Effect of Xuezhikang Capsule (血脂康胶囊) on serum tumor necrosis factor-α and interleukin-6 in patients with nonalcoholic fatty liver disease and hyperlipidemia

Xiao-fen Fan; Yin-quan Deng; Lei Ye; You-di Li; Jiu Chen; Wen-wen Lu; Jian-ping Li

doi:10.1007/s11655-010-0119-7

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Effect of Xuezhikang Capsule (血脂康胶囊) on serum tumor necrosis factor-α and interleukin-6 in patients with nonalcoholic fatty liver disease and hyperlipidemia

Updated：2021-08-27

- Effect of Xuezhikang Capsule (血脂康胶囊) on serum tumor necrosis factor-α and interleukin-6 in patients with nonalcoholic fatty liver disease and hyperlipidemia
- Chinese Journal of Integrative Medicine Vol. 16, Issue 2, Pages: 119-123(2010)
- Affiliations：
  
  1. Department of Traditional Chinese Medicine, The First Affiliated Hospital, College of Medicine, Zhejiang University,Hangzhou,China
  2. Department of Hepatology, Zhejiang Hospital of Traditional Chinese Medicine,Hangzhou,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-010-0119-7
  CLC：
- Published：2010，
  
  Published Online：16 May 2010，
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Fan, Xf., Deng, Yq., Ye, L. et al. Effect of Xuezhikang Capsule (血脂康胶囊) on serum tumor necrosis factor-α and interleukin-6 in patients with nonalcoholic fatty liver disease and hyperlipidemia., Chin. J. Integr. Med. 16, 119–123 (2010). https://doi.org/10.1007/s11655-010-0119-7

Xiao-fen Fan, Yin-quan Deng, Lei Ye, et al. Effect of Xuezhikang Capsule (血脂康胶囊) on serum tumor necrosis factor-α and interleukin-6 in patients with nonalcoholic fatty liver disease and hyperlipidemia. [J]. Chinese Journal of Integrative Medicine 16(2):119-123(2010)
Fan, Xf., Deng, Yq., Ye, L. et al. Effect of Xuezhikang Capsule (血脂康胶囊) on serum tumor necrosis factor-α and interleukin-6 in patients with nonalcoholic fatty liver disease and hyperlipidemia., Chin. J. Integr. Med. 16, 119–123 (2010). https://doi.org/10.1007/s11655-010-0119-7 DOI：

Xiao-fen Fan, Yin-quan Deng, Lei Ye, et al. Effect of Xuezhikang Capsule (血脂康胶囊) on serum tumor necrosis factor-α and interleukin-6 in patients with nonalcoholic fatty liver disease and hyperlipidemia. [J]. Chinese Journal of Integrative Medicine 16(2):119-123(2010) DOI： 10.1007/s11655-010-0119-7.

摘要

To evaluate the effect of Xuezhikang Capsule (血脂康胶囊) on the serum levels of inflammatory factors such as tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in patients with nonalcoholic fatty liver disease (NAFLD) and hyperlipidemia

and to explore whether it has anti-inflammatory effect. A total of 84 patients were randomly assigned to two groups with stratified block randomization

the treatment group (42 cases) and the control group (42 cases). They were treated with Xuezhikang Capsule and polyene phosphatidylcholine capsule for twenty-four weeks

respectively. The changes in serum TNF-α and IL-6 were measured by enzyme linked immunosorbent assay before treatment and at the 12th and 24th week. Compared with those before treatment

the serum levels of TNF-α and IL-6 significantly decreased in both groups after treatment (P<0.01). There was no significant change between the two groups for the treatments at different time points (P>0.05) and between the two groups for treatments at the same time points (P>0.05). Xuezhikang Capsule can inhibit the serum inflammatory factor in patients with NAFLD and hyperlipidemia.

Abstract

and to explore whether it has anti-inflammatory effect. A total of 84 patients were randomly assigned to two groups with stratified block randomization

the treatment group (42 cases) and the control group (42 cases). They were treated with Xuezhikang Capsule and polyene phosphatidylcholine capsule for twenty-four weeks

respectively. The changes in serum TNF-α and IL-6 were measured by enzyme linked immunosorbent assay before treatment and at the 12th and 24th week. Compared with those before treatment

关键词

Xuezhikang capsulenonalcoholic fatty liver diseasehyperlipidemiatumor necrosis factor-αinterleukin-6

Keywords

Xuezhikang capsulenonalcoholic fatty liver diseasehyperlipidemiatumor necrosis factor-αinterleukin-6

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