Jialing, Z., Qi, Z., Xiaoling, Y. et al. Clinical observation on side effects of various Tripterygium wilfordii preparations., CJIM 5, 171–175 (1999). https://doi.org/10.1007/BF02935164
Zhou Jialing, Zhu Qi, Yang Xiaoling, et al. Clinical observation on side effects of various Tripterygium wilfordii preparations. [J]. Chinese Journal of Integrative Medicine 5(3):171-175(1999)
Jialing, Z., Qi, Z., Xiaoling, Y. et al. Clinical observation on side effects of various Tripterygium wilfordii preparations., CJIM 5, 171–175 (1999). https://doi.org/10.1007/BF02935164DOI:
Zhou Jialing, Zhu Qi, Yang Xiaoling, et al. Clinical observation on side effects of various Tripterygium wilfordii preparations. [J]. Chinese Journal of Integrative Medicine 5(3):171-175(1999) DOI: 10.1007/BF02935164.
Clinical observation on side effects of various Tripterygium wilfordii preparations
摘要
Objective: To observe the side effects of various Tripterygium wilfordii (TW) preparations in treating rheumatoid arthritis (RA).Methods: The total of 271 patients with RA were treated with various TW preparations to observe the occurrence of side effects.Results: The influence on reproductive system with TW preparations extracted from the TW leaves (Leino ester tablet
LE) was milder than that extracted from the roots (TW tablets and TW polyglycoside tablets
TWP). In the TWP group
the rate of side effect of 60 mg daily was higher than that of 30 mg daily
P < 0.01. The main effects on digestive system and irregular menstruation occurred before 50 years in age
while it was kidney impairment after the age of 50. Those side effects occurred within the first ten years in long-term application. The side effects of TWP produced in the Damp-Heat Stagnation type of RA was much lower than Liver and Kidney Yin Deficiency type of RA
P < 0.05.Conclusion: TW Leino ester tablet is indicated for young woman
and small dosage of TWP tablet is indicated for maintenance therapy
particularly to the Damp-Heat type of RA.
Abstract
Objective: To observe the side effects of various Tripterygium wilfordii (TW) preparations in treating rheumatoid arthritis (RA).Methods: The total of 271 patients with RA were treated with various TW preparations to observe the occurrence of side effects.Results: The influence on reproductive system with TW preparations extracted from the TW leaves (Leino ester tablet
LE) was milder than that extracted from the roots (TW tablets and TW polyglycoside tablets
TWP). In the TWP group
the rate of side effect of 60 mg daily was higher than that of 30 mg daily
P < 0.01. The main effects on digestive system and irregular menstruation occurred before 50 years in age
while it was kidney impairment after the age of 50. Those side effects occurred within the first ten years in long-term application. The side effects of TWP produced in the Damp-Heat Stagnation type of RA was much lower than Liver and Kidney Yin Deficiency type of RA
P < 0.05.Conclusion: TW Leino ester tablet is indicated for young woman
and small dosage of TWP tablet is indicated for maintenance therapy
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Related Author
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Related Institution
Anhui University of Chinese Medicine
Department of Rheumatism Immunity, First Affiliated Hospital, Anhui University of Chinese Medicine
Department of Health Statistics, Third Military Medical University
Department of Rheumatology, Southwest Hospital, Third Military Medical University