Lin, P., Yasuhiro, M. & Seiji, M. Effect of magnesium lithosperamate B on D-galactosamine induced liver injury in rats., CJIM 1, 291–293 (1995). https://doi.org/10.1007/BF02940702
Lin Ping, Yasuhiro Mizoguzhi, Seiji Morisawa. Effect of magnesium lithosperamate B on D-galactosamine induced liver injury in rats. [J]. Chinese Journal of Integrative Medicine 1(4):291-293(1995)
Lin, P., Yasuhiro, M. & Seiji, M. Effect of magnesium lithosperamate B on D-galactosamine induced liver injury in rats., CJIM 1, 291–293 (1995). https://doi.org/10.1007/BF02940702DOI:
Lin Ping, Yasuhiro Mizoguzhi, Seiji Morisawa. Effect of magnesium lithosperamate B on D-galactosamine induced liver injury in rats. [J]. Chinese Journal of Integrative Medicine 1(4):291-293(1995) DOI: 10.1007/BF02940702.
Effect of magnesium lithosperamate B on D-galactosamine induced liver injury in rats
摘要
Treated the experimental acute liver injury rat induced by D-galactosamine with magnesium lithosperamate-B could significantly lower the serum activity of alanine transaminase and aspartate aminotransferase
relieve the necrosis of hepatocytes and elevate the levels of products of arachidonic acid (6-ke-to-prostaglandin 1α
prostaglandin D2 and the total prostaglandin) in liver. These results suggested that magnesium lithosperamate B was one of the main components ofSalvia miltiorrzae in treating liver injury
the action on elevating the total prostaglandin in liver might be its mechanism.
Abstract
Treated the experimental acute liver injury rat induced by D-galactosamine with magnesium lithosperamate-B could significantly lower the serum activity of alanine transaminase and aspartate aminotransferase
relieve the necrosis of hepatocytes and elevate the levels of products of arachidonic acid (6-ke-to-prostaglandin 1α
prostaglandin D2 and the total prostaglandin) in liver. These results suggested that magnesium lithosperamate B was one of the main components ofSalvia miltiorrzae in treating liver injury
the action on elevating the total prostaglandin in liver might be its mechanism.
Tanka T, et al. Magnesium and ammonium-potassium lithospermates, the active principles having a ureria-preventive effect from Salvia miltiorrhiza. Chem Pharm Bull 1989;37:340.
Yokozawa T, et al. Effect of magnesium lithospermate B on urinary prostaglandins in rats with renal failure. J Natural Products 1990; 53:662.
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Related Author
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Related Institution
First Hospital, Harbin Medical University
China Academy of Chinese Medical Sciences
Department of Pharmacognosy, Heilongjiang University of Chinese Medicine
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