Clinical and pathological observation of 106 aplastic anemia patients treated by Spatholobus suberectus composita

Su Eryun; Chen Huishu

doi:10.1007/BF02935466

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Clinical and pathological observation of 106 aplastic anemia patients treated by Spatholobus suberectus composita

Updated：2021-08-27

- Clinical and pathological observation of 106 aplastic anemia patients treated by Spatholobus suberectus composita
- Chinese Journal of Integrative Medicine Vol. 4, Issue 4, Pages: 251-254(1998)
- Affiliations：
  
  1. Affiliated Hospital of Zhejiang University of Technology,Hangzhou
  2. Institute of Hematology, Chinese Academy of Medicinal Science,Tianjin
- Author bio：
- Funds：
- DOI：10.1007/BF02935466
  CLC：
- Published：1998，
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Eryun, S., Huishu, C. Clinical and pathological observation of 106 aplastic anemia patients treated by Spatholobus suberectus composita., CJIM 4, 251–254 (1998). https://doi.org/10.1007/BF02935466

Su Eryun, Chen Huishu. Clinical and pathological observation of 106 aplastic anemia patients treated by Spatholobus suberectus composita. [J]. Chinese Journal of Integrative Medicine 4(4):251-254(1998)
Eryun, S., Huishu, C. Clinical and pathological observation of 106 aplastic anemia patients treated by Spatholobus suberectus composita., CJIM 4, 251–254 (1998). https://doi.org/10.1007/BF02935466 DOI：

Su Eryun, Chen Huishu. Clinical and pathological observation of 106 aplastic anemia patients treated by Spatholobus suberectus composita. [J]. Chinese Journal of Integrative Medicine 4(4):251-254(1998) DOI： 10.1007/BF02935466.

摘要

Objective: To investigate the pharmaceutical effect of Spatholobus suberectus composita (SSC) on bone marrow hematopoiesis and microenvironment of aplastic anemia.Methods: One hundred and six cases of aplastic anemia patients were treated by SSC for 24 months

and the pathological changes of bone marrow of 45 patients were observed before and after treatment

and compared with those of 17 cases of normal volunteers as control.Results: The total effective rate was 77.4%. The volume of nucleated cells changed from 15.7 ± 10.2 vol % to 39.2 ± 13.9 vol%

the percentage of the granulocytes from 31.4 ± 12.4 % to 39.9 ± 10.4%)

the erythroblasts from 19.8 ± 15.9% to 36.7 ± 13.5%

megakaryocytes from 1.4 ± 2.3 cell/section to 24.0 ± 24. 6 cell/section)

and the microvessel number from 40.0 ± 23.4 ves/100mm2 to 201.0 ± 141.0 ves/100mm2)

all the criteria increased significantly (P < 0.01 orP < 0. 05).Conclusion: SSC could not only irritate the hematopoiesis

but also exert reconstructive action to marrow microenvironment.

Abstract

and the pathological changes of bone marrow of 45 patients were observed before and after treatment

and compared with those of 17 cases of normal volunteers as control.Results: The total effective rate was 77.4%. The volume of nucleated cells changed from 15.7 ± 10.2 vol % to 39.2 ± 13.9 vol%

the percentage of the granulocytes from 31.4 ± 12.4 % to 39.9 ± 10.4%)

the erythroblasts from 19.8 ± 15.9% to 36.7 ± 13.5%

megakaryocytes from 1.4 ± 2.3 cell/section to 24.0 ± 24. 6 cell/section)

and the microvessel number from 40.0 ± 23.4 ves/100mm2 to 201.0 ± 141.0 ves/100mm2)

all the criteria increased significantly (P < 0.01 orP < 0. 05).Conclusion: SSC could not only irritate the hematopoiesis

but also exert reconstructive action to marrow microenvironment.

关键词

aplastic anemiaSpatholobus suberectus compositapathology of bone marrow

Keywords

aplastic anemiaSpatholobus suberectus compositapathology of bone marrow

references

Camitta BM, Thomas ED, Nathan DG, et al. A prospective study of androgens and bone marrow transplatation for treatment of severe aplastic anemia. Blood 1979; 53(3):504–514.

Manoharan A. Horsley R, Priney WB. The reticulin content of bone marrowin acute leukemia in adults. Br J Haematol 1979; 43(2):183–190

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Department of Hematology, the First Affi liated Hospital, Zhejiang University of Traditional Chinese Medicine

Department of Hematology, First Clinical Medical College Affiliated to Zhejiang University of Traditional Chinese Medicine

Hematology Disease Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences

Institute of Hematology, The First Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine

Depatment of Hematology, The First Hospital Affiliated to Nanjing Medical University

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