Influence of flavonoid of astragalus membranaceus’s stem and leaf on the function of cell mediated immunity in mice

Yan Jiao; Jie Wen; Xiao-hong Yu; De-shan Zhang

doi:10.1007/BF02935017

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Influence of flavonoid of astragalus membranaceus’s stem and leaf on the function of cell mediated immunity in mice

Updated：2021-08-27

- Influence of flavonoid of astragalus membranaceus’s stem and leaf on the function of cell mediated immunity in mice
- Chinese Journal of Integrative Medicine Vol. 7, Issue 2, Pages: 117-120(2001)
- Affiliations：
  
  Department of Microbiology and Immunology, Heilongjiang University of TCM,Harbin
- Author bio：
- Funds：
- DOI：10.1007/BF02935017
  CLC：
- Published：2001，
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Jiao, Y., Wen, J., Yu, Xh. et al. Influence of flavonoid of astragalus membranaceus’s stem and leaf on the function of cell mediated immunity in mice., CJIM 7, 117–120 (2001). https://doi.org/10.1007/BF02935017

Yan Jiao, Jie Wen, Xiao-hong Yu, et al. Influence of flavonoid of astragalus membranaceus’s stem and leaf on the function of cell mediated immunity in mice. [J]. Chinese Journal of Integrative Medicine 7(2):117-120(2001)
Jiao, Y., Wen, J., Yu, Xh. et al. Influence of flavonoid of astragalus membranaceus’s stem and leaf on the function of cell mediated immunity in mice., CJIM 7, 117–120 (2001). https://doi.org/10.1007/BF02935017 DOI：

Yan Jiao, Jie Wen, Xiao-hong Yu, et al. Influence of flavonoid of astragalus membranaceus’s stem and leaf on the function of cell mediated immunity in mice. [J]. Chinese Journal of Integrative Medicine 7(2):117-120(2001) DOI： 10.1007/BF02935017.

摘要

Objective: To investigate the immune regulation of flavonoid of Astragalus membranaceus’s stem and leaf(FAM-sl).Methods: Changes of total T cell count and subsets in mice were determined by monoantibody assay before and after treatment with FAM-sl

and the lymphokine activated killer cell (LAK) activity was tested simultaneously by isotope label method.Results: FAM-sl could promote the proliferation of lymphocytes induced by ConA

raise the total T cell count and regulate the T cell subsets disturbance

and elevate the LAK activity induced by recombinant interleukin-2 (rIL-2).Conclusion: FAM-sl possesses effects of immune stimulation and immune regulation in treating immunosuppressive mice. This study provides experimental evidence for clinical application of FAM-sl.

Abstract

and the lymphokine activated killer cell (LAK) activity was tested simultaneously by isotope label method.Results: FAM-sl could promote the proliferation of lymphocytes induced by ConA

raise the total T cell count and regulate the T cell subsets disturbance

关键词

flavonoid in Astragalus membranaceus’s stem and leafT lymphocytelymphokine activated killer cellimmune regulation

Keywords

flavonoid in Astragalus membranaceus’s stem and leafT lymphocytelymphokine activated killer cellimmune regulation

references

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