.org/10.1007/BF02934207

Jia-Qing Zhang, Zhi-Ming Liu, Qing-Ling Huang, et al. On glucocorticoid receptors of peripheral leucocytes in patients with Yang-Deficiency. [J]. Chinese Journal of Integrative Medicine 2(1):9-11(1996)
Zhang, JQ., Liu, ZM., Huang, QL. et al. On glucocorticoid receptors of peripheral leucocytes in patients with Yang-Deficiency., CJIM 2, 9–11 (1996). https://doi.org/10.1007/BF02934207 DOI：

Jia-Qing Zhang, Zhi-Ming Liu, Qing-Ling Huang, et al. On glucocorticoid receptors of peripheral leucocytes in patients with Yang-Deficiency. [J]. Chinese Journal of Integrative Medicine 2(1):9-11(1996) DOI： 10.1007/BF02934207.

摘要

The leucocytic glucocorticoid receptors (GCR) were estimated in 20 patients with Yang-Deficiency Syndrome using a radioligand binding method and plasma cortisol was measured at the same time. Results showed that the levels of plasma cortisol and leucocytic GCR of patients were all significantly lower than the healthy control group

and the changes were more significant in 10 cases of hypofunction of endocrinopathy with manifestation of Yang-Deficiency and Yang-Deficiency patients aged <40 years. The mechanism and relationship between GCR and plasma cortisol were also discussed in this article.

Abstract

关键词

Yang-Deficiencyglucocorticoid receptorglucocorticoid

Keywords

Yang-Deficiencyglucocorticoid receptorglucocorticoid

references

Sando JJ, et al. ATP-dependent activation of glucocorticoid receptors to the steroid binding form. J Biol Chem 1979; 254: 4772.

Wheer RH, et al. Glucocorticoid receptor activation and inactivation in cultured human lymphocytes. J Biol Chem 1981; 256: 434.

Svec F. Glucocorticoid receptor regulation. Life Sci 1985; 36: 2359

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Department of Integrated Chinese Traditional and Western Medicine, Shaanxi Province Key Traditional Chinese Medicine

Department of Nephrology, Second Affiliated Hospital, Medical School of Xi’an Jiaotong University

Department of Hematology, Second Affiliated Hospital, Medical School of Xi’an Jiaotong University

Medical School of Xi’an Jiaotong University

Changhai Hospital. The Second Military Medical University

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