Objective: To study the characteristics of plasma norepinephrine (NE) and epinephrine (E) contents alternation and vegetative nervous function disturbance in patients with various Liver Syndrome of TCM.Methods: Subjects were selected on the principle of combination of disease diagnosis and Syndrome Differentiation. Plasma NE and E contents were determined by high performance liquid chromatography (HPLC) and electrochemical detector. The vegetative nervous function were assessed by comprehensive analysis of sympathetic and parasympathetic hyperfunction symptoms

physiologic indexes and physical loading tests.Results: Patients of Liver Excess Syndrome had an elevated plasma NE and E contents and those with the vegetative nervous system disturbance mainly hypersympathetic. On the contrary

patients of Liver Deficiency Syndrome had lowered plasma NE and E contents and those with the vegetative nervous system disturbance mainly hyper-parasympathetic.Conclusion: Plasma NE and E contents and vegetative nervous function disturbance can be taken as the auxiliary laboratory diagnostic indexes for Syndrome Differentiation of Liver Excess and Liver Deficiency.