Clinical and experimental studies on treatment of asthma with Juanxiao tablet

Guangxiang Hong; Yanping Zhang; Jingyao Huang; Wei Wang; Li Ma; Fengda Zhao; Xiguang Fan; Jianjian Chen

doi:10.1007/BF02947378

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Clinical and experimental studies on treatment of asthma with Juanxiao tablet

Updated：2021-08-27

- Clinical and experimental studies on treatment of asthma with Juanxiao tablet
- Chinese Journal of Integrative Medicine Vol. 6, Issue 4, Pages: 271-275(2000)
- Affiliations：
  
  1. Jiangxi College of TCM,Nanchang
  2. Xiyuan Hospital of China Academy of TCM,China
  3. Jiangxi Provincial Hospital of TCM,China
  4. The First Affiliated Hospital of Jiangxi Medical College,China
  5. The Second Affiliated Hospital of Jiangxi Medical College,China
  6. Nanchang Municipal Hospital of Integrated Traditional Chinese and Western Medicine,China
- Author bio：
- Funds：
- DOI：10.1007/BF02947378
  CLC：
- Published：2000，
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Hong, G., Zhang, Y., Huang, J. et al. Clinical and experimental studies on treatment of asthma with Juanxiao tablet., CJIM 6, 271–275 (2000). https://doi.org/10.1007/BF02947378

Guangxiang Hong, Yanping Zhang, Jingyao Huang, et al. Clinical and experimental studies on treatment of asthma with Juanxiao tablet. [J]. Chinese Journal of Integrative Medicine 6(4):271-275(2000)
Hong, G., Zhang, Y., Huang, J. et al. Clinical and experimental studies on treatment of asthma with Juanxiao tablet., CJIM 6, 271–275 (2000). https://doi.org/10.1007/BF02947378 DOI：

Guangxiang Hong, Yanping Zhang, Jingyao Huang, et al. Clinical and experimental studies on treatment of asthma with Juanxiao tablet. [J]. Chinese Journal of Integrative Medicine 6(4):271-275(2000) DOI： 10.1007/BF02947378.

摘要

Objective: To evaluate the therapeutic effect of Juanxiao Tablet (JXT) in treating asthma.Methods: Clinical observation on 447 cases of asthma was done in double- or single-blinded control method

and the therapeutic effect and safety of JXT were analysed. The effect of JXT in anti-asthma

expectorant

antisepsis

hypoxia tolerance was studied

and its acute and chronic toxicity was also examined.Results: The clinical control rate in patients treated with JXT was 38.2 %

the markedly effective rate 31.2% and the total effective rate 93.4 %

whereas in patients treated with Oleum Vitex Negundo

the respective rates were 13.3 %

20.0 % and 68.5%. Results of pulmonary function and IgE measurement were consistent with clinical effect. Experimental study showed that JXT has the actions of anti-asthma

expectorant

antisepsis and hypoxia tolerance enhancement

with its LD50(40.48 ± 5.17) g/kg.Conclusion: JXT is a new Chinese herbal preparation of good effect

with less toxic-side effect for asthma treatment.

Abstract

Objective: To evaluate the therapeutic effect of Juanxiao Tablet (JXT) in treating asthma.Methods: Clinical observation on 447 cases of asthma was done in double- or single-blinded control method

and the therapeutic effect and safety of JXT were analysed. The effect of JXT in anti-asthma

expectorant

antisepsis

hypoxia tolerance was studied

and its acute and chronic toxicity was also examined.Results: The clinical control rate in patients treated with JXT was 38.2 %

the markedly effective rate 31.2% and the total effective rate 93.4 %

whereas in patients treated with Oleum Vitex Negundo

the respective rates were 13.3 %

20.0 % and 68.5%. Results of pulmonary function and IgE measurement were consistent with clinical effect. Experimental study showed that JXT has the actions of anti-asthma

expectorant

antisepsis and hypoxia tolerance enhancement

with its LD50(40.48 ± 5.17) g/kg.Conclusion: JXT is a new Chinese herbal preparation of good effect

with less toxic-side effect for asthma treatment.

关键词

Juanxiao Tabletbronchial asthmaasthma relievingexpectorantbacteriostasis

Keywords

Juanxiao Tabletbronchial asthmaasthma relievingexpectorantbacteriostasis

references

Administration of Pharmacy, Ministry of Health. Guidance on Principles of Clinical Research on New Drugs (Chinese Material Medica), 1988:11–13.

Hong GX. My opinion on treatment of asthma. J of TCM, 1988; (3):7–9.

Huang JY. Pharmacologic study on Dingchuanning (Juanxiao Tablet). China J Chinese Material Medica, 1990;11:45–49.

Xu SY, Bian RL, Chen X. Methodology of Pharmacologic Test. Beijing: People’ s Health Publishing House, 1982:404–408.

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Related Institution

Department of Integrative Chinese and Western Medicine, Huaxi Hospital of Sichuan University

Department of Respiratory Diseases, the First Affiliated Hospital of Nanjing Medical University

Children’s Hospital of Shanghai Medical University

Huakang Pharmaceutical Co. Ltd.

Shanghai University of Traditional Chinese Medicine, Affiliated Longhua Hospital

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