Study on preventive effect of jiangu granule on osteoporosis in ovariectomized rats

Yan-ping Lin; Jian-hua Ma; Er-you Feng; Mei-ya Huang

doi:10.1007/BF02934313

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Study on preventive effect of jiangu granule on osteoporosis in ovariectomized rats

Updated：2021-08-27

- Study on preventive effect of jiangu granule on osteoporosis in ovariectomized rats
- Chinese Journal of Integrative Medicine Vol. 8, Issue 3, Pages: 211(2002)
- Affiliations：
  
  Faculty of Orthopedics and Traumatology, Fujian College of TCM,Fuzhou
- Author bio：
- Funds：
- DOI：10.1007/BF02934313
  CLC：
- Published：2002，
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Lin, Yp., Ma, Jh., Feng, Ey. et al. Study on preventive effect of jiangu granule on osteoporosis in ovariectomized rats., CJIM 8, 211 (2002). https://doi.org/10.1007/BF02934313

Yan-ping Lin, Jian-hua Ma, Er-you Feng, et al. Study on preventive effect of jiangu granule on osteoporosis in ovariectomized rats. [J]. Chinese Journal of Integrative Medicine 8(3):211(2002)
Lin, Yp., Ma, Jh., Feng, Ey. et al. Study on preventive effect of jiangu granule on osteoporosis in ovariectomized rats., CJIM 8, 211 (2002). https://doi.org/10.1007/BF02934313 DOI：

Yan-ping Lin, Jian-hua Ma, Er-you Feng, et al. Study on preventive effect of jiangu granule on osteoporosis in ovariectomized rats. [J]. Chinese Journal of Integrative Medicine 8(3):211(2002) DOI： 10.1007/BF02934313.

摘要

To investigate the preventive effect of Jiangu granule (JGG) on experimental primary osteoporosis type I. Osteoporosis model was established through ovary resection of female rats. Bone mineral density (BMD) was measured with double energy X-ray absorptiometry. Level of endocrine markers

including osteocalcin (BGP)

estradiol (E2) and calcitonin (CT) in serum were examined by RIA. And uterus parameters was calculated also. JGG could significantly increase BMD and uterus index

improve the levels of E2 and CT in serum

at the same time reduce the BGP level. JGG can efficiently prevent type I primary osteoporosis or delay its occurrence by enhancing the function of endocrine system

coordinating the action of calcium related hormone

reducing bone turnover rate and increasing BMD.

Abstract

including osteocalcin (BGP)

estradiol (E2) and calcitonin (CT) in serum were examined by RIA. And uterus parameters was calculated also. JGG could significantly increase BMD and uterus index

improve the levels of E2 and CT in serum

at the same time reduce the BGP level. JGG can efficiently prevent type I primary osteoporosis or delay its occurrence by enhancing the function of endocrine system

coordinating the action of calcium related hormone

reducing bone turnover rate and increasing BMD.

关键词

Bone Mineral DensityOsteocalcinuremiaPrimary OsteoporosisSoft Tissue Calcification

Keywords

Bone Mineral DensityOsteocalcinuremiaPrimary OsteoporosisSoft Tissue Calcification

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Beijing University of Chinese Medicine

China Traditional Chinese Medicine Publishing House

Orthopedic Hospital of Guangzhou University of Traditional Chinese Medicine

Fujian University of Chinese Medicine

Wangjing Hospital of China Academy of Chinese Medical Science

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