Clinical observation on the endocrinal and immune functions in subjects with yin-deficiency constitution

Qi Wang; Xiao-juan Ren; Shi-lin Yao; Hong-dong Wu

doi:10.1007/s11655-010-0028-9

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Clinical observation on the endocrinal and immune functions in subjects with yin-deficiency constitution

Updated：2021-08-27

- Clinical observation on the endocrinal and immune functions in subjects with yin-deficiency constitution
- Chinese Journal of Integrative Medicine Vol. 16, Issue 1, Pages: 28-32(2010)
- Affiliations：
  
  1. Medical Research Center of Constitution and Reproductive, Beijing University of Chinese Medicine,Beijing,China
  2. Department of Ache, General Hospital of Armed Police Forces,Beijing,China
  3. Anhui College of Traditional Chinese Medicine,Hefei,China
- Author bio：
- Funds：
  
  Supported by the National Basic Research Program of China (973 Program, No. 2005CB523501)
- DOI：10.1007/s11655-010-0028-9
  CLC：
- Published：2010，
  
  Published Online：4 February 2010，
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Wang, Q., Ren, Xj., Yao, Sl. et al. Clinical observation on the endocrinal and immune functions in subjects with yin-deficiency constitution., Chin. J. Integr. Med. 16, 28–32 (2010). https://doi.org/10.1007/s11655-010-0028-9

Qi Wang, Xiao-juan Ren, Shi-lin Yao, et al. Clinical observation on the endocrinal and immune functions in subjects with yin-deficiency constitution. [J]. Chinese Journal of Integrative Medicine 16(1):28-32(2010)
Wang, Q., Ren, Xj., Yao, Sl. et al. Clinical observation on the endocrinal and immune functions in subjects with yin-deficiency constitution., Chin. J. Integr. Med. 16, 28–32 (2010). https://doi.org/10.1007/s11655-010-0028-9 DOI：

Qi Wang, Xiao-juan Ren, Shi-lin Yao, et al. Clinical observation on the endocrinal and immune functions in subjects with yin-deficiency constitution. [J]. Chinese Journal of Integrative Medicine 16(1):28-32(2010) DOI： 10.1007/s11655-010-0028-9.

摘要

To explore the relationship between yin-deficiency constitution (YDC) and biochemical indexes by way of observing the endocrinal and immune functions in subjects with YDC. On the basis of epidemiological investigation

60 subjects with YDC and 50 with gentle constitution (GC) were selected according to the pertinent criteria. From each subject

8 mL of fasting venous blood was drawn at 8:00–9:00 in the morning

with the serum separated by centrifugation 3 000 r/min for 5 min and preserved at −70°C in a freezer. Serum levels of corticosterone

cortisol

adrenocorticotrophic hormone (ACTH)

cyclic adenosine monophosphate (cAMP)

cyclic guanosine monophosphate (cGMP)

free triiodothyronine (FT3)

free thyroxine (FT4)

throtropic stimulation hormone

interleukin 1β (IL-1β) and interleukin 2 (IL-2) were detected by double-antibody sandwich ELISA; cAMP/cGMP ratio was calculated

and the difference between the two constitutions in terms of these indexes was analyzed. Serum FT3 was 4.16±1.38 pmol/L in subjects with YDC

which was higher than that in subjects with GC (3.71±0.55 pmol/L)

but levels of cortisol (124.58±45.36 ng/mL)

ACTH (58.92±14.55 pg/mL)

cGMP (66.00±18.02 pmol/mL) and FT4 (12.33±3.12 pmol/L) in YDC were lower than those in GC (13.43±2.31 pmol/L)

showing significant difference (P<0.05). YDC is related to some extent with the disturbances in the hypothalamus-pituitary-adrenal axis

hypothalamus-pituitary-thyroid axis

cyclic nucleoside system and immune function.

Abstract

60 subjects with YDC and 50 with gentle constitution (GC) were selected according to the pertinent criteria. From each subject

8 mL of fasting venous blood was drawn at 8:00–9:00 in the morning

with the serum separated by centrifugation 3 000 r/min for 5 min and preserved at −70°C in a freezer. Serum levels of corticosterone

cortisol

adrenocorticotrophic hormone (ACTH)

cyclic adenosine monophosphate (cAMP)

cyclic guanosine monophosphate (cGMP)

free triiodothyronine (FT3)

free thyroxine (FT4)

throtropic stimulation hormone

interleukin 1β (IL-1β) and interleukin 2 (IL-2) were detected by double-antibody sandwich ELISA; cAMP/cGMP ratio was calculated

and the difference between the two constitutions in terms of these indexes was analyzed. Serum FT3 was 4.16±1.38 pmol/L in subjects with YDC

which was higher than that in subjects with GC (3.71±0.55 pmol/L)

but levels of cortisol (124.58±45.36 ng/mL)

ACTH (58.92±14.55 pg/mL)

cGMP (66.00±18.02 pmol/mL) and FT4 (12.33±3.12 pmol/L) in YDC were lower than those in GC (13.43±2.31 pmol/L)

showing significant difference (P<0.05). YDC is related to some extent with the disturbances in the hypothalamus-pituitary-adrenal axis

hypothalamus-pituitary-thyroid axis

cyclic nucleoside system and immune function.

关键词

yin-deficiency constitutionendocrinal functionimmune function

Keywords

yin-deficiency constitutionendocrinal functionimmune function

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