Clinical and experimental study on treatment of mid-late stage rheumatoid arthritis with Shuguan Granules ( ))

Zhou Xueping; Zhou Zhongying; Jin Miaowen; Guo Liwei; Fang Taihui; Wang Hong; Xu Huiqin; Wu Mianhua

doi:10.1007/BF02935162

Your Location：

Home >

Browse articles >

Clinical and experimental study on treatment of mid-late stage rheumatoid arthritis with Shuguan Granules ( ))

Updated：2021-08-27

- Clinical and experimental study on treatment of mid-late stage rheumatoid arthritis with Shuguan Granules ( ))
- Chinese Journal of Integrative Medicine Vol. 5, Issue 3, Pages: 165-170(1999)
- Affiliations：
  
  Nanjing University of Traditional Chinese Medicine,Nanjing
- Author bio：
- Funds：
- DOI：10.1007/BF02935162
  CLC：
- Published：1999，
Scan for full text
Xueping, Z., Zhongying, Z., Miaowen, J. et al. Clinical and experimental study on treatment of mid-late stage rheumatoid arthritis with Shuguan Granules ())., CJIM 5, 165–170 (1999). https://doi.org/10.1007/BF02935162

Zhou Xueping, Zhou Zhongying, Jin Miaowen, et al. Clinical and experimental study on treatment of mid-late stage rheumatoid arthritis with Shuguan Granules ( )). [J]. Chinese Journal of Integrative Medicine 5(3):165-170(1999)
Xueping, Z., Zhongying, Z., Miaowen, J. et al. Clinical and experimental study on treatment of mid-late stage rheumatoid arthritis with Shuguan Granules ())., CJIM 5, 165–170 (1999). https://doi.org/10.1007/BF02935162 DOI：

Zhou Xueping, Zhou Zhongying, Jin Miaowen, et al. Clinical and experimental study on treatment of mid-late stage rheumatoid arthritis with Shuguan Granules ( )). [J]. Chinese Journal of Integrative Medicine 5(3):165-170(1999) DOI： 10.1007/BF02935162.

摘要

Objective: To explore the therapeutic mechanism of Shuguan Granule (

SGG) in treating mid-late stage rheumatoid arthritis (RA).Methods: Based on the principle of reinforcing Kidney to treat arthritis

removing phlegm to relieve stasis

two SGG

Shuguan Wenjing (SW) and Shuguan Qingluo (SQ) were prepared and used to treat 44 and 43 mid-late stage patients of RA respectively. The clinical results were compared with those of Wangbi Granule. Animal experiments on the effect of these two SGG were conducted.Results: The total effective rate of the SW

SQ and control group was 88.64%

93.02% and 73.17% respectively. Results of experimental studies in rats with adjuvant-induced arthritis showed that the two SGG obviously raise the level of serum superoxide dismutase

and lowered the levels of serum interleukin-1

plasma prostaglandin E2 and thromboxane B2

as compared with the model group

the difference was significant (P < 0.05

P < 0.01).Conclusion: The two SGG have a comprehensive function of anti-inflammatory

analgesic

antioxidatory

antihypercoagulatory and immunoregulatory effect.

Abstract

Objective: To explore the therapeutic mechanism of Shuguan Granule (

SGG) in treating mid-late stage rheumatoid arthritis (RA).Methods: Based on the principle of reinforcing Kidney to treat arthritis

removing phlegm to relieve stasis

two SGG

SQ and control group was 88.64%

93.02% and 73.17% respectively. Results of experimental studies in rats with adjuvant-induced arthritis showed that the two SGG obviously raise the level of serum superoxide dismutase

and lowered the levels of serum interleukin-1

plasma prostaglandin E2 and thromboxane B2

as compared with the model group

the difference was significant (P < 0.05

P < 0.01).Conclusion: The two SGG have a comprehensive function of anti-inflammatory

analgesic

antioxidatory

antihypercoagulatory and immunoregulatory effect.

关键词

rheumatoid arthritisShuguan Wenjing granuleShuguan Qingluo granuleanti-inflammationimmune function

Keywords

rheumatoid arthritisShuguan Wenjing granuleShuguan Qingluo granuleanti-inflammationimmune function

references

1996: 456.

1993: 210–214.

1993: 110–121.

1987; 7(2): 42–43.

1991: 1241–1243.

1997; 14(2): 100.

1992; 21(3): 180–182.

1992; 7(3): 137–139.

1986; 6(2): 121–124.

FULL TEXT LINK

More>

Views

324

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

How does Chinese medicine target cytokine imbalance in rheumatoid arthritis?

Logistic regression analysis of damp-heat and cold-damp impeding syndrome of rheumatoid arthritis: A perspective in Chinese medicine

A one-year evaluation of radiographic progression in patients with rheumatoid arthritis treated by Qingre Huoxue Decoction (清热活血方)

Fuzheng Yiliu Granule (扶正抑瘤颗粒) inhibits the growth of hepatocellular cancer by regulating immune function and inducing apoptosis in vivo and in vitro

Effect of electro-acupuncture on tumor necrosis factor-α and vascular endothelial growth factor in peripheral blood and joint synovia of patients with rheumatoid arthritis

Related Author

No data

Related Institution

Anhui University of Chinese Medicine

Department of Rheumatism Immunity, First Affiliated Hospital, Anhui University of Chinese Medicine

Department of Health Statistics, Third Military Medical University

Department of Rheumatology, Southwest Hospital, Third Military Medical University

School of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine

Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
Tel：010-62886827, 62877592 Fax：010-62874291
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰