Chen, J., Xu, J., Li, J. et al. Effect of puerarin on fibrinolytic activity and lipid peroxide in patients with coronary heart disease., CJIM 6, 61 (2000). https://doi.org/10.1007/BF02973156
Jiangbin Chen, Jiali Xu, Jianjun Li, et al. Effect of puerarin on fibrinolytic activity and lipid peroxide in patients with coronary heart disease. [J]. Chinese Journal of Integrative Medicine 6(1):61(2000)
Chen, J., Xu, J., Li, J. et al. Effect of puerarin on fibrinolytic activity and lipid peroxide in patients with coronary heart disease., CJIM 6, 61 (2000). https://doi.org/10.1007/BF02973156DOI:
Jiangbin Chen, Jiali Xu, Jianjun Li, et al. Effect of puerarin on fibrinolytic activity and lipid peroxide in patients with coronary heart disease. [J]. Chinese Journal of Integrative Medicine 6(1):61(2000) DOI: 10.1007/BF02973156.
Effect of puerarin on fibrinolytic activity and lipid peroxide in patients with coronary heart disease
摘要
Objective: To observe the effect of puerarin on superoxide dismutase (SOD)
lipid peroxidation (LPO)
tissue plasminogen (TPA) and plasminogen activator inhibitor (PAI-1) of coronary heart disease (CHD) patients.Methods: Forty-eight patients were divided into two groups (treated group and control group). Treated group was given intravenously 600 mg puerarin
once daily for one week
also the same treatment as that of control was given. Nitrite colorimetric method
radioimmunoassay (RIA)
TBA fluorescent development process and fibrinolysin specific colorbase substrate decomposition development process were used to determine SOD activity
SOD
LPO
TPA and PAI-1.Results: After the treatment with puerarin
SOD activity was increased
LPO reduced
while without any changes in the control group. There was insignificant changes of SOD between the treated and the control groups. TPA and PAI-1 were increased significantly in the treated group
but was insignificantly changed in the control group.Conclusion: Puerarin can increase the SOD activity
decrease LPO level and enhance the activity of fibrinolysis.
Abstract
Objective: To observe the effect of puerarin on superoxide dismutase (SOD)
lipid peroxidation (LPO)
tissue plasminogen (TPA) and plasminogen activator inhibitor (PAI-1) of coronary heart disease (CHD) patients.Methods: Forty-eight patients were divided into two groups (treated group and control group). Treated group was given intravenously 600 mg puerarin
once daily for one week
also the same treatment as that of control was given. Nitrite colorimetric method
radioimmunoassay (RIA)
TBA fluorescent development process and fibrinolysin specific colorbase substrate decomposition development process were used to determine SOD activity
SOD
LPO
TPA and PAI-1.Results: After the treatment with puerarin
SOD activity was increased
LPO reduced
while without any changes in the control group. There was insignificant changes of SOD between the treated and the control groups. TPA and PAI-1 were increased significantly in the treated group
but was insignificantly changed in the control group.Conclusion: Puerarin can increase the SOD activity
decrease LPO level and enhance the activity of fibrinolysis.