Li, RL., Liu, PL., Wu, XC. et al. Clinical Study on sustained release tablet of tripterygium Wilfordii in treating rheumatoid arthritis., CJIM 2, 111–114 (1996). https://doi.org/10.1007/BF02969658
Rui-Lin Li, Pei-Lin Liu, Xu-Chu Wu, et al. Clinical Study on sustained release tablet of tripterygium Wilfordii in treating rheumatoid arthritis. [J]. Chinese Journal of Integrative Medicine 2(2):111-114(1996)
Li, RL., Liu, PL., Wu, XC. et al. Clinical Study on sustained release tablet of tripterygium Wilfordii in treating rheumatoid arthritis., CJIM 2, 111–114 (1996). https://doi.org/10.1007/BF02969658DOI:
Rui-Lin Li, Pei-Lin Liu, Xu-Chu Wu, et al. Clinical Study on sustained release tablet of tripterygium Wilfordii in treating rheumatoid arthritis. [J]. Chinese Journal of Integrative Medicine 2(2):111-114(1996) DOI: 10.1007/BF02969658.
Clinical Study on sustained release tablet of tripterygium Wilfordii in treating rheumatoid arthritis
摘要
Adopting prospective
multi-center
random
single-blind and equal rank-control methods
226 patients with rheumatoid arthritis (RA) were divided into two groups. The 114 patients of the test group were treated with oral sustained release tablets of Tripterygium Wilfordii (TW-SR)
2 tablets twice a day for 4 weeks
112 patients of the control group received tablets of Tripterygium Wilfordii (TW) orally 2 tablets 3 times per day for 4 weeks. Testing results showed the total effective rates of the two groups were 92.11 % and 90.65 %
respectively (P>0.05). The adverse reaction rate of TW-SR was 20.18%
which was lower than that of TW group of 70.54% (P<0. 01). Results of pre-clinical pharmacologic experimental study demonstrated that TW-SR has obvious anti-inflammatory
analgesic and immunosuppressive actions the same as TW
while the toxicity of TW-SR was less than that of TW significantly.
Abstract
Adopting prospective
multi-center
random
single-blind and equal rank-control methods
226 patients with rheumatoid arthritis (RA) were divided into two groups. The 114 patients of the test group were treated with oral sustained release tablets of Tripterygium Wilfordii (TW-SR)
2 tablets twice a day for 4 weeks
112 patients of the control group received tablets of Tripterygium Wilfordii (TW) orally 2 tablets 3 times per day for 4 weeks. Testing results showed the total effective rates of the two groups were 92.11 % and 90.65 %
respectively (P>0.05). The adverse reaction rate of TW-SR was 20.18%
which was lower than that of TW group of 70.54% (P<0. 01). Results of pre-clinical pharmacologic experimental study demonstrated that TW-SR has obvious anti-inflammatory
analgesic and immunosuppressive actions the same as TW
while the toxicity of TW-SR was less than that of TW significantly.
关键词
rheumatoid arthritisTripterygium Wilfordiisustained release tablet of Tripterygium Wilfordii
Keywords
rheumatoid arthritisTripterygium Wilfordiisustained release tablet of Tripterygium Wilfordii
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Related Author
No data
Related Institution
Research Laboratory of Visceral Manifestation, Huashan Hospital, Shanghai Medical University
Anhui University of Chinese Medicine
Department of Rheumatism Immunity, First Affiliated Hospital, Anhui University of Chinese Medicine
Department of Health Statistics, Third Military Medical University
Department of Rheumatology, Southwest Hospital, Third Military Medical University