Effect of Gan-Pi regulatory needling in treating chloasma

Hong-fei Shi; Bing Xu; Xi-chao Guo; Xia-wen Qiu; Yu-ping Zhang; Xiang-jie Ding

doi:10.1007/s11655-010-0066-3

Your Location：

Home >

Browse articles >

Effect of Gan-Pi regulatory needling in treating chloasma

Updated：2021-08-27

- Effect of Gan-Pi regulatory needling in treating chloasma
- Chinese Journal of Integrative Medicine Vol. 16, Issue 1, Pages: 66-70(2010)
- Affiliations：
  
  The First Affiliated Hospital of Medical College of Zhejiang University,Hangzhou,China
- Author bio：
- Funds：
  
  Supported by Project of Traditional Chinese Medicine Science and Technology of Zhejiang Province (No. 2006C159)
- DOI：10.1007/s11655-010-0066-3
  CLC：
- Published：2010，
  
  Published Online：4 February 2010，
Scan for full text
Shi, Hf., Xu, B., Guo, Xc. et al. Effect of Gan-Pi regulatory needling in treating chloasma., Chin. J. Integr. Med. 16, 66–70 (2010). https://doi.org/10.1007/s11655-010-0066-3

Hong-fei Shi, Bing Xu, Xi-chao Guo, et al. Effect of Gan-Pi regulatory needling in treating chloasma. [J]. Chinese Journal of Integrative Medicine 16(1):66-70(2010)
Shi, Hf., Xu, B., Guo, Xc. et al. Effect of Gan-Pi regulatory needling in treating chloasma., Chin. J. Integr. Med. 16, 66–70 (2010). https://doi.org/10.1007/s11655-010-0066-3 DOI：

Hong-fei Shi, Bing Xu, Xi-chao Guo, et al. Effect of Gan-Pi regulatory needling in treating chloasma. [J]. Chinese Journal of Integrative Medicine 16(1):66-70(2010) DOI： 10.1007/s11655-010-0066-3.

摘要

To study the effect of Gan (肝)-Pi (脾) regulatory needling (GPRN) in treating chloasma and its influences on female sex hormones

superoxide dismutase (SOD)

lipid peroxide (LPO) and melanocyte-stimulating hormone (MSH). Ninety chloasma patients were equally randomized to three groups

the treatment group treated with GPRN

the control group treated with conventional Western medicine and the blank group untreated. Changes in the scores of skin lesion (area and color) and symptom

as well as blood levels of female sex hormones

MSH

SOD and LPO were observed and compared after 3 months of treatment. In the treatment group

the scores of skin lesion area and color were reduced from 2.76±0.96 and 2.48±0.78 before treatment to 1.42±0.42 and 1.03±0.41 after treatment

respectively

while in the control group they were from 2.78±1.06 and 2.53±0.88 to 1.58±1.23 and 1.28±0.96

respectively

all showing significant changes (P<0.05); the scores were insignificantly changed in the blank group (P>0.05). At the same time

the score of symptoms in the treatment group significantly improved after treatment (P<0.05)

significantly different from that of the other two groups. Comparison of female sex hormones among groups showed no significant differences either before or after treatment. The level of LPO decreased and SOD increased in both the treatment group and the control group significantly (all P<0.05)

but significant lowering of MSH was only seen in the treatment group (P<0.05). GPRN can effectively lessen the size and lighten the color of chloasma

improve the accompanying symptoms in patients and decrease LPO and MSH levels and increase the SOD level

but will not affect the level of the female sex hormones.

Abstract

To study the effect of Gan (肝)-Pi (脾) regulatory needling (GPRN) in treating chloasma and its influences on female sex hormones

superoxide dismutase (SOD)

lipid peroxide (LPO) and melanocyte-stimulating hormone (MSH). Ninety chloasma patients were equally randomized to three groups

the treatment group treated with GPRN

the control group treated with conventional Western medicine and the blank group untreated. Changes in the scores of skin lesion (area and color) and symptom

as well as blood levels of female sex hormones

MSH

SOD and LPO were observed and compared after 3 months of treatment. In the treatment group

the scores of skin lesion area and color were reduced from 2.76±0.96 and 2.48±0.78 before treatment to 1.42±0.42 and 1.03±0.41 after treatment

respectively

while in the control group they were from 2.78±1.06 and 2.53±0.88 to 1.58±1.23 and 1.28±0.96

respectively

all showing significant changes (P<0.05); the scores were insignificantly changed in the blank group (P>0.05). At the same time

the score of symptoms in the treatment group significantly improved after treatment (P<0.05)

but significant lowering of MSH was only seen in the treatment group (P<0.05). GPRN can effectively lessen the size and lighten the color of chloasma

improve the accompanying symptoms in patients and decrease LPO and MSH levels and increase the SOD level

but will not affect the level of the female sex hormones.

关键词

Clinical StudychloasmaGan-Pi regulatory needling

Keywords

Clinical StudychloasmaGan-Pi regulatory needling

references

Chromatopsia Group, Committee of Dermatology and Venereology, Chinese Association of Integrative Medicine. Clinical diagnosis and efficacy standard of chloasma. Chin J Dermatovenereal (Chin) 2004;18:278.

Wang HT, ed. Traditional Chinese cosmetic therapy. Beijing: China Press of Traditional Chinese Medicine; 1997:39–40.

Xia L, Min ZS. Study progression of chloasma treated with traditional Chinese medicine drugs. Modern J Integr Tradit West Med (Chin) 2005;14:1110–1111.

Xu Ck, Chu FJ. The mechanism and syndrome differentiation of chloasma. Liaoning Univ Tradit Chin Med (Chin) 2008;10:30–31.

Shi HF, XU B. Clinical observation on the treatment of chloasma by Chinese herbs combined with acupuncture. Chin J Integr Med 2007;13:219–223.

Li CH, Liu ZR, Yang HL. The overview and treatment of chloasma. Chin J Aesthetic Med (Chin) 2007;16:1147–1150.

Wolf R, Wolf D, Tamir A, Politi Y. Meiasma: a mask of stress. Br J Dermatol 1991;125:192–193.

Xiang YP, Ouyang H. Talk about the relationships of psychic factors, neuropeptide and chloasma. Chin J Inform Tradit Chin Med (Chin) 2003;10:37–38.

Hunt G, Todd C, Cresswel JE, Thody AJ. Alpha-melanocyte stimulating hormone and its analogue Nle4DPhe7 alpha-MSH affect morphology, tyrosinase activity and melanogenesis in cultured human melanocytes. J Cell Sci 1994;107(Pt.1):205–211.

Weng ZS, Cheng JH, Peng JW, Liang RZ. Investigation on some sexual hormone level in female patients with melasma. Southern Chin J Dermato-Venereol (Chin) 2006;13:20–21.

Li J, Wang XY. The measurement of the level of women’s hormone in serum and the curative effect observation of female patients with chloasma. J Clin Dermatol (Chin) 2004;33:738–739.

FULL TEXT LINK

More>

Views

371

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Fuzheng Huayu Capsule (扶正化瘀胶囊) in the treatment of liver fibrosis: Clinical evidence and mechanism of action

Oral herbal medicines for psoriasis: A review of clinical studies

Alleviation of cancerous pain by external compress with Xiaozheng Zhitong Paste (消癥止痛方)

Treatment of inflammatory bowel disease with Chinese drugs administered by both oral intake and retention enema

Effect of Jin-3-needling therapy on plasma corticosteroid, adrenocorticotrophic hormone and platelet 5-HT levels in patients with generalized anxiety disorder

Related Author

No data

Related Institution

Shanghai University of Traditional Chinese Medicine

Guangdong Provincial Academy of Chinese Medical Sciences and Guangdong Provincial Hospital of Chinese Medicine

School of Health Sciences, RMIT University, Bundoora

WHO Collaborating Centre for Traditional Medicine

Traditional & Complementary Medicine Research Program, Health Innovations Research Institute

Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
Tel：010-62886827, 62877592 Fax：010-62874291
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰