Protective effects for hepatocytes ofSalviae miltiorrhiza andPaeonia lactiflora in experimental liver damage

Qi Xin-guang; Yutaka Inagaki

doi:10.1007/BF02942942

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Protective effects for hepatocytes ofSalviae miltiorrhiza andPaeonia lactiflora in experimental liver damage

Updated：2021-08-27

- Protective effects for hepatocytes ofSalviae miltiorrhiza andPaeonia lactiflora in experimental liver damage
- Chinese Journal of Integrative Medicine Vol. 1, Issue 3, Pages: 227-230(1995)
- Affiliations：
  
  1. Department of Infectious Diseases, China Medical University,Shenyang
  2. The First Department of Internal Medicine, School of Medicine, Kanazawa University,Japan
- Author bio：
- Funds：
- DOI：10.1007/BF02942942
  CLC：
- Published：1995，
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Qi, Xg., Yutaka, I. Protective effects for hepatocytes ofSalviae miltiorrhiza andPaeonia lactiflora in experimental liver damage., CJIM 1, 227–230 (1995). https://doi.org/10.1007/BF02942942

Qi Xin-guang, Yutaka Inagaki. Protective effects for hepatocytes ofSalviae miltiorrhiza andPaeonia lactiflora in experimental liver damage. [J]. Chinese Journal of Integrative Medicine 1(3):227-230(1995)
Qi, Xg., Yutaka, I. Protective effects for hepatocytes ofSalviae miltiorrhiza andPaeonia lactiflora in experimental liver damage., CJIM 1, 227–230 (1995). https://doi.org/10.1007/BF02942942 DOI：

Qi Xin-guang, Yutaka Inagaki. Protective effects for hepatocytes ofSalviae miltiorrhiza andPaeonia lactiflora in experimental liver damage. [J]. Chinese Journal of Integrative Medicine 1(3):227-230(1995) DOI： 10.1007/BF02942942.

摘要

The protective effects for hepatocytes ofSalviae miltiorrhiza andPaeonia lactiflora in experimental rat models of liver damage were observed. Pathological changes in light and electron micro-scopies and plasma fibronectin level alterations of liver injury in rats

revealed thatSalviae miltiorrhiza could induce the increase of plasma fibronectin level in rats

thus improved phagocytosis of the reticuloendothelial system and opsonin activity

preventing the liver from immunologic damage

protecting hepatocytes and promoting regeneration. Similar but weaker actions were observed inPaeoniae lactiflora.

Abstract

revealed thatSalviae miltiorrhiza could induce the increase of plasma fibronectin level in rats

thus improved phagocytosis of the reticuloendothelial system and opsonin activity

preventing the liver from immunologic damage

protecting hepatocytes and promoting regeneration. Similar but weaker actions were observed inPaeoniae lactiflora.

关键词

Salviae miltiorrhizaPaeonia lactiflorafibronectin

Keywords

Salviae miltiorrhizaPaeonia lactiflorafibronectin

references

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Pater S, et al. Effect of endotoxin on fibronectin and Kupffer cell activity. Hepatology 1985; 5:32.

Bevilacqua MP, et al. Receptors for cold insoluble globulin (plasma fibronectin) on human monocytes. Journal of Experimental Medicine 1981; 153:42.

Kenichi K, et al. Enzyme immunoassay of human plasma fibronectin in malignant collagen and liver disease. Clin Chemi Acta 1983; 131:101.

Saba TM, Jaffe E. Plasma fibronectin (opsonic glycoprotein). Its synthesis by vascular endothelial cells and role in cardiopulmonary integrity after trauma as related to reticuloendothelial function. Am J Med 1980; 68:577.

Michio I, et al. Fibronectin and Kupffer cell function in fulminant hepatic failure. Digestive Diseases and Sciences 1985; 30:1028.

1984; 10:2006.

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