Yang, Sx., Li, Td., Yang, Xs. et al. Protective effect of herba dracocephali on lipoperoxidation damage in patients with coronary heart disease., CJIM 1, 275–277 (1995). https://doi.org/10.1007/BF02940696
Yang Shui-xiang, Li Tian-de, Yang Xing-sheng, et al. Protective effect of herba dracocephali on lipoperoxidation damage in patients with coronary heart disease. [J]. Chinese Journal of Integrative Medicine 1(4):275-277(1995)
Yang, Sx., Li, Td., Yang, Xs. et al. Protective effect of herba dracocephali on lipoperoxidation damage in patients with coronary heart disease., CJIM 1, 275–277 (1995). https://doi.org/10.1007/BF02940696DOI:
Yang Shui-xiang, Li Tian-de, Yang Xing-sheng, et al. Protective effect of herba dracocephali on lipoperoxidation damage in patients with coronary heart disease. [J]. Chinese Journal of Integrative Medicine 1(4):275-277(1995) DOI: 10.1007/BF02940696.
Protective effect of herba dracocephali on lipoperoxidation damage in patients with coronary heart disease
摘要
In order to study the effects of Herba Dracocephali (HD) in treating coronary heart disease (CHD) and antiperoxidative damage
40 patients of CHD were treated with HD and the changes of plasma superoxide dismutase (SOD)
lipid peroxide (LPO)
thromboxane B2 (TXB2) and 6-keto-prostaglandin F1α(6-keto-PGF1α) as well as platelet LPO (PL-LPO)
SOD (PL-SOD) and selenium-glutathion peroxidase (SGP) were measured before and after treatment. Results showed that TXB2
LPO and PL-LPO increased
while SOD
PL-SOD decreased significantly in patients. After treatment by HD
the TXB2
LPO
PL-LPO lowered and 6-keto-PGF1α
SOD
PL-SOD and SGP elevated obviously. Electron microscopy showed that the ultrastructure of platelets improved and the activity of adenylate cyclase increased markedly. The results suggested that HD is a traditional Chinese herbal antioxidant and is hopeful for treating CHD.
Abstract
In order to study the effects of Herba Dracocephali (HD) in treating coronary heart disease (CHD) and antiperoxidative damage
40 patients of CHD were treated with HD and the changes of plasma superoxide dismutase (SOD)
lipid peroxide (LPO)
thromboxane B2 (TXB2) and 6-keto-prostaglandin F1α(6-keto-PGF1α) as well as platelet LPO (PL-LPO)
SOD (PL-SOD) and selenium-glutathion peroxidase (SGP) were measured before and after treatment. Results showed that TXB2
LPO and PL-LPO increased
while SOD
PL-SOD decreased significantly in patients. After treatment by HD
the TXB2
LPO
PL-LPO lowered and 6-keto-PGF1α
SOD
PL-SOD and SGP elevated obviously. Electron microscopy showed that the ultrastructure of platelets improved and the activity of adenylate cyclase increased markedly. The results suggested that HD is a traditional Chinese herbal antioxidant and is hopeful for treating CHD.
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