Effect of electroacupuncture preconditioning on serum S100β and NSE in patients undergoing craniocerebral tumor resection

Zhi-hong Lu; Xiao-guang Bai; Li-ze Xiong; Yong-hui Wang; Yi Wang; Qiang Wang

doi:10.1007/s11655-010-0229-6

Your Location：

Home >

Browse articles >

Effect of electroacupuncture preconditioning on serum S100β and NSE in patients undergoing craniocerebral tumor resection

Updated：2021-08-27

- Effect of electroacupuncture preconditioning on serum S100β and NSE in patients undergoing craniocerebral tumor resection
- Chinese Journal of Integrative Medicine Vol. 16, Issue 3, Pages: 229-233(2010)
- Affiliations：
  
  Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University,Xi’an,China
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (No.30600840, 30725039, 30772074);Innovative Foundation of Xijing Hospital (No. XJCX05M23)
- DOI：10.1007/s11655-010-0229-6
  CLC：
- Published：2010，
  
  Published Online：8 August 2010，
Scan for full text
Lu, Zh., Bai, Xg., Xiong, Lz. et al. Effect of electroacupuncture preconditioning on serum S100β and NSE in patients undergoing craniocerebral tumor resection., Chin. J. Integr. Med. 16, 229–233 (2010). https://doi.org/10.1007/s11655-010-0229-6

Zhi-hong Lu, Xiao-guang Bai, Li-ze Xiong, et al. Effect of electroacupuncture preconditioning on serum S100β and NSE in patients undergoing craniocerebral tumor resection. [J]. Chinese Journal of Integrative Medicine 16(3):229-233(2010)
Lu, Zh., Bai, Xg., Xiong, Lz. et al. Effect of electroacupuncture preconditioning on serum S100β and NSE in patients undergoing craniocerebral tumor resection., Chin. J. Integr. Med. 16, 229–233 (2010). https://doi.org/10.1007/s11655-010-0229-6 DOI：

Zhi-hong Lu, Xiao-guang Bai, Li-ze Xiong, et al. Effect of electroacupuncture preconditioning on serum S100β and NSE in patients undergoing craniocerebral tumor resection. [J]. Chinese Journal of Integrative Medicine 16(3):229-233(2010) DOI： 10.1007/s11655-010-0229-6.

摘要

To investigate the effect of electroacupuncture preconditioning on the serum level of S100 calcium-binding protein beta (S100β) and neuron-specific enolase (NSE) in patients undergoing craniocerebral tumor operation. A total of 32 patients

who would go through craniocerebral tumor resection under general anesthesia

were randomly assigned to two groups

16 in each group. Patients in the electroacupuncture (EA) group received electroacupuncture on Fengfu acupoint (Du16) and Fengchi acupoint (GB20) for 30 min

2 h before operation. The stimulus is 1–4 mA with a density wave frequency of 2/15 Hz. Patients in the control group received no pretreatment. Anesthesia was maintained with remifentanil at the dose of 4–8 mg/kg per hour

pumped intravenous drip of vecuronium at 1.0–2.0 μg/kg each hour

and discontinuous intravenous dripped with vecuronium bromide at 0.5–1 mg. The serum levels of S100β and NSE were measured with ELISA before operation

before skin incision

after tumor removal

at the end of operation

and at 24 h after operation. The serum level of S100β and NSE did not change before skin incision. The serum level of NSE increased significantly and the level of S100β increased insignificantly after the tumor resection. The serum levels of S100β and NSE in the EA group and the control group were 1.16±0.28 μg/L vs 1.47± 0.33 μg/L

24.7±13.3 μg/L vs 31.4±14.1 μg/L at the end of the operation

respectively. Twenty-four h after operation

the correspondence indices were 1.18±0.31 μg/L vs 1.55±0.26 μg/L

and 25.5±12.4 μg/L vs 32.4± 11.7 μg/L. The two indices at these two time points were significantly increased than those before operation

respectively (P<0.05). At the end of the operation and 24 h post-operation

the serum levels of S100β and NSE in the EA group were significantly lower than those in the control group (P<0.05). Electroacupuncture Fengchi and Fengfu for 30 min before craniocerbral tumor operation could decrease the serum level of S100β and NSE

thus may have potential protective effect on brain damage

which needs to befurther studied.

Abstract

who would go through craniocerebral tumor resection under general anesthesia

were randomly assigned to two groups

16 in each group. Patients in the electroacupuncture (EA) group received electroacupuncture on Fengfu acupoint (Du16) and Fengchi acupoint (GB20) for 30 min

pumped intravenous drip of vecuronium at 1.0–2.0 μg/kg each hour

and discontinuous intravenous dripped with vecuronium bromide at 0.5–1 mg. The serum levels of S100β and NSE were measured with ELISA before operation

before skin incision

after tumor removal

at the end of operation

24.7±13.3 μg/L vs 31.4±14.1 μg/L at the end of the operation

respectively. Twenty-four h after operation

the correspondence indices were 1.18±0.31 μg/L vs 1.55±0.26 μg/L

and 25.5±12.4 μg/L vs 32.4± 11.7 μg/L. The two indices at these two time points were significantly increased than those before operation

respectively (P<0.05). At the end of the operation and 24 h post-operation

thus may have potential protective effect on brain damage

which needs to befurther studied.

关键词

electroacupuncturepreconditioningS100 calcium-binding protein betaneuron-specific enolasecraniotomy

Keywords

electroacupuncturepreconditioningS100 calcium-binding protein betaneuron-specific enolasecraniotomy

references

Xiong LZ, Lu ZH, Hou LC, Zheng HX, Zhu ZH, Wang Q, et al. Pretreatment with repeated electroacupunture attenuates transient focal cerebral ischemic injury in rats. Chin Med J (Chin) 2003; 116:108–111.

Liang JW, Zhang X, Fei Z, Bai H. Postoperative change of NSE in patients with brain tumor. J Fourth Mil Med Univ (Chin) 2002;23:2200–2202.

Gan GS, Wang YL, Wang CY, Chen LM, Chen M, Zhang XJ, et al. Changes of brain injured marker of S100β perioperatively with anesthesia of propofol and the score of mini-mental state examination at six months postoperatively in patients with acute craniocerebral injury. Chin J Clin Rehab (Chin) 2006;10:178–181.

Lu ZH, Xiong LZ, Zhu ZH, wang Q, Zheng Y, Zheng HX, et al. Acupoint specificity of electropuncture’s preconditioning effect on cerebral ischemic injury in rats. Chin Acupunt Moxib (Chin) 2002;22:671–673.

Xiong LZ, Yang J, Wang Q, Lu ZH. Involvement of delta- and mu-opioid receptors in the delayed cerebral ischemic tolerance induced by repeated electroacupuncture preconditioning in rats. Chin Med J 2007;120:394–399.

Wang Q, Xiong LZ, Chen SY, Liu Y, Zhu X. Rapid tolerance to focal cerebral ischemia in rats is induced by preconditioning with electroacupuncture: window of protection and the role of adenosine. Neurosci Letter (Chin) 2005;381:158–162.

Lu ZH, Xiong LZ, Tian L, Liu XL, Liu YH, Chen SY. Pretreatment with repeated electroacupuncture increases HSP70 expression after cerebral ischemic injury in rats. Chin J Anesth (Chin) 2004;24:453–456.

Wang Y, Yang J. Effect of acupuncturing Fengchi and Fengfu on blood supply of the brain in post stroke patients. Clin J Chin Tradit Med (Chin) 2005;17:251–253.

Li XR, Huang LL. Clinical use of Zhang Zhongjing’s acupuncture method. Fujian J Chin Trad Med (Chin) 1998;29:47.

FULL TEXT LINK

More>

Views

349

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Improved mesenchymal stem cell survival in ischemic heart through electroacupuncture

Effect of electroacupuncture on the pathomorphology of the sciatic nerve and the sensitization of P2X3 receptors in the dorsal root ganglion in rats with chronic constrictive injury

Electroacupuncture on PC6 prevents opioid-induced nausea and vomiting after laparoscopic surgery

Effects of electroacupuncture combined psycho-intervention on cognitive function and event-related potentials P300 and mismatch negativity in patients with internet addiction

Related Author

No data

Related Institution

Department of Integrated Chinese and Western Medicine, West China Hospital of Sichuan University

Institute of Cardiovascular Diseases, Pingjin Hospital, Medical College of Armed Police Forces

School of Nursing, Guangzhou University of Chinese Medicine

School of Fundamental Medical Sciences, Guangzhou University of Chinese Medicine

State Key Laboratory of Medicinal Chemical Biology, College of Life Science, Nankai University

Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
Tel：010-62886827, 62877592 Fax：010-62874291
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰