Effects of 24 Chinese medicinal herbs on nucleic acid, protein and cell cycle of human lung adenocarcinoma cells

Ming-Quan Han; Jia-Xiang Liu; Hong Gao; Yan-Wei Zhu; Shan-Xiang Chen

doi:10.1007/BF02935358

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Effects of 24 Chinese medicinal herbs on nucleic acid, protein and cell cycle of human lung adenocarcinoma cells

Updated：2021-08-27

- Effects of 24 Chinese medicinal herbs on nucleic acid, protein and cell cycle of human lung adenocarcinoma cells
- Chinese Journal of Integrative Medicine Vol. 3, Issue 2, Pages: 105-108(1997)
- Affiliations：
  
  Longhua Hospital, Shanghai University of Traditional Chinese Medicine and Pharmacology,Shanghai
- Author bio：
- Funds：
- DOI：10.1007/BF02935358
  CLC：
- Published：1997，
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Han, MQ., Liu, JX., Gao, H. et al. Effects of 24 Chinese medicinal herbs on nucleic acid, protein and cell cycle of human lung adenocarcinoma cells., CJIM 3, 105–108 (1997). https://doi.org/10.1007/BF02935358

Ming-Quan Han, Jia-Xiang Liu, Hong Gao, et al. Effects of 24 Chinese medicinal herbs on nucleic acid, protein and cell cycle of human lung adenocarcinoma cells. [J]. Chinese Journal of Integrative Medicine 3(2):105-108(1997)
Han, MQ., Liu, JX., Gao, H. et al. Effects of 24 Chinese medicinal herbs on nucleic acid, protein and cell cycle of human lung adenocarcinoma cells., CJIM 3, 105–108 (1997). https://doi.org/10.1007/BF02935358 DOI：

Ming-Quan Han, Jia-Xiang Liu, Hong Gao, et al. Effects of 24 Chinese medicinal herbs on nucleic acid, protein and cell cycle of human lung adenocarcinoma cells. [J]. Chinese Journal of Integrative Medicine 3(2):105-108(1997) DOI： 10.1007/BF02935358.

摘要

Objective: To study the effects of 24 Chinese medicinal herbs on nucleic acid

protein and cell cycle of human lung adenocarcinoma cells.Methods: Using flow cytometry the authors analysed the effects of 24 Chinese medicinal herbs (CMH) in compound recipe on proliferation index (PI)

DNA index

protein index and ratio of various phases in cell cycle of human lung adenocarcinoma cells (SPC-A-1).Results: The PI was more than 20%

in 4 CMH

while 3 CMH

Gynostemma Pentaphylla

Radix Glehnia

and Radix Ginseng could strengthen the body resistance. That suggested using CMH of strengthening body resistance could not only serve as conventional tonic but also as tumor cell inhibitor. Meanwhile the action points of 24 CMH on cell cycle were different from one another.Conclusions: According to these results

Chinese recipes were more effective in clinical practice.

Abstract

Objective: To study the effects of 24 Chinese medicinal herbs on nucleic acid

DNA index

protein index and ratio of various phases in cell cycle of human lung adenocarcinoma cells (SPC-A-1).Results: The PI was more than 20%

in 4 CMH

while 3 CMH

Gynostemma Pentaphylla

Radix Glehnia

Chinese recipes were more effective in clinical practice.

关键词

Chinese medicinal herbs of strengthening body resistanceFlow Cytometrylung cancercell cyclenucleic acidprotein

Keywords

Chinese medicinal herbs of strengthening body resistanceFlow Cytometrylung cancercell cyclenucleic acidprotein

references

Crissman HA. Simplified method for DNA and protein staining of human hematopoietic cell samples. Cytometry 1982; 2: 59.

Bariogie B, Wolfgang G, Dennis A, et al. Determination of ploidy and proliferative characteristics of human solid tumors pulse cytophotometry. Cancer Res 1978; 38: 3333.

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Related Institution

Department of Respiratory, Zibo Central Hospital

Department of Pharmacy, the Fourth People’s, Hospital of Ji’nan City, Ji’nan

Department of Respiratory, the Second Affiliated Hospital, College of Medicine of Xi’an Jiaotong University

Department of Pharmacy, Harbin Commercial University

Fujian University of Traditional Chinese Medicine

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