Effect of Yiqi Yangyin Decoction (益气养阴方) on the quality of life of patients with unstable angina pectoris

Qing-yong He; Jie Wang; Yun-ling Zhang; Yan-li Tang; Fu-yong Chu; Xing-jiang Xiong

doi:10.1007/s11655-010-0013-3

Your Location：

Home >

Browse articles >

Effect of Yiqi Yangyin Decoction (益气养阴方) on the quality of life of patients with unstable angina pectoris

Updated：2021-08-27

- Effect of Yiqi Yangyin Decoction (益气养阴方) on the quality of life of patients with unstable angina pectoris
- Chinese Journal of Integrative Medicine Vol. 16, Issue 1, Pages: 13-18(2010)
- Affiliations：
  
  1. Cardiology Department of Guang’anmen Hospital, China Academy of Chinese Medical Sciences,Beijing,China
  2. Department of Traditional Chinese Medical Internal Medicine, Dongfang Hospital, Beijing University of Chinese Medicine,Beijing,China
- Author bio：
- Funds：
  
  Supported by the National Basic Research Program of China (973 Program, No. 2003CB517103), the Traditional Chinese Medicine-treated Characteristic and Dominant Diseases Program of China Academy of Chinese Medical Sciences (No. CACMS05Y0010)
- DOI：10.1007/s11655-010-0013-3
  CLC：
- Published：2010，
  
  Published Online：4 February 2010，
Scan for full text
He, Qy., Wang, J., Zhang, Yl. et al. Effect of Yiqi Yangyin Decoction (益气养阴方) on the quality of life of patients with unstable angina pectoris., Chin. J. Integr. Med. 16, 13–18 (2010). https://doi.org/10.1007/s11655-010-0013-3

Qing-yong He, Jie Wang, Yun-ling Zhang, et al. Effect of Yiqi Yangyin Decoction (益气养阴方) on the quality of life of patients with unstable angina pectoris. [J]. Chinese Journal of Integrative Medicine 16(1):13-18(2010)
He, Qy., Wang, J., Zhang, Yl. et al. Effect of Yiqi Yangyin Decoction (益气养阴方) on the quality of life of patients with unstable angina pectoris., Chin. J. Integr. Med. 16, 13–18 (2010). https://doi.org/10.1007/s11655-010-0013-3 DOI：

Qing-yong He, Jie Wang, Yun-ling Zhang, et al. Effect of Yiqi Yangyin Decoction (益气养阴方) on the quality of life of patients with unstable angina pectoris. [J]. Chinese Journal of Integrative Medicine 16(1):13-18(2010) DOI： 10.1007/s11655-010-0013-3.

摘要

To observe the effect of Yiqi Yangyin Decoction (益气养阴方

YQYYD) on the quality of life (QOL) of patients with unstable angina pectoris (UAP). A total of 108 patients with UAP of qi-yin deficiency syndrome confirmed by coronary angiography were enrolled and assigned to the treated group (treated with YQYYD and conventional therapy of Western medicine) and the control group (treated with conventional therapy of Western medicine)

by the use of the PROC PLAN of the SAS 6.12 software

in a prospective

randomized

controlled design. The clinical total effective rate

symptom score

QOL scale [Seattle Angina Questionnaire (SAQ)] and incidence of important clinical events were defined as the observation indices to evaluate the interventional effect of YQYYD on the QOL of patients with UAP of the qi-yin deficiency syndrome. During the study

three cases dropped out in the treated group

one case dropped out in the control group

and 104 cases

including 51 cases in the treatment group and 53 cases in the control group

finished the trial. After four weeks of treatment

the total clinical effective rates in the treated group and the control group were 80.4% and 75.5% respectively

and there was no obvious difference between them (P>0.05). However

the symptom score of the treated group (9.31±2.02) was significantly lesser than that of the control group (11.62±3.04

P<0.05)

and the total score of the QOL scale of the treated group (68.76±5.74) was significantly higher than that of the control group (61.06±3.31

P<0.01). Among those in the treated group physical limitation

angina stability

angina frequency

and treatment satisfaction were significantly ameliorated when compared with the control group after treatment (P<0.05

P<0.01). The incidence of important clinical events in the treated group (3.9%) was lower than that in the control group (5.7%) during the 8-month follow-up period

but the difference was insignificant (P>0.05). YQYYD could improve the clinical symptoms of patients with UAP of qi-yin deficiency syndrome and greatly improve their QOL.

Abstract

To observe the effect of Yiqi Yangyin Decoction (益气养阴方

by the use of the PROC PLAN of the SAS 6.12 software

in a prospective

randomized

controlled design. The clinical total effective rate

symptom score

three cases dropped out in the treated group

one case dropped out in the control group

and 104 cases

including 51 cases in the treatment group and 53 cases in the control group

finished the trial. After four weeks of treatment

the total clinical effective rates in the treated group and the control group were 80.4% and 75.5% respectively

and there was no obvious difference between them (P>0.05). However

the symptom score of the treated group (9.31±2.02) was significantly lesser than that of the control group (11.62±3.04

P<0.05)

and the total score of the QOL scale of the treated group (68.76±5.74) was significantly higher than that of the control group (61.06±3.31

P<0.01). Among those in the treated group physical limitation

angina stability

angina frequency

and treatment satisfaction were significantly ameliorated when compared with the control group after treatment (P<0.05

P<0.01). The incidence of important clinical events in the treated group (3.9%) was lower than that in the control group (5.7%) during the 8-month follow-up period

but the difference was insignificant (P>0.05). YQYYD could improve the clinical symptoms of patients with UAP of qi-yin deficiency syndrome and greatly improve their QOL.

关键词

Yiqi Yangyin Decoctionunstable angina pectorisSeattle Angina Questionnaireimportant clinical events

Keywords

Yiqi Yangyin Decoctionunstable angina pectorisSeattle Angina Questionnaireimportant clinical events

references

Hu JX. Clinical and experimental study of the effect of Shenshao Tablet on angina pectoris. Chin J Integr Med Cardio-Cerebrovasc Dis (Chin) 2003;1:35–36.

Qiao WJ, Kong JD. Clinical observation of qi-yin supplementing therapy for angina pectoris following coronary heart disease. Shanghai J Tradit Chin Med (Chin) 2002;4(6):10.

Braunwald E, Antman EM, Beasley JW, Califf RM, Cheitlin MD, Hochman JS, et al. ACC/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction-summary article: a report of the American College of Cardiology/American Heart Association task force on practice guidelines (Committee on the Management of Patients with Unstable Angina). J Am Coll Cardiol 2002;40:1366–1374.

Zheng XY, ed. Guiding principles of clinical research on new drugs of traditional Chinese medicine. Beijing: China Medic-Pharmaceutical Sciences and Technology Publishing House; 2002:68–73.

Wang JL, ed. Clinical epidemiology. 2nd ed. Beijing: People’s Medical Publishing House; 2004:173–174.

Wang X, Hu DY, Sha O, Wang CL, Zhao HB, Yang JC. Effect of compound paeonol dripping pill on levels of plasma inflammatory mediators in patients with unstable angina. Chin J Integr Tradit West Med (Chin) 2008;28:395–398.

Tang N, Huang XL, He Y, Lin ZX. Comparison of “Shuxin Decoction” and “Xuefu Zhuyu Decoction” on glycoprotein GP IIb/IIIa and related factors in patients of angina pectoris of coronary. Acta Univ Tradit Med Sinensis Pharmacol Shanghai (Chin) 2007;21(2):25–28.

Wu R, Liu X, Wang J, Zhou XZ. Study on law using Chinese drug of famous old doctor of traditional Chinese medicine to coronary heart disease based on association rules. Chin J Chin Mater Med (Chin) 2007;32:1786–1788.

He QY, Shi Z, Li J, Li HX. Experience of Professor Chen Ding-qi on treating coronary heart disease. Lishizhen Med Mater Med Res (Chin) 2007;18:2612–2613.

Jiang YW. 46 cases of unstable angina pectoris treated by Shenqi Fuzheng Injection. Chin J Integr Tradit West Med (Chin) 2004;24:937–938.

Wu HL, Wang X, Li XM, Luo WJ, Deng TT. Trial study on Deng Tie-tao’s coronary heart disease capsules in improving patients’ quality of life. Chin J Integr Med 2005;11:173–178.

Han P, Li LR. Effect of Chinese medicine on quality of life in patients with perimenopausal syndrome. J Tradit Med (Chin) 2008;49:320–322.

Spertus JA, Winders JA, Dewhurst TA, Deyo RA, Fihn SD. Monitoring the quality of life in patients with coronary artery disease. Am J Cardiac 1994;74:1240–1244.

Garratt AM, Hutchinson A, Russell I. The UK version of the Seattle Angina Questionnaire (SAQ-UK): reliability, validity and responsiveness. J Clin Epidemiol 2001;54:907–915.

Liu TX, Kong SP, Liao ZY, Lu SK. Evaluation study on collective function and quality of life in patients with coronary disease by Seattle Angina Questionnaire. Chin J Behav Med Sci (Chin) 1997;6:127–129.

Jin L, Wang J, Wang T. Evaluation on effects of disassembled formulas of Xuefu Zhuyu Decoction for treatment of angina pectoris using Seattle Angina Questionnaire. Chin J Integr Tradit West Med (Chin) 2007;27:18–20.

FULL TEXT LINK

More>

Views

376

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Effect of Shenshao Tablet (参芍片) on the quality of life for coronary heart disease patients with stable angina pectoris

Effect of Xin’ anning Nasal Drop (心安宁滴鼻剂) in treating coronary heart disease with unstable angina pectoris

Effects of Ginkgo leaf extract on function of dendritic cells and Th1/Th2 cytokines in patients with unstable angina pectoris

Comparative study on the effects of small dose of aspirin combined with Ginkgo-damole injection and the effects of conventional dose of aspirin in treating senile unstable angina pectoris

Effect of Chinese herbs for activating blood circulation, removing stasis and supplementing Qi on the circulating endothelial cells in patients with unstable angina pectoris

Related Author

No data

Related Institution

Guang’anmen Hospital, China Academy of Chinese Medical Sciences

Dongfang Hospital, Beijing University of Chinese Medicine

Department of Cardiopathy, TCM Hospital of Xuzhou City

Nanjing University of TCM

Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
Tel：010-62886827, 62877592 Fax：010-62874291
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰