Differences in effects of Zuojin Pills (左金丸) and its similar formulas on Wei cold model in rats

Yan-ling Zhao; Wen-li Shi; Li-mei Shan; Jia-bo Wang; Hai-ping Zhao; Xiao-he Xiao

doi:10.1007/s11655-009-0293-7

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Differences in effects of Zuojin Pills (左金丸) and its similar formulas on Wei cold model in rats

Updated：2021-08-27

- Differences in effects of Zuojin Pills (左金丸) and its similar formulas on Wei cold model in rats
- Chinese Journal of Integrative Medicine Vol. 15, Issue 4, Pages: 293-298(2009)
- Affiliations：
  
  1. Institute of Traditional Chinese Material Medica, the Hospital of PLA,Beijing,China,302
  2. Department of Integrated Traditional and Western Medicine, the Hospital of PLA,Beijing,China,302
- Author bio：
- Funds：
  
  Supported by National Basic Research Program of China (No. 2007CB512607), National Nature Science Foundation of China (No. 30772740)
- DOI：10.1007/s11655-009-0293-7
  CLC：
- Published：2009，
  
  Published Online：18 August 2009，
Scan for full text
Zhao, Yl., Shi, Wl., Shan, Lm. et al. Differences in effects of Zuojin Pills (左金丸) and its similar formulas on Wei cold model in rats., Chin. J. Integr. Med. 15, 293–298 (2009). https://doi.org/10.1007/s11655-009-0293-7

Yan-ling Zhao, Wen-li Shi, Li-mei Shan, et al. Differences in effects of Zuojin Pills (左金丸) and its similar formulas on Wei cold model in rats. [J]. Chinese Journal of Integrative Medicine 15(4):293-298(2009)
Zhao, Yl., Shi, Wl., Shan, Lm. et al. Differences in effects of Zuojin Pills (左金丸) and its similar formulas on Wei cold model in rats., Chin. J. Integr. Med. 15, 293–298 (2009). https://doi.org/10.1007/s11655-009-0293-7 DOI：

Yan-ling Zhao, Wen-li Shi, Li-mei Shan, et al. Differences in effects of Zuojin Pills (左金丸) and its similar formulas on Wei cold model in rats. [J]. Chinese Journal of Integrative Medicine 15(4):293-298(2009) DOI： 10.1007/s11655-009-0293-7.

摘要

To explore the effects of Zuojin Pills (左金丸) and its similar formulas on the stomach cold syndrome in a Wei cold model in rats. The rat Wei cold model was established by intragastric administration of glacial NaOH

and the gastric mucosa injury indices

together with the levels of motilin and gastrin in the stomach

were determined. The preventive and curative effects of Zuojin Pills and its similar formulas on gastric mucosa injury were investigated. Zuojin Pills and its similar formulas could protect the gastric mucosa in the gastric cold model in rats at different levels. Fanzuojin Pills (反左金丸) had the best effect in inhibiting gastric mucosa injury. The different pharmacological effects of Zuojin Pills and its similar formulas in the rat gastric cold model were partially correlated with the degrees in cold and heat properties of the formulas.

Abstract

and the gastric mucosa injury indices

together with the levels of motilin and gastrin in the stomach

关键词

Zuojin Pillssimilar formularatWei cold syndrome

Keywords

Zuojin Pillssimilar formularatWei cold syndrome

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