Clinical study on epidural injected lappaconitine for post-operative analgesia

Min-Guang Chen; Qi-Hao Wang; Yu-Bing Lin; Kong-Li Chen; Hua-Yang Lin; Wei Lin; Qing Lin; Fei Liu

doi:10.1007/BF02934214

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Clinical study on epidural injected lappaconitine for post-operative analgesia

Updated：2021-08-27

- Clinical study on epidural injected lappaconitine for post-operative analgesia
- Chinese Journal of Integrative Medicine Vol. 2, Issue 1, Pages: 26-29(1996)
- Affiliations：
  
  Affiliated People’s Hospital, Fujian College of TCM,Fuzhou
- Author bio：
- Funds：
- DOI：10.1007/BF02934214
  CLC：
- Published：1996，
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Chen, MG., Wang, QH., Lin, YB. et al. Clinical study on epidural injected lappaconitine for post-operative analgesia., CJIM 2, 26–29 (1996). https://doi.org/10.1007/BF02934214

Min-Guang Chen, Qi-Hao Wang, Yu-Bing Lin, et al. Clinical study on epidural injected lappaconitine for post-operative analgesia. [J]. Chinese Journal of Integrative Medicine 2(1):26-29(1996)
Chen, MG., Wang, QH., Lin, YB. et al. Clinical study on epidural injected lappaconitine for post-operative analgesia., CJIM 2, 26–29 (1996). https://doi.org/10.1007/BF02934214 DOI：

Min-Guang Chen, Qi-Hao Wang, Yu-Bing Lin, et al. Clinical study on epidural injected lappaconitine for post-operative analgesia. [J]. Chinese Journal of Integrative Medicine 2(1):26-29(1996) DOI： 10.1007/BF02934214.

摘要

This paper studied the effect and side-effect of epidural injected Lappaconitine (LC) for postoperative analgesia. 50 patients who were operated in the upper abdomen with epidural anesthesia

were randomly divided into 5 groups. The general condition of each group was similar. Group A

C was given LC 4mg

8mg

12mg respectively for observation. Group D

E was given 0.9% NS 6ml and morphine 2mg individually as control. When the operation was finished

LC was injected into the epidural space with single blind method. The result showed the analgesia of LC and its effective time was: group E>C>B>A>D. The analgesic effect of group C was satisfactory. The efficacy and the maintenance time of A

C groups were significantly different from that of group D(P<0.05

P<0.01). Although the effect of group C was less potent than that of group E (morphine injection)

there was no side-effect like that of morphine. It suggested that epidural injected LC for post-operative analgesia is effective and safe.

Abstract

This paper studied the effect and side-effect of epidural injected Lappaconitine (LC) for postoperative analgesia. 50 patients who were operated in the upper abdomen with epidural anesthesia

were randomly divided into 5 groups. The general condition of each group was similar. Group A

C was given LC 4mg

8mg

12mg respectively for observation. Group D

E was given 0.9% NS 6ml and morphine 2mg individually as control. When the operation was finished

C groups were significantly different from that of group D(P<0.05

P<0.01). Although the effect of group C was less potent than that of group E (morphine injection)

there was no side-effect like that of morphine. It suggested that epidural injected LC for post-operative analgesia is effective and safe.

关键词

LappaconitineMorphineepidural spacepost-operative analgesia

Keywords

LappaconitineMorphineepidural spacepost-operative analgesia

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Affiliated People’s Hospital, Fujian College of Traditional Chinese Medicine

Department of Anesthesiology, Hospital Affiliated to Guilin Medical College, Guangxi Zhuang Autonomous Region

Department of Traditional Chinese Medicine, Hospital Affiliated to Guilin Medical College, Guangxi Zhuang Autonomous Region

Department of Urology, Hospital Affiliated to Guilin Medical College, Guangxi Zhuang Autonomous Region

Department of Pharmacology, Chongqing Medical University

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