Observation on clinical effect of acupuncture on superoxide dismutase, lipid peroxide and nitric oxide in vascular dementia patients

Lai Xinsheng; Mo Feizhi; Jiang Ganghui; Li Jianqiang; Chen Jingliang; Kuang Zaoyuan; Zhang Zheng; Zhang Jiawei; Zheng Zongchang; Peng Zengfu

doi:10.1007/BF02935401

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Observation on clinical effect of acupuncture on superoxide dismutase, lipid peroxide and nitric oxide in vascular dementia patients

Updated：2021-08-27

- Observation on clinical effect of acupuncture on superoxide dismutase, lipid peroxide and nitric oxide in vascular dementia patients
- Chinese Journal of Integrative Medicine Vol. 5, Issue 4, Pages: 269-274(1999)
- Affiliations：
  
  1. Institute of Acupuncture, Guangzhou University of TCM,Guangzhou
  2. Hualan Teacher’s University,Guangzhou
  3. The First Affiliated Hospital of Guangzhou University of TCM,Guangzhou
  4. Guangdong Provincial Hospital of TCM,Guangzhou
- Author bio：
- Funds：
  
  This article is supported financially by the Natural Scientific Fund of Guangdong Province (No. 960548)
- DOI：10.1007/BF02935401
  CLC：
- Published：1999，
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Xinsheng, L., Feizhi, M., Ganghui, J. et al. Observation on clinical effect of acupuncture on superoxide dismutase, lipid peroxide and nitric oxide in vascular dementia patients., CJIM 5, 269–274 (1999). https://doi.org/10.1007/BF02935401

Lai Xinsheng, Mo Feizhi, Jiang Ganghui, et al. Observation on clinical effect of acupuncture on superoxide dismutase, lipid peroxide and nitric oxide in vascular dementia patients. [J]. Chinese Journal of Integrative Medicine 5(4):269-274(1999)
Xinsheng, L., Feizhi, M., Ganghui, J. et al. Observation on clinical effect of acupuncture on superoxide dismutase, lipid peroxide and nitric oxide in vascular dementia patients., CJIM 5, 269–274 (1999). https://doi.org/10.1007/BF02935401 DOI：

Lai Xinsheng, Mo Feizhi, Jiang Ganghui, et al. Observation on clinical effect of acupuncture on superoxide dismutase, lipid peroxide and nitric oxide in vascular dementia patients. [J]. Chinese Journal of Integrative Medicine 5(4):269-274(1999) DOI： 10.1007/BF02935401.

摘要

Objective: To observe the clinical effect of electro acupuncture and acupuncture on superoxide dismutase (SOD)

lipid peroxide (LPO) and nitric oxide (NO) in vascular dementia (VaD) patients.Methods: Forty-six cases of VaD were randomly divided into two groups

the electroacupuncture group (EA group) and the acupuncture group (AP group). Assessment of Hasgawa’s Dementia Scale (HDS)

Functional activities Questionnaire (FAQ) and neurologic deficit scoring (NDS) were determined before and after treatment

and the changes in SOD

LPO and NO levels were observed.Results: After treatment

in the EA group

HDS of patients got elevated

FAQ lowered

SOD increased and LPO and NO decreased. The changes were significant as compared with pretreatment

P < 0. 01. But these parameters underwent no significant changes in the AP group after treatment. The clinical symptoms were improved in both groups

but the reduction in NDS was not significant. The total effective rate of the EA group was higher than that of the AP group.

Abstract

Objective: To observe the clinical effect of electro acupuncture and acupuncture on superoxide dismutase (SOD)

lipid peroxide (LPO) and nitric oxide (NO) in vascular dementia (VaD) patients.Methods: Forty-six cases of VaD were randomly divided into two groups

the electroacupuncture group (EA group) and the acupuncture group (AP group). Assessment of Hasgawa’s Dementia Scale (HDS)

Functional activities Questionnaire (FAQ) and neurologic deficit scoring (NDS) were determined before and after treatment

and the changes in SOD

LPO and NO levels were observed.Results: After treatment

in the EA group

HDS of patients got elevated

FAQ lowered

SOD increased and LPO and NO decreased. The changes were significant as compared with pretreatment

P < 0. 01. But these parameters underwent no significant changes in the AP group after treatment. The clinical symptoms were improved in both groups

but the reduction in NDS was not significant. The total effective rate of the EA group was higher than that of the AP group.

关键词

Vascular Dementiaacupunctureelectroacupuncturesuperoxide dismutaselipid peroxideNitric Oxide

Keywords

Vascular Dementiaacupunctureelectroacupuncturesuperoxide dismutaselipid peroxideNitric Oxide

references

Barnes RF, Raskind MA. DSM-III criteria and the clinical diagnosis of dementia; a nursing home study. J Gerontol 1981; 36(1): 20–27.

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Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University

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