Effect of theo-polyphenols on hepatic histology of hyperlipidemia model in quails

Ke Yongsheng; Zhu Xiangming; Zhao Zhendong

doi:10.1007/BF02970588

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Effect of theo-polyphenols on hepatic histology of hyperlipidemia model in quails

Updated：2021-08-27

- Effect of theo-polyphenols on hepatic histology of hyperlipidemia model in quails
- Chinese Journal of Integrative Medicine Vol. 6, Issue 2, Pages: 134-136(2000)
- Affiliations：
  
  Yijishan Hospital, Wannan Medical College,Anhui,Wuhu
- Author bio：
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- DOI：10.1007/BF02970588
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- Published：2000，
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Ke, Y., Zhu, X. & Zhao, Z. Effect of theo-polyphenols on hepatic histology of hyperlipidemia model in quails., CJIM 6, 134–136 (2000). https://doi.org/10.1007/BF02970588

Ke Yongsheng, Zhu Xiangming, Zhao Zhendong. Effect of theo-polyphenols on hepatic histology of hyperlipidemia model in quails. [J]. Chinese Journal of Integrative Medicine 6(2):134-136(2000)
Ke, Y., Zhu, X. & Zhao, Z. Effect of theo-polyphenols on hepatic histology of hyperlipidemia model in quails., CJIM 6, 134–136 (2000). https://doi.org/10.1007/BF02970588 DOI：

Ke Yongsheng, Zhu Xiangming, Zhao Zhendong. Effect of theo-polyphenols on hepatic histology of hyperlipidemia model in quails. [J]. Chinese Journal of Integrative Medicine 6(2):134-136(2000) DOI： 10.1007/BF02970588.

摘要

Objective: To observe the protective effect of theo-polyphenols (TP) on hepatic histology of hyperlipidemia model in quails.Methods: Model of hyperlipidemia in quails was established. The 75 male quails were divided randomly into 5 groups

15 in each group. The non-hyperlipidemia group (normal control group) was fed with ordinary forage. The hyperlipidemia group (hyperlipidemia control group) was fed with high lipid forage. The three TP groups were fed with high lipid forage together with a low (25 mg/kg)

middle (50 mg/ kg) and high (100 mg/kg) dose of TP respectively. The total experimental period was 6 weeks for all the quails.Results: TP could prevent the increase of serum total cholesterol (TC)

triglycerides (TG)

low-density lipoprotein cholesterol (LDL-C) and liver index (LI) caused by high lipid food

thus showing protective dosedependant effect on hepatic histology in hyperlipidemia.Conclusion: TP has the effect of regulating serum lipids in preventing and treating fatty liver.

Abstract

middle (50 mg/ kg) and high (100 mg/kg) dose of TP respectively. The total experimental period was 6 weeks for all the quails.Results: TP could prevent the increase of serum total cholesterol (TC)

triglycerides (TG)

low-density lipoprotein cholesterol (LDL-C) and liver index (LI) caused by high lipid food

thus showing protective dosedependant effect on hepatic histology in hyperlipidemia.Conclusion: TP has the effect of regulating serum lipids in preventing and treating fatty liver.

关键词

theo-polyphenolshyperlipidemiaFatty Liverhistologyquail

Keywords

theo-polyphenolshyperlipidemiaFatty Liverhistologyquail

references

KE Yongsheng, CAO Heng, XU Xiaohua, et al. Effect of theo-polyphenols on oxygen free radicals and hemorheology in patients with primary hypertension. CJIM 1997; 17(4): 221–223.

ZHU Xiangming, ZHAO Zhendong, HUANG Zhili, et al. Experimental study on prevention of hyperlipidemia by theo-polyphenols in quails. CJIM 1996; 16(9): 549–551.

KE Yongsheng, LIU Zhaofang, ZHAO Zhendong. Effect of theo-polyphenols on function of transmembranous signal system of acute ischemic myocardium in rats. CJIM 1999; 5 (3):214–215.

HUANG Mingxin edit. Theory and Practice of Internal Medicine (Vol. 4). Shanghai: Shanghai Publishing House of Sciences and Techniques, 1988:291–292.

HONG Yunxiang, BAO Jun, WANG Zhensheng, et al. Study on effect of tea in activating blood circulation and open vessels. Practical J of Integrated Traditional Chinese and Western Medicine 1989; 2 (1): 47–50.

Ikeda I, Imasato Y, Sasaki E., et al. Tea catechins decrease micellar solubility and intestinal absorption of cholesterol in rats. Biochem Biophys Acta 1992; 1127(2): 141–146.

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