LPS-induced cellular immunity response and effect of herbal purgation method in intra-abdominal infections

Qin Ming-fang; Wu Xian-zhong

doi:10.1007/BF02942927

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LPS-induced cellular immunity response and effect of herbal purgation method in intra-abdominal infections

Updated：2021-08-27

- LPS-induced cellular immunity response and effect of herbal purgation method in intra-abdominal infections
- Chinese Journal of Integrative Medicine Vol. 1, Issue 3, Pages: 166-170(1995)
- Affiliations：
  
  Tianjin Institute of Acute Abdominal Diseases by Integrated Traditional Chinese and Western Medicine,Tianjin
- Author bio：
- Funds：
- DOI：10.1007/BF02942927
  CLC：
- Published：1995，
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Qin, Mf., Wu, Xz. LPS-induced cellular immunity response and effect of herbal purgation method in intra-abdominal infections., CJIM 1, 166 (1995). https://doi.org/10.1007/BF02942927

Qin Ming-fang, Wu Xian-zhong. LPS-induced cellular immunity response and effect of herbal purgation method in intra-abdominal infections. [J]. Chinese Journal of Integrative Medicine 1(3):166-170(1995)
Qin, Mf., Wu, Xz. LPS-induced cellular immunity response and effect of herbal purgation method in intra-abdominal infections., CJIM 1, 166 (1995). https://doi.org/10.1007/BF02942927 DOI：

Qin Ming-fang, Wu Xian-zhong. LPS-induced cellular immunity response and effect of herbal purgation method in intra-abdominal infections. [J]. Chinese Journal of Integrative Medicine 1(3):166-170(1995) DOI： 10.1007/BF02942927.

摘要

The alterations of cytokines (TNF

PGE2)

plasma lipopolysaccharide andtheir prognostic influences in 58 patients with intra-abdominal infection were observed with enzyme linked immunosorbent assay (ELISA) and radioimmunoassay (RIA). The result revealed earlier improvement of abnormal values of parameters

faster reduction of the level of and detectable rate of serum tumor necrosis factor

higher endotoxin detoxication rate and lower morbidity in the treated group than in the control. The theoretical basis of pharmacological effect and possible mechanism were explored.

Abstract

The alterations of cytokines (TNF

PGE2)

faster reduction of the level of and detectable rate of serum tumor necrosis factor

higher endotoxin detoxication rate and lower morbidity in the treated group than in the control. The theoretical basis of pharmacological effect and possible mechanism were explored.

关键词

intra-abdominal infectionlipopolysaccharidetumor necrosis factorherbal purgation method

Keywords

intra-abdominal infectionlipopolysaccharidetumor necrosis factorherbal purgation method

references

Kacherine F, et al. Bacterial endotoxin and current concepts in the diagnosis and treatment of endotoxemia. J Med Microbiol 1990; 31:73.

Dellinger E, et al. Surgical infection stratification system for intra-abdominal infection. Arch Surg 1985; 120(6):21.

Nystrom PO, et al. Proposed definitions for diagnosis, severity scoring, stratification, and outcome for trials on intra-abdominal infection. World J Surg 1990; 14:148.

Michie HR, et al. Detection of circulating tumor necrosis factor after endotoxin administration. N Eng J Med 1988; 318:1481.

Hesse DG, et al. Cytokine appearance in human endotoxemia and primate bacteremia. Surg Gynecol Obstet 1988; 166:147.

Mathison JC, et al. Participation of tumor necrosis factor in the mediation of gram-negative bacterial lipopolysaccharide induced injury in rabbits. J Clin Invest 1988; 81:1925.

Wang BS, et al. Generation of suppressor cell in mice after surgical trauma. J Clin Invest 1980; 66:200.

Takayama, et al. Elevated tumor necrosis factor production concomitant to elevated prostaglandin E2 production by trauma patients monocytes. Arch Surg 1990; 125:29.

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Related Author

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Related Institution

State Key Laboratory of New-Tech for Chinese Medicine Pharmaceutical Process

Pharmacy College, Jinan University

Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Ministry of Education), Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College

Department of Pharmacology, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing Anzhen Hospital, Capital Medical University

Nanjing University of Traditional Chinese Medicine

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