Clinical study on composite salvia miltiorrhizae injection in preventing nitroglycerin controlled hypotension for lowering arterial partial pressure of oxygen induced by hypotension
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Clinical study on composite salvia miltiorrhizae injection in preventing nitroglycerin controlled hypotension for lowering arterial partial pressure of oxygen induced by hypotension
Chinese Journal of Integrative MedicineVol. 8, Issue 1, Pages: 33-35(2002)
Affiliations:
1. Department of Anesthesiology, the First Affiliated Hospital of Hubei Medical University,Wuhan
2. Department of Anesthesiology, Shenzhen Hospital of Peking University, Shenzhen, Guangdon’g Province
Hu, L., Zheng, LM. & Chen, XJ. Clinical study on composite salvia miltiorrhizae injection in preventing nitroglycerin controlled hypotension for lowering arterial partial pressure of oxygen induced by hypotension., CJIM 8, 33–35 (2002). https://doi.org/10.1007/BF02934615
Lan Hu, Li-Min Zheng, Xue-Jun Chen. Clinical study on composite salvia miltiorrhizae injection in preventing nitroglycerin controlled hypotension for lowering arterial partial pressure of oxygen induced by hypotension. [J]. Chinese Journal of Integrative Medicine 8(1):33-35(2002)
Hu, L., Zheng, LM. & Chen, XJ. Clinical study on composite salvia miltiorrhizae injection in preventing nitroglycerin controlled hypotension for lowering arterial partial pressure of oxygen induced by hypotension., CJIM 8, 33–35 (2002). https://doi.org/10.1007/BF02934615DOI:
Lan Hu, Li-Min Zheng, Xue-Jun Chen. Clinical study on composite salvia miltiorrhizae injection in preventing nitroglycerin controlled hypotension for lowering arterial partial pressure of oxygen induced by hypotension. [J]. Chinese Journal of Integrative Medicine 8(1):33-35(2002) DOI: 10.1007/BF02934615.
Clinical study on composite salvia miltiorrhizae injection in preventing nitroglycerin controlled hypotension for lowering arterial partial pressure of oxygen induced by hypotension
摘要
To observe the effects of Salvia miltiorrhizae composita (SMC) on blood gas variations of nitroglycerin (NTG) controlled hypotension. Sixteen patients who were arranged to undergo operation under general anesthesia in controlled hypotension condition were randomly divided into the control group (n=8) and the SMC group ( n= 8). NTG was used to create controlled hypotension in both groups and blood pressure decreased by about 30% compared with the control values. Patients in the SMC group were administered intravenously with SMC (16 ml) before the utilization of NTG. Significant PaO2 decrease and Pa-etCO2 increase were observed in the control group during the controlled hypotension period. However
blood gas values in the SMC group did not obviously change. SMC can prevent the side-effects of NTG on blood gas.
Abstract
To observe the effects of Salvia miltiorrhizae composita (SMC) on blood gas variations of nitroglycerin (NTG) controlled hypotension. Sixteen patients who were arranged to undergo operation under general anesthesia in controlled hypotension condition were randomly divided into the control group (n=8) and the SMC group ( n= 8). NTG was used to create controlled hypotension in both groups and blood pressure decreased by about 30% compared with the control values. Patients in the SMC group were administered intravenously with SMC (16 ml) before the utilization of NTG. Significant PaO2 decrease and Pa-etCO2 increase were observed in the control group during the controlled hypotension period. However
blood gas values in the SMC group did not obviously change. SMC can prevent the side-effects of NTG on blood gas.
关键词
Salvia miltiorrhizae compositaNitroglycerincontrolled hypotensionblood gas
Keywords
Salvia miltiorrhizae compositaNitroglycerincontrolled hypotensionblood gas
references
Mookherjee S, Fuleihan D, Warner RA, et al. Effects of sublingual nitroglycerin on resting pulmonary gas exchange and hemodynamics in man. Circulation 1978; 57: 106–110.
Innami Hiroshi. Effect of nitroglycerin on PaO2. Respir Circ 1992;40(l):29–34.
Hayakawa Jun, Shibata Toshinari, Ono Kenji, et al. Effect on arterial blood oxygen in applying the halothane, NO and oxygen to perform hypotensive anesthesia. Anesthesia 1990; 39(11): 1467–1472.
Tao Zw, Lei Ml, Wang Th, et al. Exploration on effect of high frequency jet-ventilation oxygen supply plus Salvia miltiorrhizae injection intravenous dripping in treating type II respiratory failure. Chin J TB Respir 1989; 12(5): 297–298.
Yu Gr, Zhang Sh, Lu Hh, et al. Effect of Salvia miltiorrhizae on coronary heart diseases patients’ microcirculation, 2,3-DPG and experimental study. Chin J Integr Trad West Med 1988;8(10):596–598.
Ying My, Min Lq. Effect of hypotensive drugs on circulatory function. Foreign Med, Anesthesia and Resuscitation Fascicle 1986;7(6): 329–333.
Lin Jh, Liu Ch, Yao Yq, et al. Observation of Salvia iltiorrhizae in improving nailfold microcirculation and hemorrheologic change of postoperative esophageal and cardiac carcinoma. Chin J Integr Trad West Med 1988; 8(9): 538–540.
Xue Qf, Dai Sl, Wu Yq, et al. Action of ligustrazine and Salvia miltiorrhizae on cheek pouch microcirculation of golden hamster. CMJ 1986;66(6): 334–336.
Xu Jm, Dai Wk, Wang K, et al. Clinical observation of Salvia miltiorrhizae, Clonitrate and large doses of ATP in treating pulmonary encephalopathy. New Med 1984;15(5); 238–239.