Study of different patterns of immuno-modulatory mechanism by tonifying Kidney and Invigorating Spleen drugs

Shen Ziyin; Cai Dingfang; Zhang Lingjuan; Chen Xiaohong; Zhong Liyong

doi:10.1007/BF02935478

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Study of different patterns of immuno-modulatory mechanism by tonifying Kidney and Invigorating Spleen drugs

Updated：2021-08-27

- Study of different patterns of immuno-modulatory mechanism by tonifying Kidney and Invigorating Spleen drugs
- Chinese Journal of Integrative Medicine Vol. 4, Issue 4, Pages: 278-281(1998)
- Affiliations：
  
  1. Huashan Hospital, Shanghai Medical University,Shanghai
  2. Nanjing Rail-way Medical University,Nanjing
- Author bio：
- Funds：
- DOI：10.1007/BF02935478
  CLC：
- Published：1998，
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Ziyin, S., Dingfang, C., Lingjuan, Z. et al. Study of different patterns of immuno-modulatory mechanism by tonifying Kidney and Invigorating Spleen drugs., CJIM 4, 278–281 (1998). https://doi.org/10.1007/BF02935478

Shen Ziyin, Cai Dingfang, Zhang Lingjuan, et al. Study of different patterns of immuno-modulatory mechanism by tonifying Kidney and Invigorating Spleen drugs. [J]. Chinese Journal of Integrative Medicine 4(4):278-281(1998)
Ziyin, S., Dingfang, C., Lingjuan, Z. et al. Study of different patterns of immuno-modulatory mechanism by tonifying Kidney and Invigorating Spleen drugs., CJIM 4, 278–281 (1998). https://doi.org/10.1007/BF02935478 DOI：

Shen Ziyin, Cai Dingfang, Zhang Lingjuan, et al. Study of different patterns of immuno-modulatory mechanism by tonifying Kidney and Invigorating Spleen drugs. [J]. Chinese Journal of Integrative Medicine 4(4):278-281(1998) DOI： 10.1007/BF02935478.

摘要

Objective: To observe the acting pattern on the immune system by Kidney tonifying (KT) drugs.Methods: Three composite recipes were used on the 7- and 14-day corticosterone rat model to study the effect of recipes on the different patterns of immuno-modulatory and neuro-endocrinological systems.Results: The immune system of Spleen Invigorating (SI) group was well protected in either 7- or 14-day experiments

with the SI recipe showing no effect on the neuroendocrine system. It suggested that SI recipe might have direct action on immune system. On the other hand

KT group with no effect on neuroendocrine-immune (NEI) system in 7-day experiment

but showed a remarkable protective effect of the whole NEI system in 14-day experiment.Conclusion: The results indicated that KT recipe acts on the neuroendocrine system first

and then influence the immune system. It means that the action took place through down pathway of NEI network.

Abstract

with the SI recipe showing no effect on the neuroendocrine system. It suggested that SI recipe might have direct action on immune system. On the other hand

KT group with no effect on neuroendocrine-immune (NEI) system in 7-day experiment

but showed a remarkable protective effect of the whole NEI system in 14-day experiment.Conclusion: The results indicated that KT recipe acts on the neuroendocrine system first

and then influence the immune system. It means that the action took place through down pathway of NEI network.

关键词

Kidney tonifyingSpleen invigoratingcorticosterone ratYouguiyin

Keywords

Kidney tonifyingSpleen invigoratingcorticosterone ratYouguiyin

references

Karalas K. Autocrine or paracrine secretive action of corticotropin-releasing hormone in vivo. Science 1991; 254(10):421–425.

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Zhejiang Traditional Chinese Medicine University

Zhejiang Provincial Institute of Ortopaedics and Traumatology

Ortopaedics and Traumatology Department of Zhejiang Provincial Traditional Chiese Medicine Hospital, the First Affiliated Hospital of Zhejiang Traditional Chinese Medicine University

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