Study on abnormality and regulation of T-Lymphocyte subsets in peripheral blood of rheumatoid arthritis patients

Ying-nan Li; Yu-song Zhao; Xiu Li

doi:10.1007/BF02934304

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Study on abnormality and regulation of T-Lymphocyte subsets in peripheral blood of rheumatoid arthritis patients

Updated：2021-08-27

- Study on abnormality and regulation of T-Lymphocyte subsets in peripheral blood of rheumatoid arthritis patients
- Chinese Journal of Integrative Medicine Vol. 8, Issue 3, Pages: 182(2002)
- Affiliations：
  
  Department of Rheumatoid Diseases, the Second Affiliated Hospital to Harbin Medical University,Harbin
- Author bio：
- Funds：
- DOI：10.1007/BF02934304
  CLC：
- Published：2002，
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Li, Yn., Zhao, Ys. & Li, X. Study on abnormality and regulation of T-Lymphocyte subsets in peripheral blood of rheumatoid arthritis patients., CJIM 8, 182 (2002). https://doi.org/10.1007/BF02934304

Ying-nan Li, Yu-song Zhao, Xiu Li. Study on abnormality and regulation of T-Lymphocyte subsets in peripheral blood of rheumatoid arthritis patients. [J]. Chinese Journal of Integrative Medicine 8(3):182(2002)
Li, Yn., Zhao, Ys. & Li, X. Study on abnormality and regulation of T-Lymphocyte subsets in peripheral blood of rheumatoid arthritis patients., CJIM 8, 182 (2002). https://doi.org/10.1007/BF02934304 DOI：

Ying-nan Li, Yu-song Zhao, Xiu Li. Study on abnormality and regulation of T-Lymphocyte subsets in peripheral blood of rheumatoid arthritis patients. [J]. Chinese Journal of Integrative Medicine 8(3):182(2002) DOI： 10.1007/BF02934304.

摘要

To investigate the change of T-lymphocyte subsets in peripheral blood of rheumatoid arthritis (RA) patients and analyze the effects of Fuzheng Qubi Decoction (FZQBD) on T-cell subsets. Thirty RA patients were randomly divided into two groups

and treated with FZQBD or western medicine combination therapy respectively for one month

the percentage of peripheral CD3 +

CD4 +

CD8 + as well as the serum IgG and IgA levels were determined. The percentage of peripheral CD4 +

CD4 + /CD8 + ratio

IgG and IgA levels increased significantly (p < 0.001) in RA patients before treatment. After 1 month of FZQBD treatment

the CD4 + /CD8 + ratio decreased obviously < 0.05). Abnormal cellular immunity exists in RA patients

FZQBD could adjust the abnormal T-lymphocyte subsets to normalize it.

Abstract

and treated with FZQBD or western medicine combination therapy respectively for one month

the percentage of peripheral CD3 +

CD4 +

CD8 + as well as the serum IgG and IgA levels were determined. The percentage of peripheral CD4 +

CD4 + /CD8 + ratio

IgG and IgA levels increased significantly (p < 0.001) in RA patients before treatment. After 1 month of FZQBD treatment

the CD4 + /CD8 + ratio decreased obviously < 0.05). Abnormal cellular immunity exists in RA patients

FZQBD could adjust the abnormal T-lymphocyte subsets to normalize it.

关键词

Rheumatoid Arthritis PatientSimvastatinAmerican GinsengActivate Blood CircuPhlegm Turbidity

Keywords

Rheumatoid Arthritis PatientSimvastatinAmerican GinsengActivate Blood CircuPhlegm Turbidity

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Related Institution

Departmten of Cardiovascular Diseases, Xiyuan Hospital, China Academy of Chinese Medical Science

Department of Cardiology, Guangdong Provincial Hospital of Traditional Chinese Medicine

China Academy of Chinese Medical Sciences, Xiyuan Hospital

Chinese Association of Integrative Medicine

Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology

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