Clinical observation of senile idiopathic nephrotic syndrome treated with integrated traditional chinese and western medicine

Lianbo Wei; Rengao Ye; Xuhong Chen; Zhijun Li; Ruihe Lu; Tu Luan

doi:10.1007/BF02947373

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Clinical observation of senile idiopathic nephrotic syndrome treated with integrated traditional chinese and western medicine

Updated：2021-08-27

- Clinical observation of senile idiopathic nephrotic syndrome treated with integrated traditional chinese and western medicine
- Chinese Journal of Integrative Medicine Vol. 6, Issue 4, Pages: 258-262(2000)
- Affiliations：
  
  1. Department of TCM Internal Medicine, Nanfang Hospital, First Military Medical University,Guangzhou
  2. Institute of Nephropathy, Sun Yat-sen Medical University,China
  3. Training Center of Guangdong Provincial Federation of Deformity,China
- Author bio：
- Funds：
- DOI：10.1007/BF02947373
  CLC：
- Published：2000，
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Wei, L., Ye, R., Chen, X. et al. Clinical observation of senile idiopathic nephrotic syndrome treated with integrated traditional chinese and western medicine., CJIM 6, 258–262 (2000). https://doi.org/10.1007/BF02947373

Lianbo Wei, Rengao Ye, Xuhong Chen, et al. Clinical observation of senile idiopathic nephrotic syndrome treated with integrated traditional chinese and western medicine. [J]. Chinese Journal of Integrative Medicine 6(4):258-262(2000)
Wei, L., Ye, R., Chen, X. et al. Clinical observation of senile idiopathic nephrotic syndrome treated with integrated traditional chinese and western medicine., CJIM 6, 258–262 (2000). https://doi.org/10.1007/BF02947373 DOI：

Lianbo Wei, Rengao Ye, Xuhong Chen, et al. Clinical observation of senile idiopathic nephrotic syndrome treated with integrated traditional chinese and western medicine. [J]. Chinese Journal of Integrative Medicine 6(4):258-262(2000) DOI： 10.1007/BF02947373.

摘要

Objective: To observe the clinical effect of integrated traditional Chinese and western medicine (TCM-WM) in treating senile idiopathic nephrotic syndrome (SINS).Methods: Eighty-two patients of SINS were randomly divided into two groups. The 41 patients in the TCM-WM group were treated with prednisone

Cytoxan (CTX) and Chinese medicinal herbs according to Syndrome-type

and the 41 patients in the control group were treated with western medicine alone. The clinical remission rate and time

recurrence rate in patients as well as adverse reaction rate occurred were observed.Results: The complete remission rate and total effective rate of the TCM-WM group were 58.5% and 85.4 %

which were significantly higher than those of the control group (39.0% and 63.4 %

P < 0.01 ). The adverse reaction rate in the TCM-WM group was 36.6 %

which was significantly lower than that of the control group (80.5%

P<0.01). A follow-up of 35.1 ± 9. 7 months showed that there was no significant difference in the recurrence rate between the two groups (P > 0.05 )

but the average remission period (30.6 ± 3.8 months) of the TCM-WM group was significantly longer than that of the control group (12.7±3.7 months

P<0.01).Conclusion: TCM-WM treatment is obviously superior to that with western medicine alone in increasing clinical remission rate

relieving adverse reaction rate and extending remission period.

Abstract