Treatment of non-alcoholic fatty liver disease by Qianggan Capsule (强肝胶囊)

Li Li; Xiao-jin Zhang; Yu Lan; Le Xu; Xue-zhi Zhang; Hua-hong Wang

doi:10.1007/s11655-010-0023-1

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Treatment of non-alcoholic fatty liver disease by Qianggan Capsule (强肝胶囊)

Updated：2021-08-27

- Treatment of non-alcoholic fatty liver disease by Qianggan Capsule (强肝胶囊)
- Chinese Journal of Integrative Medicine Vol. 16, Issue 1, Pages: 23-27(2010)
- Affiliations：
  
  1. Gastroenterology Department, Beijing Jishuitan Hospital,Beijing,China
  2. Beijing Hospital,Beijing,China
  3. The First Hospital Affiliated to Peking University,Beijing,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-010-0023-1
  CLC：
- Published：2010，
  
  Published Online：4 February 2010，
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Li, L., Zhang, Xj., Lan, Y. et al. Treatment of non-alcoholic fatty liver disease by Qianggan Capsule (强肝胶囊)., Chin. J. Integr. Med. 16, 23–27 (2010). https://doi.org/10.1007/s11655-010-0023-1

Li Li, Xiao-jin Zhang, Yu Lan, et al. Treatment of non-alcoholic fatty liver disease by Qianggan Capsule (强肝胶囊). [J]. Chinese Journal of Integrative Medicine 16(1):23-27(2010)
Li, L., Zhang, Xj., Lan, Y. et al. Treatment of non-alcoholic fatty liver disease by Qianggan Capsule (强肝胶囊)., Chin. J. Integr. Med. 16, 23–27 (2010). https://doi.org/10.1007/s11655-010-0023-1 DOI：

Li Li, Xiao-jin Zhang, Yu Lan, et al. Treatment of non-alcoholic fatty liver disease by Qianggan Capsule (强肝胶囊). [J]. Chinese Journal of Integrative Medicine 16(1):23-27(2010) DOI： 10.1007/s11655-010-0023-1.

摘要

To observe the therapeutic effect and safety of Qianggan Capsule (强肝胶囊

QGC) in treating non-alcoholic fatty liver disease (NAFLD)

using polyene phosphatidylcholine capsule (PPC) as a reference. Eighty-eight patients with NAFLD were randomly assigned to two groups

45 in the treatment group treated with QGC and 43 in the control group treated with PPC. The course of treatment lasted for 6 months. Changes in liver function

blood lipids

and iconographic indexes before and after treatment were observed

and clinical efficacy was evaluated. In the treatment group

alanine aminotransferase (ALT) was lowered significantly from 56.02±32.59 IU/L before treatment to 38.27±22.68 IU/L after treatment

and CT liver/spleen ratio significantly increased from 0.69±0.18 to 0.91±0.25

showing statistical significance (P<0.05); in contrast

the corresponding changes of the two indexes in the control group were 56.56±26.33 IU/L to 49.67±26.22 IU/L

and 0.66±0.20 to 0.75±0.24

respectively

the pre-post treatment difference showing insignificant difference (P>0.05). No severe adverse reactions occurred during the whole treatment course. QGC is an effective and safe remedy for the treatment of NAFLD.

Abstract

To observe the therapeutic effect and safety of Qianggan Capsule (强肝胶囊

QGC) in treating non-alcoholic fatty liver disease (NAFLD)

using polyene phosphatidylcholine capsule (PPC) as a reference. Eighty-eight patients with NAFLD were randomly assigned to two groups

45 in the treatment group treated with QGC and 43 in the control group treated with PPC. The course of treatment lasted for 6 months. Changes in liver function

blood lipids

and iconographic indexes before and after treatment were observed

and clinical efficacy was evaluated. In the treatment group

alanine aminotransferase (ALT) was lowered significantly from 56.02±32.59 IU/L before treatment to 38.27±22.68 IU/L after treatment

and CT liver/spleen ratio significantly increased from 0.69±0.18 to 0.91±0.25

showing statistical significance (P<0.05); in contrast

the corresponding changes of the two indexes in the control group were 56.56±26.33 IU/L to 49.67±26.22 IU/L

and 0.66±0.20 to 0.75±0.24

respectively

关键词

non-alcoholic fatty liver diseaseChinese medicinal therapyQianggan Capsulepolyene phosphatidylcholine capsule

Keywords

non-alcoholic fatty liver diseaseChinese medicinal therapyQianggan Capsulepolyene phosphatidylcholine capsule

references

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Zhang L, Jia JD. Pathogenesis of non-alcoholic fatty liver and pharmacotherapy. Clin Med J (Chin) 2005;3(4):21–23.

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Zeng BH, Huang DZ, Fan LY. Clinical observation of the treatment on fatty liver by Essentiale. Pract Clin J Integr Tradit Chin West Med (Chin) 2006;6(10):25–26.

Ding XC, Ma LN, Zhang X. Influence of Qianggan Capsule on indexes of hepatic fibrosis in patients of chronic liver disease. Chin J Integr Tradit West Med Dig (Chin) 2003;11:351.

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