Influence of Buyang Huanwu Decoction on activity of blood platelet activating factor receptor in rabbit) on activity of blood platelet activating factor receptor in rabbit

Zhang Jiping; Li Changling; Guo Xinxin; Wang Yinye

doi:10.1007/BF02935407

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Influence of Buyang Huanwu Decoction on activity of blood platelet activating factor receptor in rabbit) on activity of blood platelet activating factor receptor in rabbit

Updated：2021-08-27

- Influence of Buyang Huanwu Decoction on activity of blood platelet activating factor receptor in rabbit) on activity of blood platelet activating factor receptor in rabbit
- Chinese Journal of Integrative Medicine Vol. 5, Issue 4, Pages: 288-291(1999)
- Affiliations：
  
  Pharmacology Department, College of Pharmacy, Beijing Medical University,Beijing
- Author bio：
- Funds：
  
  This subject supported by Scientific Research Funds of National Administration Bureau of TCM and Pharmacy (93C029)
- DOI：10.1007/BF02935407
  CLC：
- Published：1999，
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Jiping, Z., Changling, L., Xinxin, G. et al. Influence of Buyang Huanwu Decoction on activity of blood platelet activating factor receptor in rabbit) on activity of blood platelet activating factor receptor in rabbit., CJIM 5, 288–291 (1999). https://doi.org/10.1007/BF02935407

Zhang Jiping, Li Changling, Guo Xinxin, et al. Influence of Buyang Huanwu Decoction on activity of blood platelet activating factor receptor in rabbit) on activity of blood platelet activating factor receptor in rabbit. [J]. Chinese Journal of Integrative Medicine 5(4):288-291(1999)
Jiping, Z., Changling, L., Xinxin, G. et al. Influence of Buyang Huanwu Decoction on activity of blood platelet activating factor receptor in rabbit) on activity of blood platelet activating factor receptor in rabbit., CJIM 5, 288–291 (1999). https://doi.org/10.1007/BF02935407 DOI：

Zhang Jiping, Li Changling, Guo Xinxin, et al. Influence of Buyang Huanwu Decoction on activity of blood platelet activating factor receptor in rabbit) on activity of blood platelet activating factor receptor in rabbit. [J]. Chinese Journal of Integrative Medicine 5(4):288-291(1999) DOI： 10.1007/BF02935407.

摘要

Objective: To observe the influence of Buyang Huanwu Decoction (BYHWD) on the activity of blood platelet activating factor receptor (PAFR).Methods: BYHWD was administered to rabbits in vitro or in vivo and its effect on PAFR was observed by radioligand receptor binding method.Results: BYHWD tended to increase the specific binding amount of washed-platelet-PAFR with radioligand in vivo

which was similar to that of Ginkgo leaf extract. And in vitro

it showed an inhibition on the specific binding of washed-platelet-PAFR.Conclusion: BYHWD has certain effect on PAFR amount in vivo and PAFR activity in vitro

Abstract

which was similar to that of Ginkgo leaf extract. And in vitro

it showed an inhibition on the specific binding of washed-platelet-PAFR.Conclusion: BYHWD has certain effect on PAFR amount in vivo and PAFR activity in vitro

关键词

Buyang Huanwu Decoctionplatelet activating factorradioligand receptor binding

Keywords

Buyang Huanwu Decoctionplatelet activating factorradioligand receptor binding

references

Michael N Chang. PAF and PAF antagonists. Drugs Future 1986; 11(10): 869–874.

Joseph R. Welch KMA, D’Andrea G, et al. Platelet activating factor and red blood cells. Thromb Res 1989; 53: 629–633.

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Key Laboratory of Internal Medicine, Hunan University of Traditional Chinese Medicine

Institute of the Integration of Traditional Chinese Medicine and Western Medicine, Xiangya Hospital, Central South University

Department of Neurology, Xiangya Hospital, Central South University

Department of Neurobiology, Xiangya Medical College, Central South University

The 44th PLA Hospital

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