Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension

Hao Li; Long-tao Liu; Wen-ming Zhao; Jian-gang Liu; Ming-jiang Yao; Yong-xiang Han; Yan-peng Shen; Xing-dong Liu; Li Liu; Xue-mei Wang; Lin-lin Cai; Jie Guan

doi:10.1007/s11655-010-0216-y

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Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension

Updated：2021-08-27

- Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension
- Chinese Journal of Integrative Medicine Vol. 16, Issue 3, Pages: 216-221(2010)
- Affiliations：
  
  1. Xiyuan Hospital, China Academy of Chinese Medical Sciences,Beijing,China
  2. Traditional Chinese Medicine Hospital of Yanqing County,Beijing,China
  3. Community Health Service Centers of Yanqing County,Beijing,China
- Author bio：
- Funds：
  
  Supported by “Eleventh Five-Year” National Science and Technology Support Program of Chinese Medicine Treatment of Common Diseases Project (No. 2007BAI20B07);Science and Technology Research Projects of Capital Medical Development Fund, (No. 03 II 01)
- DOI：10.1007/s11655-010-0216-y
  CLC：
- Published：2010，
  
  Published Online：8 August 2010，
Scan for full text
Li, H., Liu, Lt., Zhao, Wm. et al. Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension., Chin. J. Integr. Med. 16, 216–221 (2010). https://doi.org/10.1007/s11655-010-0216-y

Hao Li, Long-tao Liu, Wen-ming Zhao, et al. Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension. [J]. Chinese Journal of Integrative Medicine 16(3):216-221(2010)
Li, H., Liu, Lt., Zhao, Wm. et al. Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension., Chin. J. Integr. Med. 16, 216–221 (2010). https://doi.org/10.1007/s11655-010-0216-y DOI：

Hao Li, Long-tao Liu, Wen-ming Zhao, et al. Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension. [J]. Chinese Journal of Integrative Medicine 16(3):216-221(2010) DOI： 10.1007/s11655-010-0216-y.

摘要

To observe the effect of Chinese medical regimen and integrative medical regimen on quality of life and early renal impairment in elderly patients with isolated systolic hypertension (EISH). A multi-center

randomized

double-blinded controlled trail was adopted. A total of 270 cases of EISH were randomly divided into 3 groups: Chinese medicine group (CM)

combination group and Western medicine group (WM). The course of treatment was 4 weeks. The clinical blood pressure

integral of quality of life (SF-36 scale)

immunoglubin G (IgG)

microalbumin (mALB)

β2-microglobulin (β2-MG)

transferrin (TRF) and N-acetyl-β′-D-glucosa-minidase (NAG) in urine were determined before and after the treatment. After treatment

systolic blood pressure depressed significantly in each group (P<0.05)

and the combination group was superior to CM or WM group in depressing SBP (P<0.05); in each group

integral of quality of life improved in different degree

and combination group was superior to WM group in all 8 dimensions (P<0.05). The level of mALB and β2-MG in urine decreased in all groups (P<0.05)

and the combination group was superior to CM group or WM group in decreasing mALB (P<0.05). Chinese medical regimen has affirmative effect in treating EISH patients

and could lower the systolic blood pressure

improve quality of life and early renal impairment of the patients

and integrative medical regimen has superiority on account of cooperation

and deserves further study.

Abstract

randomized

double-blinded controlled trail was adopted. A total of 270 cases of EISH were randomly divided into 3 groups: Chinese medicine group (CM)

combination group and Western medicine group (WM). The course of treatment was 4 weeks. The clinical blood pressure

integral of quality of life (SF-36 scale)

immunoglubin G (IgG)

microalbumin (mALB)

β2-microglobulin (β2-MG)

transferrin (TRF) and N-acetyl-β′-D-glucosa-minidase (NAG) in urine were determined before and after the treatment. After treatment

systolic blood pressure depressed significantly in each group (P<0.05)

and the combination group was superior to CM or WM group in depressing SBP (P<0.05); in each group

integral of quality of life improved in different degree

and combination group was superior to WM group in all 8 dimensions (P<0.05). The level of mALB and β2-MG in urine decreased in all groups (P<0.05)

and the combination group was superior to CM group or WM group in decreasing mALB (P<0.05). Chinese medical regimen has affirmative effect in treating EISH patients

and could lower the systolic blood pressure

improve quality of life and early renal impairment of the patients

and integrative medical regimen has superiority on account of cooperation

and deserves further study.

关键词

hypertensionelderlyChinese MedicineIntegrative Medicinequality of lifeearly renal impairment

Keywords

hypertensionelderlyChinese MedicineIntegrative Medicinequality of lifeearly renal impairment

references

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Tang MF. The clinical research of traditional and West integrative medical treatment of the renal damage of hypertension. Chin J Integr Med Cardio-/Cerebrovasc Dis (Chin) 2008;6:1265–1267.

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