Clinical observation on diabetic nephropathy treated with alcohol extraction of Flos Abelmoschus manihot

Jiang-Yi Yu; Ning-Ning Xiong; Hui-Fang Guo; Ying Deng

doi:10.1007/BF02934215

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Clinical observation on diabetic nephropathy treated with alcohol extraction of Flos Abelmoschus manihot

Updated：2021-08-27

- Clinical observation on diabetic nephropathy treated with alcohol extraction of Flos Abelmoschus manihot
- Chinese Journal of Integrative Medicine Vol. 2, Issue 1, Pages: 30-32(1996)
- Affiliations：
  
  Department of Renal Disease, The Affiliated Hospital of Nanjing University of TCM,Nanjing
- Author bio：
- Funds：
- DOI：10.1007/BF02934215
  CLC：
- Published：1996，
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Yu, JY., Xiong, NN., Guo, HF. et al. Clinical observation on diabetic nephropathy treated with alcohol extraction of Flos Abelmoschus manihot., CJIM 2, 30–32 (1996). https://doi.org/10.1007/BF02934215

Jiang-Yi Yu, Ning-Ning Xiong, Hui-Fang Guo, et al. Clinical observation on diabetic nephropathy treated with alcohol extraction of Flos Abelmoschus manihot. [J]. Chinese Journal of Integrative Medicine 2(1):30-32(1996)
Yu, JY., Xiong, NN., Guo, HF. et al. Clinical observation on diabetic nephropathy treated with alcohol extraction of Flos Abelmoschus manihot., CJIM 2, 30–32 (1996). https://doi.org/10.1007/BF02934215 DOI：

Jiang-Yi Yu, Ning-Ning Xiong, Hui-Fang Guo, et al. Clinical observation on diabetic nephropathy treated with alcohol extraction of Flos Abelmoschus manihot. [J]. Chinese Journal of Integrative Medicine 2(1):30-32(1996) DOI： 10.1007/BF02934215.

摘要

Sixty-eight cases of Non-Insulin Dependent Diabetes Mellitus complicated with Nephropathy were randomly divided into two groups: the treated group

35 cases treated with alcohol extraction of Flos A-belmoschus manihot

Gliclazide and Captopril Tablets; and the control group

33 cases treated with Gliclazide and Captopril Tablets

over a period of 8 weeks. The total effective rate in the treated and control group were 83.87% and 31.03% respectively (P<0.01)

urinary micro-albumin were 31.7 and 76.3mg/L (P<0.05)

proteinuria were 0.41 and 0.77g/24hr (P<0.01)

blood β-microglobulin were 3317.8 and 3473. 1 hg/ml (P<0.05)

urinary β-microglobulin were 367.2 and 641.5ng/ml (P<0.01)

urinary N-acetyl-β-glucosaminidase (NAG) were 26.3 and 66. 7u/L (P<0.01)

plasma lipid peroxide (LPO) were 6.13 and 8.78 nmol/L (P<0. 05)

and plasma superoxide anion were 8.36 and 10.42 kcpm respectively (P<0.05). It was suggested that alcohol extraction ofAbelmoschus manihot could eliminate oxygen free radicals

alleviate renal tubular-interstitial diseases

improve renal function

and reduce proteinuria.

Abstract

Sixty-eight cases of Non-Insulin Dependent Diabetes Mellitus complicated with Nephropathy were randomly divided into two groups: the treated group

35 cases treated with alcohol extraction of Flos A-belmoschus manihot

Gliclazide and Captopril Tablets; and the control group

33 cases treated with Gliclazide and Captopril Tablets

over a period of 8 weeks. The total effective rate in the treated and control group were 83.87% and 31.03% respectively (P<0.01)

urinary micro-albumin were 31.7 and 76.3mg/L (P<0.05)

proteinuria were 0.41 and 0.77g/24hr (P<0.01)

blood β-microglobulin were 3317.8 and 3473. 1 hg/ml (P<0.05)

urinary β-microglobulin were 367.2 and 641.5ng/ml (P<0.01)

urinary N-acetyl-β-glucosaminidase (NAG) were 26.3 and 66. 7u/L (P<0.01)

plasma lipid peroxide (LPO) were 6.13 and 8.78 nmol/L (P<0. 05)

and plasma superoxide anion were 8.36 and 10.42 kcpm respectively (P<0.05). It was suggested that alcohol extraction ofAbelmoschus manihot could eliminate oxygen free radicals

alleviate renal tubular-interstitial diseases

improve renal function

and reduce proteinuria.

关键词

Flos Abelmoschus manihotnon-insulin dependent diabetes mellitusdiabetic nephropathyurinary N-acetyl-β-glucosaminidaseurinary micro-albuminoxygen free radical

Keywords

Flos Abelmoschus manihotnon-insulin dependent diabetes mellitusdiabetic nephropathyurinary N-acetyl-β-glucosaminidaseurinary micro-albuminoxygen free radical

references

Mogesen CE, Christensen CK. The diabetic kidney from hyperfiltration and microalbumin to end-stage renal failure. Med Clin Nor Ame 1988; 72: 1465.

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