Clinical study on treatment of incipient diabetic nephropathy by integrated traditional Chinese and Western medicine

Fang Bian; Pei-min Zhao; Zhi-sheng Zhang; Yan-ying Li; Feng-xia Wu; Hong-mei Zhang; Qing-mei Zhao; Shu-jun Ji; Shu-he Yan; Jin-xiu Huang

doi:10.1007/BF02935012

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Clinical study on treatment of incipient diabetic nephropathy by integrated traditional Chinese and Western medicine

Updated：2021-08-27

- Clinical study on treatment of incipient diabetic nephropathy by integrated traditional Chinese and Western medicine
- Chinese Journal of Integrative Medicine Vol. 7, Issue 2, Pages: 99-102(2001)
- Affiliations：
  
  Department of Endocrinology, People’s Hospital of Cangzhou,Hebei
- Author bio：
- Funds：
- DOI：10.1007/BF02935012
  CLC：
- Published：2001，
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Bian, F., Zhao, Pm., Zhang, Zs. et al. Clinical study on treatment of incipient diabetic nephropathy by integrated traditional Chinese and Western medicine., CJIM 7, 99–102 (2001). https://doi.org/10.1007/BF02935012

Fang Bian, Pei-min Zhao, Zhi-sheng Zhang, et al. Clinical study on treatment of incipient diabetic nephropathy by integrated traditional Chinese and Western medicine. [J]. Chinese Journal of Integrative Medicine 7(2):99-102(2001)
Bian, F., Zhao, Pm., Zhang, Zs. et al. Clinical study on treatment of incipient diabetic nephropathy by integrated traditional Chinese and Western medicine., CJIM 7, 99–102 (2001). https://doi.org/10.1007/BF02935012 DOI：

Fang Bian, Pei-min Zhao, Zhi-sheng Zhang, et al. Clinical study on treatment of incipient diabetic nephropathy by integrated traditional Chinese and Western medicine. [J]. Chinese Journal of Integrative Medicine 7(2):99-102(2001) DOI： 10.1007/BF02935012.

摘要

Objective: To explore the curative effect of integrated traditional Chinese and western medicinal (TCM-WM) therapy on incipient diabetic nephropathy (DN).Methods: One hundred patients with incipient DN were randomly divided into two groups

the treated group (50 cases) was treated with TCM-WM therapy

which was carried out by using Jiangtang Jianshenling (JTJSL) capsule

a Chinese preparation for supplementing Qi and nourishing Yin

on the basis of effectively controlling blood glucose with western medicine. The 50 patients in the control group were treated with western medicine alone. The course of treatment was three months. Changes of symptoms

signs and related laboratory parameters were observed before and after treatment.Results: The total effective rate in the treated group was 90% while that in the control group 58%

the difference between the two groups was significant (P<0.05). The related parameters including 24 hrs urinary albumin excretion

blood sugar

microalbuminuria

blood and urine (/gb-microglobulin

blood lipids and hemorrheologic parameters were all improved after treatment in the treated group (P <0. 05 orP <0. 01).Conclusion: The curative effect of TCM-WM was better than that of western medicine alone in treating incipient DN.

Abstract

the treated group (50 cases) was treated with TCM-WM therapy

which was carried out by using Jiangtang Jianshenling (JTJSL) capsule

a Chinese preparation for supplementing Qi and nourishing Yin

signs and related laboratory parameters were observed before and after treatment.Results: The total effective rate in the treated group was 90% while that in the control group 58%

the difference between the two groups was significant (P<0.05). The related parameters including 24 hrs urinary albumin excretion

blood sugar

microalbuminuria

blood and urine (/gb-microglobulin

关键词

incipient diabetic nephropathyJiangtang Jianshenling capsuleurinary albumin excretionblood β2-microglobulinurine β2-microglobulinblood lipidhemorrheology

Keywords

incipient diabetic nephropathyJiangtang Jianshenling capsuleurinary albumin excretionblood β2-microglobulinurine β2-microglobulinblood lipidhemorrheology

references

Mogensen CE. Early diabetic renal involvement and nephropathy. In: Alberti Kgmm. Krall Lp (eds). The Diabetes Annual(1/3). Amsterdan: Elsevier, 1987: 306–311.

Wang Xb, Sang Y, Kong Xm, et al. Clinical observation on treatment of non-insulin dependent type of diabetes mellitus accompanied with microalbuminuria by Tangshen capsule combining western medicine. CJIM(Chin) 1997;17(10):622–623.

Lu Rh. Diagnosis and treatment of diabetes mellitus and its complications by traditional Chinese and western medicine. Beijing: People’s Health Publishing House, 1998: 527–531.

Febre J, Balant LP, Dayerpa Lp, et al. The kidney in maturity on set diabetes mellitus: a clinical study on 510 patients. Kidney Int 1982; 21: 730–738.

David M, Neumann L, Lishher M. Plasma lipids and the progression of nephropathy in diabetes mellitus type 2: effect of ACE inhibitors. Kidney Int 1995; 47: 907.

Cao Sf, Fang Fz, An Xy, et al. Significance of microalbuminuria, blood and urine /gb-MG and THP in diagnosis of early stage diabetic nephropathy. Chinese J Nephrology 1992;8(3):164–165.

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