Jiao, Dh., Shen, Xm., Gao, Yp. et al. Clinical study on Rhubarb extract tablet in treating simple obesity., CJIM 7, 33–35 (2001). https://doi.org/10.1007/BF02935106
Dong-hai Jiao, Xue-min Shen, Ya-ping Gao, et al. Clinical study on Rhubarb extract tablet in treating simple obesity. [J]. Chinese Journal of Integrative Medicine 7(1):33-35(2001)
Jiao, Dh., Shen, Xm., Gao, Yp. et al. Clinical study on Rhubarb extract tablet in treating simple obesity., CJIM 7, 33–35 (2001). https://doi.org/10.1007/BF02935106DOI:
Dong-hai Jiao, Xue-min Shen, Ya-ping Gao, et al. Clinical study on Rhubarb extract tablet in treating simple obesity. [J]. Chinese Journal of Integrative Medicine 7(1):33-35(2001) DOI: 10.1007/BF02935106.
Clinical study on Rhubarb extract tablet in treating simple obesity
摘要
Objective: To study the clinical efficacy of Jinghuang tablet (Rhubarb extract tablet
RET) in treating simple obesity.Methods: Four hundred and seventy-two simple obesity patients were randomly divided into 3 pairs of groups: (1) RET-2 treated group (50 cases): treated with RET vs western drug fenfluramine control group (50 cases). (2) RET treated group vs Chinese patent drug Xiaopangmei (XPM) control group with 50 cases randomly divided into each. (3) RET-1 treated group with 137 cases vs blank control of 135 cases. The aim was to observe markedly effective rate
effective rate and side-effect of RET group and fenfluramine and XPM control groups. At the same time
the slimming efficacy of RET-1 treated group and the blank control group were observed.Results: The slimming effective rate of RET is similar to that of fenfluramine (P < 0. 05)
and better than domestically well accepted slimming Chinese patent drug XPM (P < 0.05). In comparing RET-1 group with blank control group
the difference of weight loss of the 2 groups after 1 week treatment was 0.93 kg on average
which was significant.Conclusion: The efficacy of RET in treating simple obesity was similar to that of fenfluramine
but the side-effect was obviously less than that of fenfluramine
while the markedly effective rate and effective rate in slimming were significantly better than that of XPM.
Abstract
Objective: To study the clinical efficacy of Jinghuang tablet (Rhubarb extract tablet
RET) in treating simple obesity.Methods: Four hundred and seventy-two simple obesity patients were randomly divided into 3 pairs of groups: (1) RET-2 treated group (50 cases): treated with RET vs western drug fenfluramine control group (50 cases). (2) RET treated group vs Chinese patent drug Xiaopangmei (XPM) control group with 50 cases randomly divided into each. (3) RET-1 treated group with 137 cases vs blank control of 135 cases. The aim was to observe markedly effective rate
effective rate and side-effect of RET group and fenfluramine and XPM control groups. At the same time
the slimming efficacy of RET-1 treated group and the blank control group were observed.Results: The slimming effective rate of RET is similar to that of fenfluramine (P < 0. 05)
and better than domestically well accepted slimming Chinese patent drug XPM (P < 0.05). In comparing RET-1 group with blank control group
the difference of weight loss of the 2 groups after 1 week treatment was 0.93 kg on average
which was significant.Conclusion: The efficacy of RET in treating simple obesity was similar to that of fenfluramine
but the side-effect was obviously less than that of fenfluramine
while the markedly effective rate and effective rate in slimming were significantly better than that of XPM.
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Related Author
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Related Institution
Department of Pharmaceutical Sciences, Guru Jambheshwar, University of Science and Technology, Hisar
Department of Endocrinology, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology
Department of Traditional Chinese Medicine, Tongji Medical College, Huazhong University of Science and Technology
School of Traditional Chinese Materia Medicine, Shenyang Pharmaceutical University