Effect of new Pulian Ointment (新普连膏) in treating psoriasis of blood-heat syndrome: A randomized controlled trial

Ning Zhou; Yan-ping Bai; Xiao-hong Man; Yun-bi Zhang; Yu-hong Kong; Hai Ju; Ming Chang

doi:10.1007/s11655-009-0409-0

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Effect of new Pulian Ointment (新普连膏) in treating psoriasis of blood-heat syndrome: A randomized controlled trial

Updated：2021-08-27

- Effect of new Pulian Ointment (新普连膏) in treating psoriasis of blood-heat syndrome: A randomized controlled trial
- Chinese Journal of Integrative Medicine Vol. 15, Issue 6, Pages: 409-414(2009)
- Affiliations：
  
  1. Department of Dermatology, China-Japan Friendship Hospital,Beijing,China
  2. Department of Dermatology, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine,Beijing,China
  3. Department of Dermatology, Dongfang Hospital Affiliated to Beijing University of Chinese Medicine,Beijing,China
- Author bio：
- Funds：
  
  Supported by the Funds of Capital Medicine Development Program (No. 2005-SF-3-086)
- DOI：10.1007/s11655-009-0409-0
  CLC：
- Published：2009，
  
  Published Online：18 January 2010，
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Zhou, N., Bai, Yp., Man, Xh. et al. Effect of new Pulian Ointment (新普连膏) in treating psoriasis of blood-heat syndrome: A randomized controlled trial., Chin. J. Integr. Med. 15, 409–414 (2009). https://doi.org/10.1007/s11655-009-0409-0

Ning Zhou, Yan-ping Bai, Xiao-hong Man, et al. Effect of new Pulian Ointment (新普连膏) in treating psoriasis of blood-heat syndrome: A randomized controlled trial. [J]. Chinese Journal of Integrative Medicine 15(6):409-414(2009)
Zhou, N., Bai, Yp., Man, Xh. et al. Effect of new Pulian Ointment (新普连膏) in treating psoriasis of blood-heat syndrome: A randomized controlled trial., Chin. J. Integr. Med. 15, 409–414 (2009). https://doi.org/10.1007/s11655-009-0409-0 DOI：

Ning Zhou, Yan-ping Bai, Xiao-hong Man, et al. Effect of new Pulian Ointment (新普连膏) in treating psoriasis of blood-heat syndrome: A randomized controlled trial. [J]. Chinese Journal of Integrative Medicine 15(6):409-414(2009) DOI： 10.1007/s11655-009-0409-0.

摘要

To objectively assess the clinical efficacy and safety of a new Pulian Ointment (新普连膏

NPLO) in treating psoriasis of blood-heat syndrome of Chinese medicine. A total of 108 patients with psoriasis of blood-heat syndrome were equally assigned

using a randomizing digital table

to the test group treated externally with NPLO and the control group treated with placebo; the medication was done using a singleblinded method twice a day. Meanwhile

all patients received by oral intake a conventional Chinese decoction for clearing heat and cooling blood; the therapeutic course was 4 weeks for both groups. The therapeutic efficacy

changes in the Psoriasis Area and Severity Index (PASI) score and various aspects of the lesion

including scaly eruption

erythema

infiltration

size

score of itching as well as adverse reactions were observed. The trial was completed in 100 patients

51 in the test group and 49 in the control group. The remarkably effective rate was 45.10% and the total effective rate was 84.31% in the test group

which were significantly higher than those in the control group

12.24% and 51.02%

respectively

showing a significant difference between groups (P<0.01). The test group also showed better effects in the improvement of the PASI score of the lesions and scores on erythema

infiltration

size of lesion as well as itching. No adverse event was found in either group. NPLO is a Chinese remedy for the external treatment of psoriasis of the blood-heat syndrome with a reliable therapeutic efficacy and good safety.

Abstract

To objectively assess the clinical efficacy and safety of a new Pulian Ointment (新普连膏

NPLO) in treating psoriasis of blood-heat syndrome of Chinese medicine. A total of 108 patients with psoriasis of blood-heat syndrome were equally assigned

using a randomizing digital table

to the test group treated externally with NPLO and the control group treated with placebo; the medication was done using a singleblinded method twice a day. Meanwhile

all patients received by oral intake a conventional Chinese decoction for clearing heat and cooling blood; the therapeutic course was 4 weeks for both groups. The therapeutic efficacy

changes in the Psoriasis Area and Severity Index (PASI) score and various aspects of the lesion

including scaly eruption

erythema

infiltration

size

score of itching as well as adverse reactions were observed. The trial was completed in 100 patients

51 in the test group and 49 in the control group. The remarkably effective rate was 45.10% and the total effective rate was 84.31% in the test group

which were significantly higher than those in the control group

12.24% and 51.02%

respectively

showing a significant difference between groups (P<0.01). The test group also showed better effects in the improvement of the PASI score of the lesions and scores on erythema

infiltration

关键词

curative efficacy assessmentnew Pulian Ointmentblood heat syndromepsoriasis

Keywords

curative efficacy assessmentnew Pulian Ointmentblood heat syndromepsoriasis

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