Clinical study on Shuxuening combined with antipsychotics in treating chronic schizophreniacombined with antipsychotics in treating chronic schizophrenia

He-chun Luo; Yu-cun Shen; Xin Yu; Ping Liu; Chun-xiang Tan; Yu-hua Cui; Fan-qiang Meng; Xu-dong Yang; Jian-cheng Liu; Xue-ying Zhao; Hong-Wen Zhong; Lian-Cheng Zhu; Mei-Lan Zhu

doi:10.1007/BF02935137

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Clinical study on Shuxuening combined with antipsychotics in treating chronic schizophreniacombined with antipsychotics in treating chronic schizophrenia

Updated：2021-08-27

- Clinical study on Shuxuening combined with antipsychotics in treating chronic schizophreniacombined with antipsychotics in treating chronic schizophrenia
- Chinese Journal of Integrative Medicine Vol. 3, Issue 3, Pages: 191-194(1997)
- Affiliations：
  
  1. Mental Health Institute, Beijing Medical University,Beijing
  2. Longquanshan Hospital,Guangxi
  3. Ankang Hospital,Beijing
  4. Minkang Hospital,Beijing
- Author bio：
- Funds：
- DOI：10.1007/BF02935137
  CLC：
- Published：1997，
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Luo, Hc., Shen, Yc., Yu, X. et al. Clinical study on Shuxuening combined with antipsychotics in treating chronic schizophreniacombined with antipsychotics in treating chronic schizophrenia., CJIM 3, 191–194 (1997). https://doi.org/10.1007/BF02935137

He-chun Luo, Yu-cun Shen, Xin Yu, et al. Clinical study on Shuxuening combined with antipsychotics in treating chronic schizophreniacombined with antipsychotics in treating chronic schizophrenia. [J]. Chinese Journal of Integrative Medicine 3(3):191-194(1997)
Luo, Hc., Shen, Yc., Yu, X. et al. Clinical study on Shuxuening combined with antipsychotics in treating chronic schizophreniacombined with antipsychotics in treating chronic schizophrenia., CJIM 3, 191–194 (1997). https://doi.org/10.1007/BF02935137 DOI：

He-chun Luo, Yu-cun Shen, Xin Yu, et al. Clinical study on Shuxuening combined with antipsychotics in treating chronic schizophreniacombined with antipsychotics in treating chronic schizophrenia. [J]. Chinese Journal of Integrative Medicine 3(3):191-194(1997) DOI： 10.1007/BF02935137.

摘要

Objective: To make a preliminary evaluation of the clinical efficacy of Shuxuening (SXN).Methods: One hundred and forty-nine chronic schizophrenic patients were divided randomly into the SXN group and the control group in a double-blind research. SXN was given to the SXN group and placebo to the control group

and patients of both groups went on receiving the previous antipsychotic treatment. Brief Psychiatric Rating Scale (BPRS)

Scale for Assessment of Negative Symptoms (SANS) and Treatment Emergent Symptoms Scale (TESS) were used to assess the effects of treatment and side effects of the drug. The evaluation was done before and during the 2nd

4th

6th

10th and 12 th weeks in the course of treatment.Results: SXN was effective by BPRS evaluation (P < 0.05)

and even the more effective to negative symptoms than positive symptoms by SANS evaluation (P < 0.05). It was safe and with little side effect. In addition

it was found that the incipience of SXN’ s efficacy was somehow related with the course of disease and the daily dosage used.Conclusion: SXN is worthy of further study n the treatment of chronic schizophrenia.

Abstract

and patients of both groups went on receiving the previous antipsychotic treatment. Brief Psychiatric Rating Scale (BPRS)

4th

6th

10th and 12 th weeks in the course of treatment.Results: SXN was effective by BPRS evaluation (P < 0.05)

and even the more effective to negative symptoms than positive symptoms by SANS evaluation (P < 0.05). It was safe and with little side effect. In addition

关键词

chronic schizophreniaflavonesShuxuening

Keywords

chronic schizophreniaflavonesShuxuening

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