Objective: To find some objective criteria for Syndrome Differentiation of Kidney Deficiency by analysing the relationship between Kidney and hearing as well as serum trace elements.Methods: The hearing and serum trace element of 73 cases of chronic nephropathy were measured.Results: The incidence of hearing damage in high frequency was 68. 5% with a mean hypoacusis of 35.1 ± 6.1 dB

while in the 55 patients of Kidney deficiency type

the incidence of hearing damage in high frequency was 83.6%

which was significantly higher than that in patients without Kidney Deficiency. The serum levels of trace elements (iron and zinc) in patients with Kidney Deficiency were lower than the normal level and that in patients without Kidney Deficiency

and the decrease of serum iron was directly proportional to the degree of hearing damage.Conclusion: There was close relationship between Kidney Deficiency and hearing damage as well as the serum levels of iron and zinc.