Effects of Dachengqi ( ) Decoction on the cytoplasmic free calcium in peritoneal macrophages of mice of bacteria peritonitis) Decoction on the cytoplasmic free calcium in peritoneal macrophages of mice of bacteria peritonitis

Xiu-Zhen Lin; Ping Hu; Jing-Ling Zhang; Xian-zhong Wu

doi:10.1007/BF02934706

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Effects of Dachengqi ( ) Decoction on the cytoplasmic free calcium in peritoneal macrophages of mice of bacteria peritonitis) Decoction on the cytoplasmic free calcium in peritoneal macrophages of mice of bacteria peritonitis

Updated：2021-08-27

- Effects of Dachengqi ( ) Decoction on the cytoplasmic free calcium in peritoneal macrophages of mice of bacteria peritonitis) Decoction on the cytoplasmic free calcium in peritoneal macrophages of mice of bacteria peritonitis
- Chinese Journal of Integrative Medicine Vol. 2, Issue 4, Pages: 296-299(1996)
- Affiliations：
  
  Department of Pharmacology, Tianjin Medical University,Tianjin
- Author bio：
- Funds：
  
  The project is supported by Natural Sciences Foundation of Tianjin
- DOI：10.1007/BF02934706
  CLC：
- Published：1996，
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Lin, XZ., Hu, P., Zhang, JL. et al. Effects of Dachengqi () Decoction on the cytoplasmic free calcium in peritoneal macrophages of mice of bacteria peritonitis) Decoction on the cytoplasmic free calcium in peritoneal macrophages of mice of bacteria peritonitis., CJIM 2, 296–299 (1996). https://doi.org/10.1007/BF02934706

Xiu-Zhen Lin, Ping Hu, Jing-Ling Zhang, et al. Effects of Dachengqi ( ) Decoction on the cytoplasmic free calcium in peritoneal macrophages of mice of bacteria peritonitis) Decoction on the cytoplasmic free calcium in peritoneal macrophages of mice of bacteria peritonitis. [J]. Chinese Journal of Integrative Medicine 2(4):296-299(1996)
Lin, XZ., Hu, P., Zhang, JL. et al. Effects of Dachengqi () Decoction on the cytoplasmic free calcium in peritoneal macrophages of mice of bacteria peritonitis) Decoction on the cytoplasmic free calcium in peritoneal macrophages of mice of bacteria peritonitis., CJIM 2, 296–299 (1996). https://doi.org/10.1007/BF02934706 DOI：

Xiu-Zhen Lin, Ping Hu, Jing-Ling Zhang, et al. Effects of Dachengqi ( ) Decoction on the cytoplasmic free calcium in peritoneal macrophages of mice of bacteria peritonitis) Decoction on the cytoplasmic free calcium in peritoneal macrophages of mice of bacteria peritonitis. [J]. Chinese Journal of Integrative Medicine 2(4):296-299(1996) DOI： 10.1007/BF02934706.

摘要

Effects of Dachengqi Decoction (DCQD) on the cytoplasmic free calcium ([Ca2+ ]) in the peritoneal macrophages (PMϕ) of mice were measured with Ca2+ fluorescent indicator Fura-2/Am. Results showed that the level of Ca2+ in PM<p of the mice with bacterial peritonitis induced by injecting Proteus vulgaris and Escherichia coli in resting was obviously increased compared with that of normal saline (NS) group. In the groups of DCQD

the mice after treated with DCQD for 2 days suffered from bacterial peritonitis

and then they were continuously treated with DCQD for 3 days. Under this condition

the levels of PMϕ[Ca2+ ]i

in resting or when the same doses of CaCI2 were added

were obviously decreased compared with that of the peritonitis model group (P < 0.01). Futhermore

the decrease of Ca2+ levels of DCQD groups was dose dependent. This result shows that DCQD has excellent protective effects on the bacterial peritonitis induced by Proteus vulgaris or Escherichia coli.

Abstract

the mice after treated with DCQD for 2 days suffered from bacterial peritonitis

and then they were continuously treated with DCQD for 3 days. Under this condition

the levels of PMϕ[Ca2+ ]i

in resting or when the same doses of CaCI2 were added

were obviously decreased compared with that of the peritonitis model group (P < 0.01). Futhermore

关键词

Dachengqi decoctionbacteria peritonitisperitoneal macrophagesFura-2/Amfree calcium

Keywords

Dachengqi decoctionbacteria peritonitisperitoneal macrophagesFura-2/Amfree calcium

references

1988:185.

1989;9(8):496.

1995:254.

Grynkiewicz G, Poenie M, Tsien RY. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985;260:3440.

1993;18(3):170.

1990;12(7):37.

Lin XZ, Cui ZQ, Jin ZH and Ma DL. Effects of emodin on the cytoplasmic free calcium in the platelets. J Chin Pharmaceut Sci 1994;3(2):126.

1995;11(2):27.

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Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University

Department of Integrative Medicine, West China Hospital, Sichuan University

Department of General Surgery, First Affiliated Hospital, Dalian Medical University

School of Medicine, Nanjing University Nanjing

Department of Integrated Chinese and Western Medicine, Xiehe Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology

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