Study on therapeutic effect of compound decoction of comcide in treating withdrawal reaction of heroin dependent rhesuses

Xiaodong Zhang; Xiaohong Guo; Guili Xu; Ling Guo; Zhaojiu Zhang; Yuncheng Hou; Zhengxian Zhang; Lanxi Song; Qingyun Zeng; Jiaxiong Jiang

doi:10.1007/BF02973148

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Study on therapeutic effect of compound decoction of comcide in treating withdrawal reaction of heroin dependent rhesuses

Updated：2021-08-27

- Study on therapeutic effect of compound decoction of comcide in treating withdrawal reaction of heroin dependent rhesuses
- Chinese Journal of Integrative Medicine Vol. 6, Issue 1, Pages: 47-49(2000)
- Affiliations：
  
  1. Institute of Drug Dependent, Kunming Medical College,Kunming
  2. Yunnan Provincial Institute of Materia Medica,china
  3. The First Affiliated Hospital of Kunming Medical College,china
- Author bio：
- Funds：
- DOI：10.1007/BF02973148
  CLC：
- Published：2000，
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Zhang, X., Guo, X., Xu, G. et al. Study on therapeutic effect of compound decoction of comcide in treating withdrawal reaction of heroin dependent rhesuses., CJIM 6, 47–49 (2000). https://doi.org/10.1007/BF02973148

Xiaodong Zhang, Xiaohong Guo, Guili Xu, et al. Study on therapeutic effect of compound decoction of comcide in treating withdrawal reaction of heroin dependent rhesuses. [J]. Chinese Journal of Integrative Medicine 6(1):47-49(2000)
Zhang, X., Guo, X., Xu, G. et al. Study on therapeutic effect of compound decoction of comcide in treating withdrawal reaction of heroin dependent rhesuses., CJIM 6, 47–49 (2000). https://doi.org/10.1007/BF02973148 DOI：

Xiaodong Zhang, Xiaohong Guo, Guili Xu, et al. Study on therapeutic effect of compound decoction of comcide in treating withdrawal reaction of heroin dependent rhesuses. [J]. Chinese Journal of Integrative Medicine 6(1):47-49(2000) DOI： 10.1007/BF02973148.

摘要

Objective: To observe the therapeutic effect of compound decoction of Comcide (CDC)

a traditional Chinese medicine (TCM) in treating the withdrawal reaction (WR) of heroin dependent rhesuses (HDR).Methods: To study therapeutic effects of CDC and methadone in treating WR of HDR models induced by administering of heroin. Through observing

comparing and evaluating the scores of all groups gained during the first 4 days when the WR was most severe.Results: CDC and methadone had the same therapeutic effects on WR of HDR. There were significant differences between the scores of CDC and methadone

and that of natural withdrawal

P < 0. 01; while there were insignificant difference between the scores of CDC and that of methadone

P > 0.05.Conclusion: CDC had the therapeutic effect in treating WR of HDR.

Abstract

Objective: To observe the therapeutic effect of compound decoction of Comcide (CDC)

and that of natural withdrawal

P < 0. 01; while there were insignificant difference between the scores of CDC and that of methadone

P > 0.05.Conclusion: CDC had the therapeutic effect in treating WR of HDR.

关键词

heroin dependent rhesuseswithdrawal therapycompound decoction of Comcide

Keywords

heroin dependent rhesuseswithdrawal therapycompound decoction of Comcide

references

Guo S, Jiang ZN, Wang YD, et al. Clinical controlled study on Fukang tablet and clonidine hydrochloride intreating opioid withdrawal symptoms. Bull Chin Drug Dependence 1995;4(4):210–216.

Guo XH, Zhang XD, Xu GL, et al. The comparison between drug dependence of heroin and morphine. Bull Chin Drug Dependence 1997;6(1):13–17.

Lu SN, Zhang YC, Wang DP, et al. Application of experimental method of detoxication pharmacodynamics of morphine-depedent monkey in evaluating the efficacy of detoxication. Bull Chin Drug Dependence 1995;4(4):205–209.

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