Study on treatment of 313 patients with mid-late primary hepatocarcinoma by integrated traditional chinese and western medicine

Chang-quan Ling; Zhe Chen; De-zeng Zhu; Chao-qin Yu; Xue-qiang Huang; Xu-ying Wan; Jin Li; Jian Chen; Jian Shen; Guang-shun Yang; Meng-chao Wu

doi:10.1007/BF02934364

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Study on treatment of 313 patients with mid-late primary hepatocarcinoma by integrated traditional chinese and western medicine

Updated：2021-08-27

- Study on treatment of 313 patients with mid-late primary hepatocarcinoma by integrated traditional chinese and western medicine
- Chinese Journal of Integrative Medicine Vol. 7, Issue 4, Pages: 256-260(2001)
- Affiliations：
  
  1. Department of TCM, Changhai Hospital Affiliated to Second Military Medical University,Shanghai
  2. East Surgical Hospital of Liver and Gallbladder Affiliated to Second Military Medical University,China
- Author bio：
- Funds：
- DOI：10.1007/BF02934364
  CLC：
- Published：2001，
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Ling, Cq., Chen, Z., Zhu, Dz. et al. Study on treatment of 313 patients with mid-late primary hepatocarcinoma by integrated traditional chinese and western medicine., CJIM 7, 256–260 (2001). https://doi.org/10.1007/BF02934364

Chang-quan Ling, Zhe Chen, De-zeng Zhu, et al. Study on treatment of 313 patients with mid-late primary hepatocarcinoma by integrated traditional chinese and western medicine. [J]. Chinese Journal of Integrative Medicine 7(4):256-260(2001)
Ling, Cq., Chen, Z., Zhu, Dz. et al. Study on treatment of 313 patients with mid-late primary hepatocarcinoma by integrated traditional chinese and western medicine., CJIM 7, 256–260 (2001). https://doi.org/10.1007/BF02934364 DOI：

Chang-quan Ling, Zhe Chen, De-zeng Zhu, et al. Study on treatment of 313 patients with mid-late primary hepatocarcinoma by integrated traditional chinese and western medicine. [J]. Chinese Journal of Integrative Medicine 7(4):256-260(2001) DOI： 10.1007/BF02934364.

摘要

To evaluate objectively the clinical effect and superiority of integrated traditional Chinese and western medicine (TCM-WM) in treating mid-late hepatocarcinoma. The 313 patients observed were divided randomly into 3 groups

Group I

II and III

they were treated with protocol TACE

protocol PEI and comprehensive conservative therapy respectively. Each group was sub-divided into 2 sub-groups

sub-group A and B

and sub-group As was treated coordinately with different Chinese herbal medicine

Sisheng Decoction to sub-group I A and II A

and cinobufacin or norcantharidin to III A respectively. And Chinese herbal medicine prescribed according to TCM Syndrome Differentiation was also given to all the sub-group As. The integrated therapy showed significant effect in treating mid-late hepatocarcinoma

as it could improve significantly the clinical symptoms and signs

raise the quality of life and prolong the survival time in patients. When TCM-WM cooperated with TACE

it could alleviate the toxic effect and enhance the therapeutic effect of chemotherapy. There was statistical significant difference in clinical effect between the TCM-WM treated groups and the western medicine treated groups (P<0.05). TCM-WM therapy displays not only the action in enhancing the short-term therapeutic effect of treatment in treating mid-late hepatocarcinoma but also shows significant effect in enhancing long-term therapeutic effect and prolonging survival time in patients. It is worth further spreading.

Abstract

Group I

II and III

they were treated with protocol TACE

protocol PEI and comprehensive conservative therapy respectively. Each group was sub-divided into 2 sub-groups

sub-group A and B

and sub-group As was treated coordinately with different Chinese herbal medicine

Sisheng Decoction to sub-group I A and II A

as it could improve significantly the clinical symptoms and signs

raise the quality of life and prolong the survival time in patients. When TCM-WM cooperated with TACE

关键词

mid-late primary hepatocarcinomaintegrated traditional Chinese and Western medicineprospective contrast study

Keywords

mid-late primary hepatocarcinomaintegrated traditional Chinese and Western medicineprospective contrast study

references

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Senn HJ. Clinical Guidance of Tumor. 1st edition. Tianjin: Tianjin Translation Company of Science and Technology, 1992; 132.

Ling CQ. Clinical and experimental studies on the antitoxic and side-effect actions of Sisheng decoction in radiotherapy. J of TCM 1993:12: 733–734.

Ling CQ. Effects of Sisheng decoction on3H-TdR permeate index of lymphocytes in non-synthetic period induced by ultraviolet rays. Chin J Basic TCM 1997; 3(6): 20–22.

Yu RC, Jiang TL, Yu EX. Researches on Tumor. 1st edition. Shanghai: Shanghai Publishing House of Science and Technology, 1991: 243.

Lin PY, Pan JK. Effects of cinobufacini on immunologic function in mice. Chin Patent Med Res 1987; (12) : 20–21

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Related Institution

Center of Hepatopathy, Xiamen Municipal TCM Hospital Affiliated to Fujian TCM College

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