Study on therapeutic mechanism of Xilei powder for peptic ulcer) for peptic ulcer

An-Tian Zhang; Lin-Xue Qian; Jing-Ming Guan; Ya-Ju Du; Zeng-Duo Wang; Shao-Hua Li; Hui-Chun Guo

doi:10.1007/BF02934219

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Study on therapeutic mechanism of Xilei powder for peptic ulcer) for peptic ulcer

Updated：2021-08-27

- Study on therapeutic mechanism of Xilei powder for peptic ulcer) for peptic ulcer
- Chinese Journal of Integrative Medicine Vol. 2, Issue 1, Pages: 39-41(1996)
- Affiliations：
  
  The Second Affiliated Hospital of Harbin Medical University,Harbin
- Author bio：
- Funds：
- DOI：10.1007/BF02934219
  CLC：
- Published：1996，
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Zhang, AT., Qian, LX., Guan, JM. et al. Study on therapeutic mechanism of Xilei powder for peptic ulcer) for peptic ulcer., CJIM 2, 39–41 (1996). https://doi.org/10.1007/BF02934219

An-Tian Zhang, Lin-Xue Qian, Jing-Ming Guan, et al. Study on therapeutic mechanism of Xilei powder for peptic ulcer) for peptic ulcer. [J]. Chinese Journal of Integrative Medicine 2(1):39-41(1996)
Zhang, AT., Qian, LX., Guan, JM. et al. Study on therapeutic mechanism of Xilei powder for peptic ulcer) for peptic ulcer., CJIM 2, 39–41 (1996). https://doi.org/10.1007/BF02934219 DOI：

An-Tian Zhang, Lin-Xue Qian, Jing-Ming Guan, et al. Study on therapeutic mechanism of Xilei powder for peptic ulcer) for peptic ulcer. [J]. Chinese Journal of Integrative Medicine 2(1):39-41(1996) DOI： 10.1007/BF02934219.

摘要

One hundred and twenty-eight patients with active peptic ulcer were treated with Xilei powder for 4 weeks

their PGE2 levels in both serum and gastro-duodenal mucosa were significantly higher than those before treatment (P<0.01). The rate of negative conversion of Helicobacter pylori (HP) showed in 63.3% of cases. The distributed density of HP significantly reduced (P<0.01). These results indicated that Xilei powder could heal ulcer probably owing to the increasing of the PGE2 level in gastro-duodenal mucose

and inhibiting the growth and reproduction of HP so that to eliminate the HP

but did not owing to inhibit the gastric acid secretion and the release of gastrin.

Abstract

One hundred and twenty-eight patients with active peptic ulcer were treated with Xilei powder for 4 weeks

and inhibiting the growth and reproduction of HP so that to eliminate the HP

but did not owing to inhibit the gastric acid secretion and the release of gastrin.

关键词

peptic ulcerXi-Lei powderprostaglandin E2Helicobacter pylori

Keywords

peptic ulcerXi-Lei powderprostaglandin E2Helicobacter pylori

references

Robert A, Schultz JR, Nezamis JE, et al. Gastric antisecretory and antiulcer properties of PGE2 15-mehtyl PGE2 and 16, 16-dimethyl PGE2. Gastroenterology 1976; 70(3): 359.

Vantrappen C. Effect of 15(R)-15-methy prostaglandin E2 (arbaprostil) on the healing of duodenal ulcer. Gastroenterology 1982; 83(2): 357.

Graham DY. Campylobacter pylori and peptic ulcer. Gastroenterology 1989; 96(2): 615.

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Institute of Pharmacology and Toxicology, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic

Department of Pharmacology, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences

Department of Gastroenterology, Peking University First Hospital

Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine

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