Clinical study on treatment of infantile rotaviral enteritis with guava leaf

Lian-bo Wei; Zhi-Jun Li; Bao-Tian Chen; Sheng-Yun Sun; Tu Luan; Yun-Fei Gao; Ji-Lai Li

doi:10.1007/BF02935007

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Clinical study on treatment of infantile rotaviral enteritis with guava leaf

Updated：2021-08-27

- Clinical study on treatment of infantile rotaviral enteritis with guava leaf
- Chinese Journal of Integrative Medicine Vol. 7, Issue 2, Pages: 86-89(2001)
- Affiliations：
  
  Nanfang Hospital of the First Military Medical University,Guangzhou
- Author bio：
- Funds：
- DOI：10.1007/BF02935007
  CLC：
- Published：2001，
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Wei, Lb., Li, ZJ., Chen, BT. et al. Clinical study on treatment of infantile rotaviral enteritis with guava leaf., CJIM 7, 86–89 (2001). https://doi.org/10.1007/BF02935007

Lian-bo Wei, Zhi-Jun Li, Bao-Tian Chen, et al. Clinical study on treatment of infantile rotaviral enteritis with guava leaf. [J]. Chinese Journal of Integrative Medicine 7(2):86-89(2001)
Wei, Lb., Li, ZJ., Chen, BT. et al. Clinical study on treatment of infantile rotaviral enteritis with guava leaf., CJIM 7, 86–89 (2001). https://doi.org/10.1007/BF02935007 DOI：

Lian-bo Wei, Zhi-Jun Li, Bao-Tian Chen, et al. Clinical study on treatment of infantile rotaviral enteritis with guava leaf. [J]. Chinese Journal of Integrative Medicine 7(2):86-89(2001) DOI： 10.1007/BF02935007.

摘要

Objective: To observe the clinical effect of guava leaf (GL) in treating infantile rotaviral enteritis.Methods: Sixty-two patients of rotaviral enteritis were randomly divided into the treated group treated with GL and the control group treated with Gegen Qinlian Decoction. The time for ceasing diarrhea

content of Na+ in blood

content of Na+ and glucose in stool

and the rate of negative conversion of human rotavirus antigen (HRVA) were observed.Results: The 3-day recovery rate in the treated group (87.1 %) was significantly higher than that in the control group (58.1%

P<0.05). The time of ceasing diarrhea in the treated group (25.1 ± 9.5 hrs) was significantly shorter than that in the control group (38. 7 ± 15. 2 hrs

P<0. 01). Moreover

content of Na+ and glucose in stool were reduced obviously in the treated group but not in the control group; and negative conversion rate of HRVA in the former group also got better than that in the latter group (87.1 % vs 58.1%

P<0.05). Consequently

the effect of GL was superior to that of the control significantly.Conclusion: GL has good curative effect on infantile rotaviral enteritis.

Abstract

content of Na+ in blood

content of Na+ and glucose in stool

P<0.05). The time of ceasing diarrhea in the treated group (25.1 ± 9.5 hrs) was significantly shorter than that in the control group (38. 7 ± 15. 2 hrs

P<0. 01). Moreover

P<0.05). Consequently

the effect of GL was superior to that of the control significantly.Conclusion: GL has good curative effect on infantile rotaviral enteritis.

关键词

guava leafchildrenrotavirusenteritis

Keywords

guava leafchildrenrotavirusenteritis

references

Thillainayagam Av, Dias Ja, Salim Afm, et al. Glucose polymer in the fluid therapy of acute diarrhea: studies in a model of rotavirus infection in neonatal rats. Clin Sci 1994; 86:460–477.

Haffejec IE. The epidemiology of rotavirus infections: A global perspective. J Pediatric Gastroenterology and Nutrition 1995;20:275–286.

Wei Lb, Lu Rh, Chen Bt. The effect of guava leaf in antagonizing rotavirus in vitro. World Chinese J Digestion 1999;7(l):895–897.

Ministry of Health of PRC. Guidance on Principle of Clinical Research of Chinese New Drugs. 1st ed. Beijing: 1993, 126-128, 227-229.

Li Jl, Lu Jb, Chen Fl. Thin layer scanning of guaijaverin in guava leaf. J Chinese Materia Medica 1999, 24 (suppl):24–25.

Li Jl, Lu Jb, Chen Fl. Analysis of volatile oil in gauva leaf by GC-MS. J Chinese Materia Medica 1999;22(2): 79–80.

Paul A. Host factor associated with protection against rotavirus disease: The skies are clearing. J of Infectious Dis 1996;174(suppl):59–64.

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Zaozhuang Municipal Hospital of TCM, Shangdong

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