Clinical study on effect of shenlong oral liquid combined with radiotherapy in treating nasopharyngeal carcinoma

Xiao-dong Zhu; An-yu Wang; Shao-feng Wang; Ren-sheng Wang; Long Chen; Lin Li; Hai-jie Lu

doi:10.1007/BF02934367

Your Location：

Home >

Browse articles >

Clinical study on effect of shenlong oral liquid combined with radiotherapy in treating nasopharyngeal carcinoma

Updated：2021-08-27

- Clinical study on effect of shenlong oral liquid combined with radiotherapy in treating nasopharyngeal carcinoma
- Chinese Journal of Integrative Medicine Vol. 7, Issue 4, Pages: 268-272(2001)
- Affiliations：
  
  1. Guangxi Zhuang Autonomous Regional Cancer Hospital, Cancer Hospital Affiliated to Guangxi Medical University,Nanning
  2. The First Affiliated Hospital of Guangxi Medical University,China
- Author bio：
- Funds：
  
  This study was supported by Guangxi Natural Sciences Fund
- DOI：10.1007/BF02934367
  CLC：
- Published：2001，
Scan for full text
Zhu, Xd., Wang, Ay., Wang, Sf. et al. Clinical study on effect of shenlong oral liquid combined with radiotherapy in treating nasopharyngeal carcinoma., CJIM 7, 268–272 (2001). https://doi.org/10.1007/BF02934367

Xiao-dong Zhu, An-yu Wang, Shao-feng Wang, et al. Clinical study on effect of shenlong oral liquid combined with radiotherapy in treating nasopharyngeal carcinoma. [J]. Chinese Journal of Integrative Medicine 7(4):268-272(2001)
Zhu, Xd., Wang, Ay., Wang, Sf. et al. Clinical study on effect of shenlong oral liquid combined with radiotherapy in treating nasopharyngeal carcinoma., CJIM 7, 268–272 (2001). https://doi.org/10.1007/BF02934367 DOI：

Xiao-dong Zhu, An-yu Wang, Shao-feng Wang, et al. Clinical study on effect of shenlong oral liquid combined with radiotherapy in treating nasopharyngeal carcinoma. [J]. Chinese Journal of Integrative Medicine 7(4):268-272(2001) DOI： 10.1007/BF02934367.

摘要

To observe the effect of Shenlong Oral Liquid(SLOL)combined with radiotherapy in treating nasopharyngeal carcinoma (NPC). Effects of the combined therapy

including clinical effects

changes of cellular immunity and side effects

in treating 60 NPC patients (in the treated group) were observed and compared with those of the other 60 patients treated with radiotherapy alone (in the control group). (1)The side effects of radiation in the treated group were lower than those in the control group significantly (P<0.05). (2) The short-term remission rate of nasopharyngeal and neck metastatic tumor in the two groups was not significantly different (P>0.05). (3) The dose for complete remission of nasopharyngeal and neck tumor in the treated group was lower than that in the control group (P<0.01). (4) No change of T-lymphocyte subsets was found in the treated group after treatment

but in the control group

OKT3

OKT4

and OKT4/OKT8 ratio were markedly decreased (P<0.05). (5) The survival rate in the treated group was higher than that in the control group

but with no statistical significance (P=0.0518). The combined therapy of NPC with SLOL and radiotherapy is able to reduce side-effect of radiotherapy

improve the cellular immunity

reduce the dose of radiation for tumor remission and enhance the therapeutic effect of radiotherapy. It showed a trend of raising the long-term survival rate of NPC patients.

Abstract

To observe the effect of Shenlong Oral Liquid(SLOL)combined with radiotherapy in treating nasopharyngeal carcinoma (NPC). Effects of the combined therapy

including clinical effects

changes of cellular immunity and side effects

but in the control group

OKT3

OKT4

and OKT4/OKT8 ratio were markedly decreased (P<0.05). (5) The survival rate in the treated group was higher than that in the control group

but with no statistical significance (P=0.0518). The combined therapy of NPC with SLOL and radiotherapy is able to reduce side-effect of radiotherapy

improve the cellular immunity

reduce the dose of radiation for tumor remission and enhance the therapeutic effect of radiotherapy. It showed a trend of raising the long-term survival rate of NPC patients.

关键词

nasopharyngeal carcinomaradiotherapyChinese Herbal MedicineT-lymphocyte subsets

Keywords

nasopharyngeal carcinomaradiotherapyChinese Herbal MedicineT-lymphocyte subsets

references

Liu TF, Xiu GZ. Summary of National Conference on Nasopharyngeal Carcinoma. Chin J Radiat Oncol 1992; 1 (4): 204–209.

He XY, Huan SL, He SQ. The influence of radiological course of nasopharyngeal cancer on local effects. Chin J Radiat Oncol 1993; 2(4): 221–222.

Chen XZ, Tang QX. The impact of radiotherapy course length on the treatment results of nasopharyngeal carcinoma. Chin J of Cancer 1995; 14 (5): 373–374, 382.

Wang QW, Liu H, Qiao NA, et al. Effects of traditional Chinese medicine on salivary glands in patients with head and neck cancer during radiotherapy. Chin J Integr Med (chin) 1998; 18(11): 662–664.

Wu JL, Pan GY. Clinical observation on effects of Shengshe Decoction on treating adverse reaction induced by radiotherapy in patients with nasopharyngeal carcinoma. New J TCM 1991; 23(2): 40–42.

Huang HW, Zhang P, Xiu BP, et al. Clinical research on the protective function of Shengqi Injection in patients with NPC receiving radiotherapy. Chin J Cancer 1994; 13(6): 520–521, 528.

Chen K, Huang GZ, Jiang Y, et al. Effect of Tianhuang Decoction on immune function of patients with nasopharyngeal carcinoma treated by radiotherapy. The Practical J of Cancer 1995; 10(1): 49–51.

Wu JL, Xiu YQ, Li WX, et al. Phase III study on 411 nasopharyngeal carcinoma patients treated with combined Chinese medicine and radiotherapy. Chin J Radiat Oncol 1999; 8(1):32–34.

Zhang Q, Luo JM. Comparison of effects between radiotherapy plus Chinese materia medica and radiotherapy alone in patients of rhinitis cancer—prospective study of 216 cases. Shanghai J of Traditional Chinese Medicine 1994; (3): 8–11.

Cai WM, Xiu GZ, Hu YH, et al. Long-term results of combination of radiation with Chinese drugs for activating blood circulation to remove stasis in the treatment of nasopharyngeal carcinoma (NPC)—A prospective randomized trial on 188 cases. Chin J Radiat Oncol 1992; 1 (1): 4–6.

FULL TEXT LINK

More>

Views

394

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Study of chinese herbal medicine in treating ascites and its mechanism in regulating lymphatic stomata

Clinical study on treatment of large metastatic cervical lymphnodes of nasopharyngeal carcinoma by Shenlong Liquid in combination with thermotherapy and radiotherapy) in combination with thermotherapy and radiotherapy

Development is a high level inheritance for China Time-honored Brand products

Effect of Chinese herbal medicine for nourishing yin, supplementing qi, and activating blood on the Th1/Th2 immune balance in peripheral blood in patients with primary Sjogren’s syndrome

Potential prevention: Aloe vera mouthwash may reduce radiation-induced oral mucositis in head and neck cancer patients

Related Author

No data

Related Institution

Institute of Cytobiology and Histo-Engineering, Zhejiang University

The First Affiliated Hospital to Guangxi Medical University

Cancer Hospital of Guangxi Medical University

Cardiovascular Diseases Centre, Xiyuan Hospital, China Academy of Chinese Medical Sciences

The First Affiliated Hospital of Medical College of Zhejiang University

Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
Tel：010-62886827, 62877592 Fax：010-62874291
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰