Clinical studies on functional dyspepsia treated with different Dosage-Form of zhishi xiaopi pill recipe

Dan-bo Dou; Gan Cai; Song-po Wang; Ke-zhong Ni; Jing-fen Tang

doi:10.1007/BF02934306

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Clinical studies on functional dyspepsia treated with different Dosage-Form of zhishi xiaopi pill recipe

Updated：2021-08-27

- Clinical studies on functional dyspepsia treated with different Dosage-Form of zhishi xiaopi pill recipe
- Chinese Journal of Integrative Medicine Vol. 8, Issue 3, Pages: 186-190(2002)
- Affiliations：
  
  1. Shuguang Hospital Affiliated to Shanghai TCM University,Shanghai
  2. Shanghai First People’s Hospital,China
  3. Shanghai Tianshan TCM Hospital,China
- Author bio：
- Funds：
- DOI：10.1007/BF02934306
  CLC：
- Published：2002，
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Dou, Db., Cai, G., Wang, Sp. et al. Clinical studies on functional dyspepsia treated with different Dosage-Form of zhishi xiaopi pill recipe., CJIM 8, 186 (2002). https://doi.org/10.1007/BF02934306

Dan-bo Dou, Gan Cai, Song-po Wang, et al. Clinical studies on functional dyspepsia treated with different Dosage-Form of zhishi xiaopi pill recipe. [J]. Chinese Journal of Integrative Medicine 8(3):186-190(2002)
Dou, Db., Cai, G., Wang, Sp. et al. Clinical studies on functional dyspepsia treated with different Dosage-Form of zhishi xiaopi pill recipe., CJIM 8, 186 (2002). https://doi.org/10.1007/BF02934306 DOI：

Dan-bo Dou, Gan Cai, Song-po Wang, et al. Clinical studies on functional dyspepsia treated with different Dosage-Form of zhishi xiaopi pill recipe. [J]. Chinese Journal of Integrative Medicine 8(3):186-190(2002) DOI： 10.1007/BF02934306.

摘要

To explore the clinical effect of three different dosage-forms of Zhishi Xiaopi Pill (ZSXPP

) recipe on functional dyspepsia (FD). The total of 158 patients were included in this study and were randomly divided into four groups. Three group patients of FD were respectively treated with three different dosage-forms of ZSXPP

while the control group were treated with cisapride. The treatment outcome indicated that there was no difference in the total therapeutic efficacies of these four groups. The tension of vagus nerve and the plasma level of motilin in FD patients were significantly increased by the treatment with ZSXPP; the impaired contraction function of lower esophageal sphincter in some FD patients was improved

too. All of three different dosage-forms of ZSXPP were as effective as cisapride on FD. The efficacy was partly due to the improvement of esophageal and gastric dynamics which was probably related to the increasing of the tension of vagus nerve and the plasma level of motilin.

Abstract

To explore the clinical effect of three different dosage-forms of Zhishi Xiaopi Pill (ZSXPP

关键词

functional dyspepsiaTraditional Chinese Medicine Treatmentvagus nervegastrointestinal hormonemotilin

Keywords

functional dyspepsiaTraditional Chinese Medicine Treatmentvagus nervegastrointestinal hormonemotilin

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Department of Gastroenterology, Shengjing Hospital of China Medical University

Department of Gastroenterology, Provincial Hospital of Integrated Traditional and Western Medicine

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Wangjing Hospital, China Academy of Chinese Medical Sciences

The Affiliated Hospital of Nanjing University of Traditional Chinese Medicine

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