In this study

48 cases of middle-aged and elderly female diabetes patients were divided randomly into two groups

and treated separately by western medicine alone (glibenclamide)in group A

and by traditional Chinese medicine (herbs that replenish the Kidney and activate blood circulation) and glibenclamide in group B. Before treatment

the patients of both groups had elevated glycosylated hemoglobin (HbAlc) and fast blood glucose (FBG) levels

decreased serum estradiol (E2) and testosterone/estradiol (E2/T) ratio

and the loss of bone mineral (elevated urinary calcium

phosphorus levels). Most of the patients in the two groups had the symptoms of soreness and weakness of the loins and knees

general weakness/dizziness

decreased sexual libido

palpitation and frequent urination

etc. These symptoms in traditional Chinese medicine belong to the deficiency of the Kidney. After treatment in both groups

the patients’ serum HbAlc

FBG

and urinary Beta-2-microglobulin (B2M) got reduced

the concentration of serum sex hormone (E2

E2/T ratio) elevated

and the elimination of urinary calcium

phosphorus levels cut down. But

the therapeutic effect in group B is apparently better than that in group A. The symptoms of deficiency of the Kidney was apparently improved in group B. So

The authors think the medicinal herbs (reinforcing Kidney and activating blood circulation) have an important role in the prevention and treatment of the “Kidney deficiency” and bone mineral loss in middle-aged and elderly female diabetes patients.